ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-7.PDB
Scoring matrix: MYO3_1ZUY-7_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.79
Foldx random average score for Saccharomyces cerevisiae: 10.479

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213455
Proteins after random average filtering: 7178
 Total fragments: 1356840
Proteins after disorder filtering: 4491
 Total fragments: 55313
Proteins after pattern filtering: 2015
 Total fragments: 9584
Proteins after MINT filtering: 24
 Total fragments: 454


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

12.79

2.48

0.00

Best peptides

MRPRPPWQ

0.00

-3.68

-6.16

         
Interactors      
P39113

RGPRRPQK

4.87

-1.93

-4.41

GPRRPQKN

6.73

-3.40

-5.88

APPPPPHK

8.35

-2.21

-4.69

P25604

LPPPPPPQ

7.21

-2.74

-5.22

KPKSPHLK

7.69

-1.38

-3.86

PLPPKPKS

8.15

-1.99

-4.47

P38822

PEVPPPRR

7.74

-2.39

-4.87

APEVPPPR

8.77

-2.69

-5.17

P40341

PPPKPPLN

7.57

-3.57

-6.05

KPPLNDPS

7.83

-1.53

-4.01

PPPPPPPK

8.55

-2.48

-4.96

Q08912

PPPPPPPD

8.98

-1.96

-4.44

PPPPPDEK

9.15

-1.53

-4.01

KGPPPPPP

9.20

-3.36

-5.84

P17555

PPPRPKKP

7.91

-4.09

-6.57

KSGPPPRP

8.25

-3.52

-6.00

APPPPPPA

8.58

-2.45

-4.93

Q12342

KAPPPPPP

9.23

-3.79

-6.27

KAKAPPPP

10.21

-2.66

-5.14

LETPSTPS

10.39

0.43

-2.05

P47068

PLPRAPPV

7.45

-1.21

-3.69

TAPPLPRA

8.22

-0.94

-3.42

APSPPPHQ

8.39

-2.46

-4.94

P04050

PPVRPSIS

6.78

-2.64

-5.12

LPVPPPPV

8.66

-2.16

-4.64

SPAYSPKQ

9.16

0.30

-2.18

P40450

PKLFPRLS

7.13

-2.74

-5.22

PPPLPDLF

8.10

-3.02

-5.50

SPKLFPRL

8.20

-1.62

-4.10

P40453

LRKRPPPP

6.70

-3.94

-6.42

RPPPPPPV

7.38

-2.41

-4.89

KPPDLPIR

7.41

-2.27

-4.75

P41832

PPPPPPMA

7.65

-2.88

-5.36

PPPVPAKL

8.48

-2.31

-4.79

PPPPMALF

8.51

-2.18

-4.66

P38237

PPNVPKKD

8.99

-2.67

-5.15

PPPNVPKK

9.52

-0.62

-3.10

QIPSKPEN

9.64

-0.52

-3.00

P53094

KLPPLPLT

5.92

-2.18

-4.66

PLPPQTRE

8.38

-1.75

-4.23

FPQSPIRA

8.51

-1.22

-3.70

Q01389

KPLPPQLL

6.94

-1.97

-4.45

RSKPLPPQ

7.60

-2.38

-4.86

REAPKPPA

8.10

-0.80

-3.28

P40021

PLPPPARS

7.51

-2.41

-4.89

PPLPPPLF

8.47

-2.47

-4.95

SPPLPPPA

8.53

-1.82

-4.30

Q04439

KPAPPPPG

7.02

-2.52

-5.00

KPKEPMFE

7.21

-2.74

-5.22

APPPPGMQ

7.86

-3.18

-5.66

Q12446

APPPPPRR

6.89

-2.75

-5.23

PPPRRGPA

6.96

-1.98

-4.46

LPQLPNRN

7.01

-3.71

-6.19

Q01560

YYPPPPPG

8.63

-2.20

-4.68

QEPQVPQE

8.72

-1.06

-3.54

QPPEPQPY

8.82

-1.38

-3.86

P00950

FDVPPPPI

9.12

-1.23

-3.71

DVPPPPID

9.55

-0.36

-2.84

PPPPIDAS

10.45

-0.11

-2.59

P33334

MPTRFPPA

4.54

-3.93

-6.41

PPPPPGFE

8.57

-2.81

-5.29

PPPPPGYE

8.63

-2.17

-4.65

P40523

PLAPPPHG

8.58

-2.40

-4.88

PVGVPPLA

8.80

-1.96

-4.44

PGTVPNMQ

8.86

-2.31

-4.79

Q08989

PPPPPPPD

8.98

-1.96

-4.44

PPPPPDEK

9.15

-1.53

-4.01

KGPPPPPP

9.20

-3.36

-5.84

P37370

MPKPRPFQ

5.83

-4.66

-7.14

PKPRPFQN

5.90

-2.69

-5.17

KSPPPPPS

7.07

-1.65

-4.13

 


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