ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1RUW-1.PDB
Scoring matrix: MYO5_1RUW-1_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.95
Foldx random average score for Saccharomyces cerevisiae: 17.326

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1318797
Proteins after disorder filtering: 4147
 Total fragments: 52906
Proteins after pattern filtering: 2086
 Total fragments: 12435
Proteins after MINT filtering: 43
 Total fragments: 759


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.95

-1.85

0.00
Best peptides

RKSRDHMDRF

0.00

-7.38

-5.53
         
Interactors      
P53145

LPPLPGQPPL

15.09

-6.58

-4.73

PLPGQPPLIN

15.16

-7.04

-5.19

NEPLLPPLPG

15.70

-5.87

-4.02
P39113

GPRRPQKNRY

11.32

-7.49

-5.64

RGPRRPQKNR

11.60

-5.45

-3.60

HRGPRRPQKN

12.83

-7.19

-5.34
P40073

QFDGYPQQQP

15.78

-5.21

-3.36
P25604

PKPKSPHLKP

11.46

-6.18

-4.33

LKPPLPPPPP

12.27

-7.54

-5.69

PKSPHLKPPL

12.32

-7.58

-5.73
P25623

SKTKPLPVEP

11.83

-5.96

-4.11

QPPLQPQSKT

15.24

-6.84

-4.99

LPKTVPISIS

15.27

-6.64

-4.79
Q05933

TKFRGPAYPS

9.87

-5.60

-3.75

FRGPAYPSNS

14.39

-5.81

-3.96

TFPVDPNTDR

14.61

-6.62

-4.77
P53094

YPLKLPPLPL

11.60

-9.21

-7.36

VLNVPLPPQT

12.93

-8.85

-7.00

REPNEPPPPC

12.97

-6.49

-4.64
Q12451

LLPWLPPTDT

12.61

-6.48

-4.63

PKHAPPPVPN

13.15

-8.40

-6.55

LPWLPPTDTR

14.45

-7.25

-5.40
P15891

RRATPEKKPK

10.32

-7.26

-5.41

VKTPSPAPAA

13.29

-6.10

-4.25

TPSKSPAPVS

14.24

-5.24

-3.39
P48562

QFPRGPMHPN

10.92

-6.73

-4.88

NPYRPHHNMI

10.95

-7.12

-5.27

PYSKQPQSPL

11.49

-7.09

-5.24
P40341

SRNIPPPPPP

13.16

-8.64

-6.79

RNIPPPPPPP

14.16

-7.41

-5.56

PPPPPPPPPK

14.44

-10.49

-8.64
Q08912

PKGPPPPPPP

13.01

-6.84

-4.99

DHPKGPPPPP

13.09

-7.43

-5.58

TPSWGPSPMG

13.43

-6.54

-4.69
P17555

SKSGPPPRPK

10.92

-7.13

-5.28

PRPKKPSTLK

12.08

-7.27

-5.42

RPKKPSTLKT

13.05

-6.44

-4.59
Q12342

RKAKAPPPPP

7.67

-7.88

-6.03

AKAPPPPPPP

12.76

-8.08

-6.23

APPPPPPPPP

16.03

-7.07

-5.22
P47068

PLPRAPPVPP

11.54

-9.94

-8.09

DKVPPHPVPS

11.95

-7.47

-5.62

MPNTAPPLPR

12.79

-10.49

-8.64
P38822

APEVPPPRRS

13.84

-9.07

-7.22

DRGPAPEVPP

15.45

-4.62

-2.77

PAPEVPPPRR

15.71

-8.84

-6.99
P04050

CLPVPPPPVR

11.55

-7.57

-5.72

PPVRPSISFN

14.60

-5.45

-3.60

LPVPPPPVRP

14.82

-8.74

-6.89
P40450

VPPPPPPPPL

12.69

-9.46

-7.61

DLVTPPAPPL

13.31

-7.92

-6.07

KLPQLPPPPP

13.86

-8.71

-6.86
P40453

RLRKRPPPPP

8.54

-10.17

-8.32

LRKRPPPPPP

8.70

