ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1R6S-1.PDB
Scoring matrix: MYO5_1R6S-1_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.14
Foldx random average score for Saccharomyces cerevisiae: 14.905

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199153
Proteins after random average filtering: 7178
 Total fragments: 1361267
Proteins after disorder filtering: 4123
 Total fragments: 58060
Proteins after pattern filtering: 2159
 Total fragments: 15892
Proteins after MINT filtering: 44
 Total fragments: 1096


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.14

-4.09

0.00
Best peptides

RRSKRIMDRY

0.00

-4.53

-0.44
         
Interactors      
P53145

PLLPPLPGQP

10.33

-9.25

-5.16

LLPPLPGQPP

11.69

-8.32

-4.23

LPPLPGQPPL

12.96

-6.47

-2.38
P39113

HRGPRRPQKN

8.64

-7.39

-3.30

GPRRPQKNRY

9.47

-7.66

-3.57

RGPRRPQKNR

9.55

-4.71

-0.62
P40073

QFDGYPQQQP

13.33

-5.73

-1.64

GYPQQQPSHT

13.41

-3.18

0.91
P25604

PKPKSPHLKP

8.98

-6.49

-2.40

KPPLPPPPPP

8.98

-10.58

-6.49

LKPPLPPPPP

9.05

-9.94

-5.85
P25623

SKTKPLPVEP

7.40

-8.31

-4.22

ISISQPPLQP

11.83

-7.06

-2.97

NLPKTVPISI

12.15

-4.88

-0.79
Q05933

FRGPAYPSNS

11.54

-5.69

-1.60

TKFRGPAYPS

12.32

-5.72

-1.63

FPVDPNTDRM

13.13

-6.13

-2.04
P53094

YPLKLPPLPL

8.38

-9.19

-5.10

CYPLKLPPLP

9.48

-6.84

-2.75

VLNVPLPPQT

9.64

-8.82

-4.73
Q12451

APKHAPPPVP

11.47

-8.35

-4.26

QPHLLPWLPP

12.20

-8.84

-4.75

PKHAPPPVPN

12.40

-7.47

-3.38
P15891

RRATPEKKPK

8.28

-7.12

-3.03

RSSAAPPPPP

9.59

-7.82

-3.73

SRSSAAPPPP

9.95

-6.21

-2.12
P48562

QPQRTAPKPP

8.86

-8.75

-4.66

PYSKQPQSPL

9.06

-6.25

-2.16

RQAPKRPDAD

9.60

-5.52

-1.43
P40341

SRNIPPPPPP

8.02

-8.25

-4.16

NNSRNIPPPP

8.98

-7.59

-3.50

RNIPPPPPPP

9.06

-7.33

-3.24
Q08912

DHPKGPPPPP

7.22

-9.32

-5.23

HPKGPPPPPP

10.10

-8.75

-4.66

PKGPPPPPPP

10.19

-7.43

-3.34
P17555

SKSGPPPRPK

9.79

-7.68

-3.59

RPKKPSTLKT

10.17

-5.83

-1.74

PRPKKPSTLK

10.69

-8.44

-4.35
Q12342

RKAKAPPPPP

4.66

-7.88

-3.79

AKAPPPPPPP

9.77

-9.54

-5.45

APPPPPPPPP

10.38

-9.21

-5.12
P47068

PLPRAPPVPP

8.30

-10.83

-6.74

MPNTAPPLPR

10.85

-10.01

-5.92

RAPPVPPATF

11.23

-5.76

-1.67
P38822

APEVPPPRRS

11.30

-8.69

-4.60

DRGPAPEVPP

12.30

-8.21

-4.12

PAPEVPPPRR

13.07

-8.57

-4.48
P04050

LPVPPPPVRP

9.50

-9.35

-5.26

CLPVPPPPVR

10.13

-9.61

-5.52

AYGEAPTSPG

13.10

-5.20

-1.11
P40450

KLPQLPPPPP

8.23

-9.15

-5.06

LPQLPPPPPP

9.16

-11.78

-7.69

QLPPPPPPPP

9.32

-9.14

-5.05
P40453

RLRKRPPPPP

3.29

