ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-29.PDB
Scoring matrix: MYO3_1ZUY-29_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.36
Foldx random average score for Saccharomyces cerevisiae: 13.502

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199099
Proteins after random average filtering: 7178
 Total fragments: 1323927
Proteins after disorder filtering: 3875
 Total fragments: 36150
Proteins after pattern filtering: 1770
 Total fragments: 6378
Proteins after MINT filtering: 25
 Total fragments: 182


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.36

-1.50

0.00

Best peptides

DRWPRPPRWH

0.00

-6.82

-5.32

         
Interactors      
P39113

PRRPQKNRYN

7.31

-5.40

-3.90

HRGPRRPQKN

8.49

-5.45

-3.95

SASHRGPRRP

9.99

-5.24

-3.74

P36150

PIVVNPSSPS

12.61

-5.95

-4.45

P38822

APEVPPPRRS

10.14

-7.60

-6.10

DRGPAPEVPP

12.85

-4.65

-3.15

P40341

SRNIPPPPPP

12.81

-5.34

-3.84

Q08912

GDHPKGPPPP

13.21

-3.07

-1.57

P17555

SKSGPPPRPK

9.13

-7.52

-6.02

GPPPRPKKPS

11.45

-4.05

-2.55

PPRPKKPSTL

12.04

-3.36

-1.86

P25604

SPHLKPPLPP

10.59

-5.98

-4.48

PPKPKSPHLK

11.67

-5.25

-3.75

PKSPHLKPPL

11.95

-4.64

-3.14

P47068

DPSSNPFFRK

10.89

-6.48

-4.98

KYYVPPGIPT

10.99

-4.44

-2.94

EYHPMPNTAP

11.48

-3.92

-2.42

P04050

TCLPVPPPPV

11.27

-7.25

-5.75

PVRPSISFNE

11.46

-5.23

-3.73

NYSPTSPSYS

12.61

-1.52

-0.02

P40450

SPKLFPRLSS

11.16

-4.93

-3.43

SSSPKLFPRL

12.25

-4.69

-3.19

SVSSSPKLFP

12.69

-5.14

-3.64

P40453

PDLPIRLRKR

7.37

-7.69

-6.19

IRLRKRPPPP

8.73

-7.23

-5.73

RLRKRPPPPP

9.30

-7.35

-5.85

P41832

GVIPPAPPMM

13.08

-6.19

-4.69

Q12342

AKAPPPPPPP

13.21

-6.52

-5.02

RKAKAPPPPP

13.35

-6.08

-4.58

P38237

ENFQIPSKPE

9.17

-7.45

-5.95

LNDPFVPPPN

12.59

-3.83

-2.33

P53094

YPLKLPPLPL

10.16

-7.85

-6.35

DEDPVSPKPV

10.66

-4.19

-2.69

PVSPKPVSKS

10.67

-5.17

-3.67

Q01389

REAPKPPANT

11.72

-4.85

-3.35

PKREAPKPPA

11.99

-5.16

-3.66

RRYPQTPSYY

12.24

-3.62

-2.12

P40021

PPLPPPARSQ

10.74

-6.83

-5.33

NYVISPNLPT

11.07

-4.74

-3.24

SLDFLPSTPS

11.11

-6.34

-4.84

Q04439

SRHSKKPAPP

10.03

-4.77

-3.27

SSKPKEPMFE

10.32

-5.54

-4.04

SKKPAPPPPG

11.44

-6.40

-4.90

Q12446

PKHSLPPLPN

8.59

-7.28

-5.78

QNRPLPQLPN

9.96

-7.54

-6.04

NRNNRPVPPP

10.11

-6.64

-5.14

Q01560

PPEPQPYYPP

12.39

-6.54

-5.04

PYYPPPPPGE

12.65

-4.49

-2.99

P00950

RSFDVPPPPI

12.81

-5.78

-4.28

P33334

SKMPTRFPPA

11.60

-6.28

-4.78

SDLALPPPPP

11.62

-6.21

-4.71

EELDNPMVPS

12.86

-5.74

-4.24

P40523

HNSPRNPDTG

12.16

-2.71

-1.21

PPGTVPNMQM

12.69

-6.48

-4.98

NITPLPTPVP

13.31

-4.45

-2.95

Q08989

GDHPKGPPPP

13.21

-3.07

-1.57

P37370

SQMPKPRPFQ

9.07

-7.71

-6.21

VPQNRPHMPS

10.03

-4.76

-3.26

MPKPRPFQNK

10.80

-4.43

-2.93

 


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