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Matrix information:
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ADAN-name: MYO5_1R6S-26.PDB
Scoring matrix: MYO5_1R6S-26_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.58
Foldx random average score for Saccharomyces cerevisiae: 13.282 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3206331
Proteins after random average filtering: 7177
Total fragments: 1309208
Proteins after disorder filtering: 4386
Total fragments: 63074
Proteins after pattern filtering: 2122
Total fragments: 11367
Proteins after MINT filtering: 43
Total fragments: 768
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
16.58
|
-0.70 |
0.00 |
| Best peptides |
DDRHRRPPY |
0.00
|
-4.19 |
-3.49 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
NEPLLPPLP |
10.51
|
-5.53 |
-4.83 |
|
EPLLPPLPG |
12.49
|
-5.15 |
-4.45 |
|
PLPGQPPLI |
12.89
|
-3.89 |
-3.19 |
| P39113 |
GPRRPQKNR |
7.43
|
-3.84 |
-3.14 |
|
SHRGPRRPQ |
7.90
|
-3.05 |
-2.35 |
|
HRGPRRPQK |
9.18
|
-4.22 |
-3.52 |
| P40073 |
GYPQQQPSH |
9.52
|
-5.43 |
-4.73 |
| P25604 |
KSPHLKPPL |
7.88
|
-4.74 |
-4.04 |
|
TPPLPPKPK |
8.30
|
-4.55 |
-3.85 |
|
PKPKSPHLK |
9.36
|
-4.52 |
-3.82 |
| P25623 |
QPPLQPQSK |
10.20
|
-4.30 |
-3.60 |
|
NLPKTVPIS |
10.50
|
-5.19 |
-4.49 |
|
TKPLPVEPA |
11.10
|
-4.63 |
-3.93 |
| Q05933 |
FPVDPNTDR |
11.58
|
-1.60 |
-0.90 |
|
KFRGPAYPS |
12.03
|
-3.13 |
-2.43 |
|
TKFRGPAYP |
12.86
|
-2.44 |
-1.74 |
| P53094 |
FPQSPIRAY |
8.49
|
-4.97 |
-4.27 |
|
DDEDPVSPK |
8.63
|
-3.59 |
-2.89 |
|
NVPLPPQTR |
9.17
|
-5.42 |
-4.72 |
| Q12451 |
APKHAPPPV |
10.08
|
-3.22 |
-2.52 |
|
AAPKHAPPP |
11.04
|
-4.95 |
-4.25 |
|
LLPWLPPTD |
12.30
|
-3.78 |
-3.08 |
| P15891 |
AAPPPPPRR |
9.71
|
-3.34 |
-2.64 |
|
SAAPPPPPR |
9.83
|
-1.97 |
-1.27 |
|
SKKEPVKTP |
10.78
|
-3.05 |
-2.35 |
| P48562 |
IGPAPRPPS |
8.67
|
-4.76 |
-4.06 |
|
THVQPVAPK |
9.03
|
-2.65 |
-1.95 |
|
NGQFPRGPM |
9.20
|
-2.64 |
-1.94 |
| P40341 |
NSRNIPPPP |
9.22
|
-6.16 |
-5.46 |
|
PPPPPPPPK |
9.75
|
-2.78 |
-2.08 |
|
SRNIPPPPP |
10.75
|
-4.19 |
-3.49 |
| Q08912 |
DHPKGPPPP |
9.27
|
-6.27 |
-5.57 |
|
PPPPDEKDR |
11.74
|
-2.38 |
-1.68 |
|
HPKGPPPPP |
11.82
|
-3.84 |
-3.14 |
| P17555 |
SGPPPRPKK |
6.78
|
-1.92 |
-1.22 |
|
PPPRPKKPS |
11.04
|
-5.14 |
-4.44 |
|
RPKKPSTLK |
11.20
|
-1.33 |
-0.63 |
| Q12342 |
KAKAPPPPP |
11.03
|
-4.29 |
-3.59 |
|
RKAKAPPPP |
11.04
|
-4.51 |
-3.81 |
|
KAPPPPPPP |
12.00
|
-2.46 |
-1.76 |
| P47068 |
VPPHPVPSA |
8.98
|
-4.21 |
-3.51 |
|
APPLPRAPP |
9.45
|
-4.40 |
-3.70 |
|
DPSSNPFFR |
9.60
|
-4.41 |
-3.71 |
| P38822 |
PAPEVPPPR |
7.54
|
-5.69 |
-4.99 |
|
APEVPPPRR |
9.43
|
-3.39 |
-2.69 |
|
DTPTTTPGS |
12.89
|
-4.80 |
-4.10 |
| P04050 |
PPPPVRPSI |
10.20
|
-2.82 |
-2.12 |
|
LPVPPPPVR |
10.20
|
-2.26 |
-1.56 |
|
PPVRPSISF |
11.71
|
-3.44 |
-2.74 |
| P40450 |
PPPLPDLFK |
10.12
|
-4.13 |
-3.43 |
|
SSPKLFPRL |
