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Matrix information:
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ADAN-name: MYO5_1R6S-28.PDB
Scoring matrix: MYO5_1R6S-28_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 33.89
Foldx random average score for Saccharomyces cerevisiae: 33.242 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3199153
Proteins after random average filtering: 7178
Total fragments: 1681712
Proteins after disorder filtering: 4563
Total fragments: 91371
Proteins after pattern filtering: 2186
Total fragments: 12549
Proteins after MINT filtering: 41
Total fragments: 574
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
33.89
|
32.81 |
0.00 |
| Best peptides |
RMPIPRRKGR |
0.00
|
-1.10 |
-33.91 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
EPLLPPLPGQ |
13.59
|
1.89 |
-30.91 |
|
LPPLPGQPPL |
29.18
|
7.02 |
-25.79 |
|
LPGQPPLINI |
29.79
|
9.01 |
-23.80 |
| P39113 |
RGPRRPQKNR |
25.87
|
4.55 |
-28.25 |
|
SHRGPRRPQK |
27.41
|
10.30 |
-22.50 |
|
GPRRPQKNRY |
29.10
|
9.10 |
-23.70 |
| P25604 |
EQNTPPLPPK |
28.59
|
8.18 |
-24.63 |
|
TPPLPPKPKS |
29.34
|
10.59 |
-22.22 |
|
LPPKPKSPHL |
29.59
|
8.79 |
-24.02 |
| P25623 |
SQPPLQPQSK |
27.13
|
8.81 |
-23.99 |
|
TKPLPVEPAS |
28.25
|
7.41 |
-25.40 |
|
LPVEPASPSI |
29.47
|
9.58 |
-23.23 |
| Q05933 |
NFTLPGTPGF |
13.82
|
1.71 |
-31.09 |
|
KFRGPAYPSN |
28.95
|
9.70 |
-23.11 |
|
TFPVDPNTDR |
29.30
|
9.72 |
-23.09 |
| P53094 |
PQSPIRAYGS |
21.71
|
4.80 |
-28.00 |
|
PPCPAMSTGS |
22.74
|
5.73 |
-27.07 |
|
NEPPPPCPAM |
27.12
|
5.68 |
-27.13 |
| Q12451 |
KHAPPPVPNE |
31.25
|
9.41 |
-23.40 |
|
HAPPPVPNET |
31.76
|
10.45 |
-22.36 |
|
LLPWLPPTDT |
32.12
|
10.19 |
-22.62 |
| P15891 |
EVPEDEPEGE |
17.02
|
5.94 |
-26.86 |
|
EAAQPPLPSR |
25.52
|
7.10 |
-25.70 |
|
RRATPEKKPK |
25.92
|
7.16 |
-25.65 |
| P48562 |
KQPQSPLSSQ |
25.65
|
7.77 |
-25.04 |
|
RQAPKRPDAD |
26.02
|
6.88 |
-25.93 |
|
VQPVAPKNDQ |
26.72
|
11.29 |
-21.52 |
| P40341 |
LNDPSNPVSK |
29.07
|
10.48 |
-22.32 |
|
PPPPPPKPPL |
30.91
|
8.67 |
-24.13 |
|
PPPPPPPPPK |
32.64
|
8.33 |
-24.48 |
| Q08912 |
PSWGPSPMGM |
17.47
|
3.14 |
-29.66 |
|
GTHGDHPKGP |
30.20
|
7.75 |
-25.06 |
|
PPPPPDEKDR |
30.82
|
9.17 |
-23.63 |
| P17555 |
KSGPPPRPKK |
25.05
|
7.64 |
-25.16 |
|
PPPRPKKPST |
29.81
|
9.06 |
-23.74 |
|
RPKKPSTLKT |
30.11
|
8.49 |
-24.31 |
| Q12342 |
TPSTPSDGGS |
19.98
|
6.06 |
-26.75 |
|
ETPSTPSDGG |
21.11
|
4.28 |
-28.52 |
|
LETPSTPSDG |
32.33
|
9.81 |
-22.99 |
| P47068 |
RTLPPHVPSL |
27.54
|
8.04 |
-24.77 |
|
PPHVPSLTNR |
28.99
|
6.45 |
-26.36 |
|
SGPVPVPAAT |
29.00
|
8.26 |
-24.55 |
| P38822 |
GDTPTTTPGS |
22.74
|
6.27 |
-26.54 |
|
GPAPEVPPPR |
30.95
|
10.70 |
-22.11 |
|
APEVPPPRRS |
32.62
|
10.10 |
-22.70 |
| P04050 |
YGEAPTSPGF |
16.13
|
3.38 |
-29.43 |
|
EAPTSPGFGV |
18.10
|
4.94 |
-27.86 |
|
PSYSPTSPGY |
20.04
|
3.82 |
-28.98 |
| P40450 |
PPAPPLPNGL |
17.18
|
3.34 |
-29.47 |
|
SPKLFPRLSS |
26.30
|
7.74 |
-25.06 |
|
VSSSPKLFPR |
28.74
|
9.69 |
-23.12 |
| P40453 |
