ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1R6S-4.PDB
Scoring matrix: MYO5_1R6S-4_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.78
Foldx random average score for Saccharomyces cerevisiae: 18.403

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1394996
Proteins after disorder filtering: 4473
 Total fragments: 93104
Proteins after pattern filtering: 2294
 Total fragments: 21443
Proteins after MINT filtering: 44
 Total fragments: 1404


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.78

-4.26

0.00
Best peptides

WKPRMFRERW

0.00

-1.90

2.36
         
Interactors      
P53145

PPLPGQPPLI

13.01

-8.14

-3.88

NEPLLPPLPG

14.31

-4.46

-0.20

LLPPLPGQPP

14.47

-8.20

-3.94
P39113

GPRRPQKNRY

9.94

-4.50

-0.24

ASHRGPRRPQ

10.38

-5.14

-0.88

HRGPRRPQKN

10.93

-4.61

-0.35
P40073

QFDGYPQQQP

12.99

-3.27

0.99

FDGYPQQQPS

15.53

-3.29

0.97

DGYPQQQPSH

15.96

-1.39

2.87
P25604

LKPPLPPPPP

9.68

-7.80

-3.54

KPPLPPPPPP

10.59

-8.95

-4.69

PKPKSPHLKP

10.77

-5.73

-1.47
P25623

QPPLQPQSKT

12.93

-5.16

-0.90

ASDTPPLPPH

13.58

-4.56

-0.30

EASDTPPLPP

13.59

-5.38

-1.12
Q05933

TKFRGPAYPS

11.84

-3.76

0.50

FRGPAYPSNS

12.53

-3.87

0.39

FPVDPNTDRM

13.07

-5.40

-1.14
P53094

FKSSAFPQSP

8.96

-3.86

0.40

PQTREPNEPP

11.01

-7.10

-2.84

YPLKLPPLPL

11.45

-8.51

-4.25
Q12451

QPHLLPWLPP

11.48

-6.65

-2.39

PKHAPPPVPN

12.03

-6.29

-2.03

APKHAPPPVP

13.19

-5.72

-1.46
P15891

PKPEVPEDEP

11.14

-4.81

-0.55

PPPPPRRATP

12.36

-6.47

-2.21

APPPPPRRAT

12.91

-5.54

-1.28
P48562

QPQRTAPKPP

9.92

-7.80

-3.54

QTMRQAPKRP

9.97

-4.91

-0.65

NPYRPHHNMI

10.57

-7.12

-2.86
P40341

NIPPPPPPPP

9.81

-6.93

-2.67

PPPPPPPPKP

10.93

-9.30

-5.04

PPPPPPPPPK

11.23

-8.49

-4.23
Q08912

PKGPPPPPPP

9.39

-7.94

-3.68

HPKGPPPPPP

9.40

-9.13

-4.87

PPPPPPPDEK

11.29

-8.55

-4.29
P17555

SKSGPPPRPK

10.92

-5.32

-1.06

KSGPPPRPKK

11.30

-4.03

0.23

APPPPPPAPP

11.40

-8.29

-4.03
Q12342

AKAPPPPPPP

9.30

-7.25

-2.99

RKAKAPPPPP

9.48

-6.72

-2.46

APPPPPPPPP

10.92

-8.78

-4.52
P47068

PLPRAPPVPP

9.57

-8.66

-4.40

MPNTAPPLPR

11.84

-8.86

-4.60

PVPPTPPAPP

12.08

-7.16

-2.90
P38822

PAPEVPPPRR

12.44

-7.13

-2.87

DRGPAPEVPP

13.27

-5.42

-1.16

APEVPPPRRS

13.50

-6.44

-2.18
P04050

LPVPPPPVRP

11.77

-7.90

-3.64

CLPVPPPPVR

14.09

-7.88

-3.62

TCLPVPPPPV

14.45

-5.25

-0.99
P40450

QLPPPPPPPP

10.14

-7.71

-3.45

KLPQLPPPPP

10.80

-7.82

-3.56

PPPPPPPPPP

10.86

-9.73

-5.47
P40453

LRKRPPPPPP

8.77

-9.02

-4.76

RKRPPPPPPV

10.62

-6.68

-2.42

RLRKRPPPPP