-9.17

-5.08

IRLRKRPPPP

4.32

-8.16

-4.07

LRKRPPPPPP

4.94

-9.38

-5.29
Q12168

NKVQHPVPKP

11.00

-6.75

-2.66

NRGPPPLPPR

11.02

-8.79

-4.70

RGPPPLPPRA

11.35

-5.86

-1.77
P41832

VLSSQPPPPP

8.68

-9.57

-5.48

SQPPPPPPPP

9.85

-9.29

-5.20

QPPPPPPPPP

9.98

-9.96

-5.87
P36006

IPIPPPPPPM

9.69

-8.01

-3.92

GQPKDPKFEA

10.35

-8.00

-3.91

KSNKKPKNPG

10.98

-6.50

-2.41
P38753

PYPSNLPIQH

9.86

-6.74

-2.65

THANNTPVMP

11.73

-6.80

-2.71

TPVMPPQRQS

12.48

-6.49

-2.40
P38237

DLNDPFVPPP

11.19

-7.63

-3.54

DPFVPPPNVP

11.30

-8.96

-4.87

VPPPNVPKKD

12.63

-8.31

-4.22
P34245

AYSTPFGPWP

12.19

-5.89

-1.80

TPFGPWPGPA

13.95

-6.61

-2.52
Q01389

KRSKPLPPQL

5.01

-8.12

-4.03

RRYPQTPSYY

7.48

-4.18

-0.09

APKREAPKPP

9.22

-7.97

-3.88
Q03306

GYRQPTPSPP

9.76

-6.88

-2.79

RNKSIPRTKP

9.81

-6.57

-2.48

RQPTPSPPLP

10.02

-5.94

-1.85
P34758

QQPQHLPPPP

8.60

-6.54

-2.45

QHLPPPPPPR

9.52

-7.88

-3.79

QPQHLPPPPP

9.91

-7.95

-3.86
P53933

VRTRRRPPPP

3.39

-8.04

-3.95

RRRPPPPPIP

6.23

-7.75

-3.66

RTRRRPPPPP

6.38

-9.19

-5.10
P32381

LLTEPPMNPL

9.97

-9.21

-5.12

ILLTEPPMNP

10.60

-7.33

-3.24
Q00453

MPSAPIPLPH

9.05

-8.38

-4.29

LPHQPPPLPI

9.69

-9.83

-5.74

LYAPPYFPHP

10.69

-5.56

-1.47
P40021

VLNSPPLPPP

10.35

-8.49

-4.40

TKNTGPPPPL

11.33

-8.06

-3.97

GPPPPLPPPL

11.59

-9.03

-4.94
P36150

NPIVVNPSSP

14.25

-6.88

-2.79
Q12446

RRGPAPPPPP

6.16

-8.90

-4.81

RLPAPPPPPR

7.24

-10.13

-6.04

VRLPAPPPPP

7.51

-9.21

-5.12
Q01560

YYPPPPPGEH

8.93

-9.02

-4.93

HHQPPEPQPY

10.51

-5.04

-0.95

PQPYYPPPPP

10.51

-8.08

-3.99
P00950

RRSFDVPPPP

6.78

-6.20

-2.11

RSFDVPPPPI

10.56

-6.38

-2.29

SFDVPPPPID

14.23

-5.01

-0.92
P53735

KLVPPPPRTR

10.24

-8.86

-4.77

APKLVPPPPR

10.89

-10.03

-5.94

PKLVPPPPRT

11.11

-8.28

-4.19
P33334

MPTRFPPAVF

8.47

-10.18

-6.09

DLALPPPPPP

9.41

-7.82

-3.73

ALPPPPPPPP

9.72

-9.25

-5.16
P40523

VPVGVPPLAP

11.02

-7.04

-2.95

PLAPPPHGPF

11.39

-8.49

-4.40

VPPLAPPPHG

11.51

-7.97

-3.88
P40563

RRAPPPVPKK

7.62

-7.28

-3.19

KRRAPPPVPK

7.98

-8.50

-4.41

PKRRAPPPVP

8.72

-8.19

-4.10
Q08989

DHPKGPPPPP

7.22

-9.32

-5.23

HPKGPPPPPP

10.10

-8.75

-4.66

PKGPPPPPPP

10.19

-7.43

-3.34
P37370

NPTKSPPPPP

8.28

-9.74

-5.65

IPLAPLPPPP

8.81

-8.72

-4.63

VSQMPKPRPF

9.07

-6.64

-2.55
P39743

AYSNPLTSPV

12.34

-5.66

-1.57
Q03900

TPSGAPKLKN

13.56

-7.22

-3.13

HLPNTPSGAP

13.77

-7.89

-3.80

SHLPNTPSGA

14.18

-3.77

0.32

 


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