ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-9.PDB
Scoring matrix: MYO3_1YP5-9_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.61
Foldx random average score for Saccharomyces cerevisiae: 10.814

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213455
Proteins after random average filtering: 7178
 Total fragments: 1711014
Proteins after disorder filtering: 4451
 Total fragments: 56538
Proteins after pattern filtering: 1892
 Total fragments: 5580
Proteins after MINT filtering: 20
 Total fragments: 174


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.61

1.02

0.00

Best peptides

RRWRPPRK

0.00

-6.38

-7.40

         
Interactors      
P47068

PLPRAPPV

7.79

-3.73

-4.75

RAPPVPPA

9.01

-3.50

-4.52

PEPISPET

9.24

-2.49

-3.51

P39113

RGPRRPQK

4.92

-4.13

-5.15

HRGPRRPQ

8.83

-2.27

-3.29

FTHPEGPN

10.46

-0.60

-1.62

Q01389

RYPQTPSY

7.44

-2.59

-3.61

EAPKPPAN

7.65

-3.53

-4.55

RSKPLPPQ

8.46

-3.13

-4.15

P04050

FSPTSPTY

9.15

-2.07

-3.09

YSPTSPSY

9.73

-2.15

-3.17

YSPTSPAY

9.81

-1.96

-2.98

P40523

PVGVPPLA

8.53

-4.17

-5.19

PLPTPVPV

8.81

-3.72

-4.74

PGTVPNMQ

8.99

-3.48

-4.50

P38237

QIPSKPEN

9.71

-1.91

-2.93

FQIPSKPE

10.09

-2.46

-3.48

PFVPPPNV

10.11

-2.16

-3.18

P40450

PKLFPRLS

8.86

-3.35

-4.37

AAPAPPPL

9.59

-2.72

-3.74

SSPKLFPR

10.07

-2.76

-3.78

P40453

KVPEPPSW

7.70

-3.33

-4.35

DCPRCGPT

9.05

-1.18

-2.20

PSWKPPDL

9.48

-3.05

-4.07

P38822

PEVPPPRR

8.17

-4.30

-5.32

P41832

ETPPPPPL

9.92

-2.38

-3.40

VIPPAPPM

10.27

-2.96

-3.98

P53094

LKLPPLPL

7.67

-2.72

-3.74

KLPPLPLT

7.92

-3.09

-4.11

LNVPLPPQ

8.90

-2.76

-3.78

Q04439

NIPTPPQN

7.79

-4.21

-5.23

SKPKEPMF

7.82

-3.61

-4.63

ARPSPPTA

8.67

-3.01

-4.03

P37370

PKPRPFQN

5.64

-4.65

-5.67

QMPKPRPF

6.43

-5.76

-6.78

PSINPPKQ

8.07

-2.67

-3.69

P40021

PLPPPARS

8.02

-4.87

-5.89

FLPSTPSQ

8.53

-2.02

-3.04

ISPNLPTT

10.40

-0.97

-1.99

Q12446

PFPVPQQQ

7.59

-4.25

-5.27

SAPIPPTL

8.11

-3.67

-4.69

PFPFPVPQ

8.12

-2.90

-3.92

Q01560

YYPPPPPG

8.83

-5.41

-6.43

PQEPPAPQ

9.27

-2.16

-3.18

QEPQVPQE

9.38

-2.43

-3.45

P17555

PRPKKPST

8.34

-3.46

-4.48

PKKPSTLK

10.27

-2.07

-3.09

SGPPPRPK

10.38

-2.11

-3.13

P00950

FDVPPPPI

8.10

-2.99

-4.01

DVPPPPID

10.24

-2.92

-3.94

P33334

FDPSLNPI

9.64

-0.97

-1.99

DNPMVPSS

10.09

-1.97

-2.99

GLPPPPPG

10.20

-4.52

-5.54

P25604

PKPKSPHL

8.37

-2.81

-3.83

QAPSLPPK

9.08

-1.60

-2.62

PLPPKPKS

9.27

-3.93

-4.95

 


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