11.02

-8.69

-4.43
Q12168

NKVQHPVPKP

10.12

-4.63

-0.37

TTNRGPPPLP

11.20

-7.61

-3.35

NRGPPPLPPR

11.83

-5.78

-1.52
P41832

PKGETPPPPP

9.77

-6.90

-2.64

QPPPPPPPPP

9.85

-8.20

-3.94

PPPPPPPPPP

10.86

-9.73

-5.47
P36006

NIPIPPPPPP

9.84

-6.83

-2.57

PPPPPPMGQP

10.81

-8.86

-4.60

PIPPPPPPMG

11.70

-7.84

-3.58
P38753

NTPVMPPQRQ

11.75

-7.13

-2.87

YPSNLPIQHP

12.57

-6.83

-2.57

HANNTPVMPP

13.12

-5.37

-1.11
P38237

DLNDPFVPPP

11.66

-6.21

-1.95

FVPPPNVPKK

12.79

-4.89

-0.63

DPFVPPPNVP

14.13

-5.44

-1.18
P34245

AYSTPFGPWP

15.08

-3.96

0.30

STPFGPWPGP

15.37

-3.14

1.12

GPWPGPAECL

15.90

-5.34

-1.08
Q01389

APKREAPKPP

11.10

-8.52

-4.26

PKREAPKPPA

11.24

-5.08

-0.82

TKSASPPASP

12.43

-5.35

-1.09
Q03306

QPTPSPPLPQ

11.49

-6.64

-2.38

TKPNVPPLQT

11.69

-6.41

-2.15

RNKSIPRTKP

11.99

-5.57

-1.31
P34758

QPQHLPPPPP

10.25

-8.20

-3.94

HLPPPPPPRA

10.33

-6.85

-2.59

PPPPPPRAQQ

10.51

-7.29

-3.03
P53933

TRRRPPPPPI

8.92

-6.87

-2.61

RTRRRPPPPP

9.07

-7.85

-3.59

VRTRRRPPPP

9.96

-6.29

-2.03
P32381

LLTEPPMNPL

13.16

-7.70

-3.44
Q00453

YAPPYFPHPM

11.36

-5.36

-1.10

PIPLPHQPPP

11.66

-7.63

-3.37

APPYFPHPMP

12.04

-7.42

-3.16
P40021

TKNTGPPPPL

11.19

-5.79

-1.53

PPPPLPPPLF

11.38

-9.47

-5.21

NTGPPPPLPP

12.08

-6.34

-2.08
P36150

NPIVVNPSSP

15.29

-4.84

-0.58

PIVVNPSSPS

16.06

-5.67

-1.41
Q12446

HKAPPPPPPT

9.20

-6.13

-1.87

TKHKAPPPPP

10.11

-6.53

-2.27

FPFPVPQQQF

10.57

-5.25

-0.99
Q01560

EPQPYYPPPP

10.49

-7.20

-2.94

YYPPPPPGEH

11.77

-7.15

-2.89

PQPYYPPPPP

12.10

-7.72

-3.46
P00950

RSFDVPPPPI

13.21

-4.62

-0.36

DVPPPPIDAS

14.68

-4.00

0.26

FDVPPPPIDA

15.41

-3.53

0.73
P53735

PKLVPPPPRT

10.79

-5.86

-1.60

APKLVPPPPR

11.76

-8.36

-4.10

LVPPPPRTRS

12.89

-5.09

-0.83
P33334

MPTRFPPAVF

10.07

-8.42

-4.16

FTLPPPPPPP

10.24

-7.77

-3.51

AIPGGPKFEP

11.08

-7.40

-3.14
P40523

YMHNSPRNPD

11.78

-5.73

-1.47

PLAPPPHGPF

12.97

-6.25

-1.99

GVPPLAPPPH

13.30

-5.91

-1.65
P40563

PKRRAPPPVP

8.69

-7.32

-3.06

KRRAPPPVPK

11.06

-6.86

-2.60

RRAPPPVPKK

11.79

-6.43

-2.17
Q08989

PKGPPPPPPP

9.39

-7.94

-3.68

HPKGPPPPPP

9.40

-9.13

-4.87

PPPPPPPDEK

11.29

-8.55

-4.29
P37370

PKPRPFQNKT

7.91

-4.64

-0.38

HKSPSQPPLP

8.75

-6.07

-1.81

MPAPPPPPPP

10.40

-9.15

-4.89
P39743

PNATIPEDNP

16.00

-6.07

-1.81

PAYSNPLTSP

17.46

-4.50

-0.24
Q03900

HLPNTPSGAP

13.32

-5.55

-1.29

NTPSGAPKLK

14.40

-5.61

-1.35

TPSGAPKLKN

14.45

-5.87

-1.61

 


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