ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-6.PDB
Scoring matrix: MYO3_1YP5-6_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 13.47
Foldx random average score for Saccharomyces cerevisiae: 13.209

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199099
Proteins after random average filtering: 7178
 Total fragments: 1514410
Proteins after disorder filtering: 4611
 Total fragments: 110137
Proteins after pattern filtering: 2264
 Total fragments: 16983
Proteins after MINT filtering: 26
 Total fragments: 959


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

13.47

3.51

0.00

Best peptides

HRRMGWMRPR

0.00

-4.66

-8.17

         
Interactors      
P39113

ASHRGPRRPQ

5.65

-3.77

-7.28

MSPLGAPPPP

8.48

-1.65

-5.16

THPEGPNCTN

9.61

-1.04

-4.55

P36150

PIVVNPSSPS

11.46

1.16

-2.35

P38822

DRGPAPEVPP

9.43

0.63

-2.88

APEVPPPRRS

10.03

-2.95

-6.46

RGPAPEVPPP

12.37

-1.27

-4.78

P40341

KPPLNDPSNP

9.35

1.33

-2.18

IPPPPPPPPP

9.98

-3.96

-7.47

NNSRNIPPPP

10.19

1.82

-1.69

Q08912

TPSWGPSPMG

8.28

-2.83

-6.34

DHPKGPPPPP

9.64

-1.91

-5.42

CYTPSWGPSP

9.75

-0.95

-4.46

P17555

PKKPSTLKTK

8.95

-1.89

-5.40

KSGPPPRPKK

9.83

-2.51

-6.02

SKSGPPPRPK

10.34

-0.38

-3.89

P25604

HLKPPLPPPP

8.87

-2.14

-5.65

PKPKSPHLKP

9.61

-1.96

-5.47

PKSPHLKPPL

9.70

0.36

-3.15

P47068

HPMPNTAPPL

7.67

-0.73

-4.24

HPVPSAPSAP

7.88

-0.50

-4.01

MPNTAPPLPR

8.45

-3.14

-6.65

P04050

GYSPGSPAYS

9.16

-1.06

-4.57

SPNYSPTSPS

9.66

-0.25

-3.76

SPGFSPTSPT

9.78

-0.27

-3.78

P40450

PPLPNGLLSS

9.17

0.20

-3.31

LPQLPPPPPP

9.90

-3.92

-7.43

LPPPPPPPPP

10.03

-4.14

-7.65

P40453

KPPDLPIRLR

8.80

-1.10

-4.61

SWKPPDLPIR

9.15

-2.82

-6.33

MPTTPEIPPP

9.18

-3.70

-7.21

P41832

PPLPSVLSSS

9.03

-2.20

-5.71

IPPAPPMMPA

9.82

-3.91

-7.42

TPPPPPLPSV

10.19

-2.84

-6.35

Q12342

RKAKAPPPPP

8.80

-2.16

-5.67

LETPSTPSDG

10.49

0.06

-3.45

KAPPPPPPPP

11.17

-1.49

-5.00

P38237

PFVPPPNVPK

9.86

-1.83

-5.34

IPSKPENTVN

10.45

-3.70

-7.21

DPDLNDPFVP

10.95

1.13

-2.38

P53094

AFPQSPIRAY

7.83

-2.14

-5.65

TREPNEPPPP

9.47

0.54

-2.97

VPLPPQTREP

9.91

-1.84

-5.35

Q01389

IPSPSSSPPP

8.35

-2.07

-5.58

KPLPPQLLSS

9.02

-3.08

-6.59

PKREAPKPPA

9.29

-2.08

-5.59

P40021

TKNTGPPPPL

8.35

-2.57

-6.08

PPLPPPARSQ

9.79

-2.58

-6.09

PPLPPPLFPS

10.30

-3.11

-6.62

Q04439

IPTPPQNRDV

7.59

-2.31

-5.82

PPPPGMQNKA

8.71

-3.46

-6.97

SKKPAPPPPG

9.10

-0.96

-4.47

Q12446

PPRRGPAPPP

6.93

-4.49

-8.00

RRGPAPPPPP

8.08

-1.73

-5.24

HPKHSLPPLP

8.37

-1.53

-5.04

Q01560

PPPPGEHMHG

7.57

-3.47

-6.98

YYPPPPPGEH

10.41

-4.19

-7.70

VPPPSNAPIY

10.46

-2.17

-5.68

P00950

RRSFDVPPPP

10.95

1.78

-1.73

SFDVPPPPID

11.36

-2.11

-5.62

VPPPPIDASS

12.06

-1.59

-5.10

P33334

FFDPSLNPIP

7.46

-2.36

-5.87

PPPPGFEEDS

7.62

-2.61

-6.12

PPPPGYEIEE

7.90

-2.48

-5.99

P40523

YMHNSPRNPD

8.72

-4.33

-7.84

PPPHGPFSTS

8.73

-3.07

-6.58

GAPPGTVPNM

9.62

-2.46

-5.97

Q08989

DHPKGPPPPP

9.64

-1.91

-5.42

HPKGPPPPPP

10.61

-2.65

-6.16

PPPPPDEKGR

10.72

-1.57

-5.08

P37370

RPHMPSVRPA

6.83

-3.63

-7.14

PPIPGAVPSV

7.55

-3.56

-7.07

PPPPGAFSTS

8.02

-3.38

-6.89

P39743

PAYSNPLTSP

12.21

2.46

-1.05

YSNPLTSPVA

12.82

0.51

-3.00

 


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