-9.62

-7.77

RKRPPPPPPV

8.89

-7.23

-5.38
Q12168

NRGPPPLPPR

12.57

-9.38

-7.53

VQHPVPKPNI

14.02

-6.81

-4.96

NKVQHPVPKP

14.31

-5.34

-3.49
P41832

VLSSQPPPPP

13.19

-9.01

-7.16

PKGETPPPPP

13.54

-7.76

-5.91

PPPPPPMALF

13.75

-10.45

-8.60
P36006

KKPKNPGGLS

12.13

-7.00

-5.15

GQPKDPKFEA

12.73

-6.30

-4.45

PMGQPKDPKF

13.26

-6.78

-4.93
P38753

TPVMPPQRQS

13.92

-6.80

-4.95

NLPIQHPTNS

15.21

-6.11

-4.26

NNTPVMPPQR

15.57

-6.41

-4.56
P38237

PFVPPPNVPK

14.66

-6.87

-5.02

DLNDPFVPPP

15.24

-7.19

-5.34

NFQIPSKPEN

15.66

-4.77

-2.92
P34245

TPFGPWPGPA

16.23

-6.28

-4.43

AYSTPFGPWP

17.16

-3.74

-1.89

PFGPWPGPAE

17.25

-5.84

-3.99
Q01389

KRSKPLPPQL

9.10

-8.17

-6.32

RRYPQTPSYY

11.32

-6.63

-4.78

PKREAPKPPA

12.51

-7.59

-5.74
Q03306

PRTKPNVPPL

11.63

-5.80

-3.95

KPFRIPSSTK

12.49

-6.59

-4.74

TKPNVPPLQT

12.58

-6.71

-4.86
P34758

HLPPPPPPRA

12.06

-8.74

-6.89

QHLPPPPPPR

13.03

-8.83

-6.98

QLPLEPLKPT

14.26

-7.69

-5.84
P53933

TRRRPPPPPI

7.23

-9.93

-8.08

VRTRRRPPPP

8.25

-8.10

-6.25

RRPPPPPIPS

10.44

-8.14

-6.29
P32381

LLTEPPMNPL

11.03

-10.34

-8.49

ILLTEPPMNP

17.20

-6.45

-4.60
Q00453

SLYAPPYFPH

13.57

-6.07

-4.22

LPHQPPPLPI

14.11

-9.84

-7.99

PHQPPPLPIY

15.06

-6.15

-4.30
P40021

TKNTGPPPPL

10.38

-8.19

-6.34

DFLPSTPSQM

14.11

-8.24

-6.39

VLNSPPLPPP

14.22

-8.84

-6.99
Q12446

RLPAPPPPPR

9.48

-9.85

-8.00

TKHKAPPPPP

9.81

-6.74

-4.89

NRPVPPPPPM

10.61

-8.57

-6.72
Q01560

HQPPEPQPYY

13.92

-4.74

-2.89

YYPPPPPGEH

14.37

-6.91

-5.06

HHQPPEPQPY

14.86

-5.68

-3.83
P00950

RRSFDVPPPP

13.28

-7.00

-5.15

SFDVPPPPID

14.15

-6.19

-4.34

RSFDVPPPPI

15.02

-6.50

-4.65
P53735

PKLVPPPPRT

10.85

-8.19

-6.34

KLVPPPPRTR

12.43

-8.16

-6.31

APKLVPPPPR

13.68

-10.18

-8.33
P33334

MPTRFPPAVF

9.03

-7.52

-5.67

KMPTRFPPAV

12.60

-7.95

-6.10

TLPPPPPPPG

12.93

-9.11

-7.26
P40523

PLAPPPHGPF

12.37

-8.67

-6.82

YMHNSPRNPD

13.42

-8.02

-6.17

VPPLAPPPHG

15.22

-7.36

-5.51
P40563

RRAPPPVPKK

9.91

-7.27

-5.42

PKRRAPPPVP

10.06

-7.15

-5.30

KRRAPPPVPK

11.12

-9.18

-7.33
Q08989

PKGPPPPPPP

13.01

-6.84

-4.99

DHPKGPPPPP

13.09

-7.43

-5.58

PPPPPPPDEK

14.16

-9.59

-7.74
P37370

PKPRPFQNKT

8.94

-5.56

-3.71

PQNRPHMPSV

10.82

-7.06

-5.21

QMPKPRPFQN

11.06

-8.22

-6.37
P39743

AYSNPLTSPV

16.63

-5.36

-3.51
Q03900

TPSGAPKLKN

15.74

-6.27

-4.42

LPNTPSGAPK

16.72

-6.21

-4.36

 


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