NAWDCPRCGP |
25.37
|
5.55 |
-27.25 |
|
RPPPPPPVSM |
25.95
|
6.11 |
-26.70 |
|
PPDLPIRLRK |
26.58
|
8.67 |
-24.13 |
| Q12168 |
PPPVPNRPGG |
12.70
|
0.48 |
-32.33 |
|
PPVPNRPGGT |
20.89
|
5.44 |
-27.36 |
|
NRGPPPLPPR |
27.41
|
7.40 |
-25.41 |
| P41832 |
PPPPMALFGK |
16.93
|
3.02 |
-29.79 |
|
DGVIPPAPPM |
29.64
|
7.82 |
-24.98 |
|
PPPPPPPMAL |
29.74
|
7.54 |
-25.27 |
| P36006 |
IPPPPPPMGQ |
14.22
|
3.14 |
-29.66 |
|
SNKKPKNPGG |
14.24
|
2.06 |
-30.75 |
|
NKKPKNPGGL |
15.05
|
3.15 |
-29.66 |
| P38753 |
PVMPPQRQSY |
29.85
|
6.58 |
-26.23 |
|
NTPVMPPQRQ |
30.07
|
10.34 |
-22.47 |
|
AHISPPVPGP |
30.24
|
7.35 |
-25.45 |
| P38237 |
NFQIPSKPEN |
28.26
|
9.69 |
-23.12 |
|
FVPPPNVPKK |
29.00
|
9.15 |
-23.66 |
|
FQIPSKPENT |
30.22
|
10.10 |
-22.70 |
| P34245 |
STPFGPWPGP |
26.44
|
7.21 |
-25.59 |
|
FGPWPGPAEC |
30.18
|
10.56 |
-22.24 |
|
GPWPGPAECL |
30.59
|
11.15 |
-21.66 |
| Q01389 |
APTKPNPQGH |
18.34
|
3.05 |
-29.75 |
|
SRTEPSTPSR |
26.25
|
7.02 |
-25.79 |
|
KRSKPLPPQL |
26.46
|
7.41 |
-25.40 |
| Q03306 |
EPSSPPPISR |
27.23
|
8.35 |
-24.45 |
|
GEEKPFRIPS |
28.57
|
9.53 |
-23.27 |
|
KSIPRTKPNV |
29.10
|
9.51 |
-23.30 |
| P34758 |
SQPNKPNYGM |
13.09
|
2.10 |
-30.70 |
|
LPPPPPPRAQ |
27.22
|
7.42 |
-25.38 |
|
QHLPPPPPPR |
28.98
|
6.94 |
-25.86 |
| P53933 |
RVAPPPLPNR |
25.27
|
5.49 |
-27.31 |
|
VSYPGNPTSR |
28.15
|
8.90 |
-23.91 |
|
RPPPPPIPST |
28.84
|
7.12 |
-25.68 |
| P32381 |
LLTEPPMNPL |
28.80
|
7.03 |
-25.77 |
| Q00453 |
YAPPYFPHPM |
29.53
|
8.15 |
-24.66 |
|
SSDTPASPSK |
29.58
|
9.69 |
-23.12 |
|
LPHQPPPLPI |
29.97
|
9.34 |
-23.47 |
| P40021 |
NSPPLPPPAR |
25.28
|
7.25 |
-25.56 |
|
LDFLPSTPSQ |
27.12
|
7.43 |
-25.38 |
|
PLPPPARSQS |
30.30
|
8.50 |
-24.31 |
| Q12446 |
PPPPPASLGQ |
17.95
|
3.38 |
-29.43 |
|
LPQLPNRNNR |
22.79
|
6.47 |
-26.34 |
|
APPPPPRASR |
24.80
|
7.69 |
-25.11 |
| Q01560 |
PYYPPPPPGE |
16.96
|
3.72 |
-29.09 |
|
HQEPPQAPDA |
29.98
|
9.22 |
-23.59 |
|
YYPPPPPGEH |
30.54
|
9.85 |
-22.95 |
| P00950 |
DVPPPPIDAS |
29.91
|
8.06 |
-24.74 |
|
FDVPPPPIDA |
30.60
|
10.21 |
-22.59 |
|
VPPPPIDASS |
32.48
|
10.00 |
-22.81 |
| P53735 |
LVPPPPRTRS |
27.53
|
8.91 |
-23.90 |
|
KLVPPPPRTR |
31.49
|
10.85 |
-21.95 |
|
PKLVPPPPRT |
31.57
|
8.96 |
-23.84 |
| P33334 |
LPPPPPPPGL |
13.81
|
2.80 |
-30.00 |
|
SGLPPPPPGF |
15.53
|
3.10 |
-29.70 |
|
PPPPPPPPGY |
18.46
|
2.93 |
-29.88 |
| P40523 |
PTPVPVPVGV |
16.59
|
3.92 |
-28.88 |
|
NSPRNPDTGT |
17.90
|
4.24 |
-28.56 |
|
YMHNSPRNPD |
27.20
|
9.07 |
-23.73 |
| P40563 |
NSEPPTPAGT |
17.43
|
4.10 |
-28.70 |
|
RRAPPPVPKK |
27.31
|
7.30 |
-25.50 |
|
MEVNSQPQGP |
27.34
|
5.34 |
-27.47 |
| Q08989 |
PPPPPDEKGR |
14.61
|
2.17 |
-30.63 |
|
GTNGDHPKGP |
30.59
|
7.69 |
-25.11 |
|
PPPPPPPDEK |
31.99
|
9.80 |
-23.00 |
| P37370 |
SMSAPPIPGM |
10.78
|
0.92 |
-31.88 |
|
SASAPPIPGA |
16.27
|
3.84 |
-28.97 |
|
PPPPPPALGG |
17.77
|
2.59 |
-30.22 |
| Q03900 |
SHLPNTPSGA |
18.89
|
5.92 |
-26.88 |
|
GSHLPNTPSG |
28.87
|
7.07 |
-25.73 |
|
LPNTPSGAPK |
32.54
|
9.94 |
-22.87 |
|