10.37
|
-3.60 |
-2.90 |
|
PKLFPRLSS |
10.48
|
-4.79 |
-4.09 |
| P40453 |
RLRKRPPPP |
8.46
|
-5.18 |
-4.48 |
|
PPDLPIRLR |
8.67
|
-4.59 |
-3.89 |
|
PDLPIRLRK |
9.30
|
-2.27 |
-1.57 |
| Q12168 |
DDPYFPQFR |
8.12
|
-4.98 |
-4.28 |
|
KVQHPVPKP |
9.21
|
-3.18 |
-2.48 |
|
RGPPPLPPR |
9.37
|
-4.43 |
-3.73 |
| P41832 |
PPPPPVPAK |
9.80
|
-3.39 |
-2.69 |
|
DSPAPPPPP |
9.87
|
-5.77 |
-5.07 |
|
DGVIPPAPP |
11.40
|
-4.05 |
-3.35 |
| P36006 |
TANIPIPPP |
9.92
|
-3.87 |
-3.17 |
|
NIPIPPPPP |
9.98
|
-5.83 |
-5.13 |
|
QPKDPKFEA |
10.31
|
-4.76 |
-4.06 |
| P38753 |
NTPVMPPQR |
8.40
|
-5.19 |
-4.49 |
|
NLPIQHPTN |
11.95
|
-5.39 |
-4.69 |
|
SPPVPGPAL |
12.14
|
-1.78 |
-1.08 |
| P38237 |
NDPFVPPPN |
10.06
|
-5.17 |
-4.47 |
|
VPPPNVPKK |
10.22
|
-2.85 |
-2.15 |
|
DPFVPPPNV |
11.78
|
-3.78 |
-3.08 |
| P34245 |
STPFGPWPG |
11.26
|
-4.64 |
-3.94 |
|
TPFGPWPGP |
12.55
|
-3.05 |
-2.35 |
| Q01389 |
PSYPSIFRR |
9.53
|
-2.95 |
-2.25 |
|
RYPQTPSYY |
10.40
|
-4.77 |
-4.07 |
|
SGRRYPQTP |
10.59
|
-2.23 |
-1.53 |
| Q03306 |
SPPLPQMEF |
8.39
|
-4.50 |
-3.80 |
|
EKPFRIPSS |
9.19
|
-5.97 |
-5.27 |
|
SIPRTKPNV |
10.31
|
-4.87 |
-4.17 |
| P34758 |
HLPPPPPPR |
9.32
|
-3.14 |
-2.44 |
|
QPQHLPPPP |
9.87
|
-3.81 |
-3.11 |
|
HSQPNKPNY |
10.16
|
-2.80 |
-2.10 |
| P53933 |
TRRRPPPPP |
7.84
|
-4.49 |
-3.79 |
|
RTRRRPPPP |
8.48
|
-4.84 |
-4.14 |
|
RRRPPPPPI |
10.76
|
-3.48 |
-2.78 |
| P32381 |
LLTEPPMNP |
13.18
|
-3.42 |
-2.72 |
| Q00453 |
YFPHPMPSA |
8.50
|
-4.93 |
-4.23 |
|
PLPHQPPPL |
9.20
|
-4.16 |
-3.46 |
|
HQPPPLPIY |
10.80
|
-4.17 |
-3.47 |
| P40021 |
SPPLPPPAR |
7.14
|
-4.96 |
-4.26 |
|
PPPLPPPLF |
9.19
|
-5.59 |
-4.89 |
|
SESHPPNHP |
11.97
|
-2.00 |
-1.30 |
| Q12446 |
PPPPPRASR |
8.67
|
-2.51 |
-1.81 |
|
PFPFPIPEI |
9.50
|
-6.05 |
-5.35 |
|
PAPPPPPRR |
9.73
|
-3.37 |
-2.67 |
| Q01560 |
QPPEPQPYY |
7.15
|
-6.17 |
-5.47 |
|
PPPSNAPIY |
10.04
|
-4.90 |
-4.20 |
|
PQPYYPPPP |
11.05
|
-5.42 |
-4.72 |
| P00950 |
RSFDVPPPP |
10.34
|
-3.14 |
-2.44 |
|
SFDVPPPPI |
12.12
|
-3.73 |
-3.03 |
| P53735 |
PKLVPPPPR |
9.68
|
-4.55 |
-3.85 |
|
PAPKLVPPP |
10.05
|
-5.76 |
-5.06 |
|
LVPPPPRTR |
10.42
|
-0.95 |
-0.25 |
| P33334 |
GGPKFEPLY |
8.30
|
-5.59 |
-4.89 |
|
SKMPTRFPP |
8.68
|
-2.49 |
-1.79 |
|
PPPPPPPGY |
9.62
|
-4.54 |
-3.84 |
| P40523 |
VPPLAPPPH |
9.29
|
-5.43 |
-4.73 |
|
PPPHGPFST |
10.24
|
-3.28 |
-2.58 |
|
SSVTPQPPS |
10.81
|
-2.72 |
-2.02 |
| P40563 |
RAPPPVPKK |
9.44
|
-2.93 |
-2.23 |
|
KRRAPPPVP |
10.19
|
-4.59 |
-3.89 |
|
EVTPKVPER |
10.21
|
-2.14 |
-1.44 |
| Q08989 |
DHPKGPPPP |
9.27
|
-6.27 |
-5.57 |
|
PPPPDEKGR |
11.51
|
-2.61 |
-1.91 |
|
NGDHPKGPP |
11.66
|
-2.30 |
-1.60 |
| P37370 |
NRPHMPSVR |
7.91
|
-3.40 |
-2.70 |
|
KVPQNRPHM |
8.01
|
-5.07 |
-4.37 |
|
QMPKPRPFQ |
8.66
|
-5.66 |
-4.96 |
| P39743 |
SNPLTSPVA |
12.03
|
-3.73 |
-3.03 |
| Q03900 |
TPSGAPKLK |
12.39
|
-1.66 |
-0.96 |
|
NTPSGAPKL |
12.81
|
-3.86 |
-3.16 |
|
