ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-27.PDB
Scoring matrix: MYO3_1YP5-27_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 8.8
Foldx random average score for Saccharomyces cerevisiae: 10.440

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206277
Proteins after random average filtering: 7178
 Total fragments: 1816954
Proteins after disorder filtering: 4711
 Total fragments: 133538
Proteins after pattern filtering: 2296
 Total fragments: 20362
Proteins after MINT filtering: 26
 Total fragments: 1055


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

8.80

-3.75

0.00

Best peptides

WDPRWDPRR

0.00

-5.38

-1.63

         
Interactors      
P39113

LGAPPPPPH

3.04

-6.19

-2.44

RGPRRPQKN

3.85

-5.33

-1.58

LFTHPEGPN

4.98

-5.03

-1.28

P36150

IVVNPSSPS

6.45

-4.65

-0.90

P38822

RGPAPEVPP

4.92

-5.42

-1.67

APEVPPPRR

6.51

-6.45

-2.70

GPAPEVPPP

7.32

-3.56

0.19

P40341

RNIPPPPPP

2.66

-6.07

-2.32

IPPPPPPPP

3.37

-6.58

-2.83

NIPPPPPPP

5.22

-5.71

-1.96

Q08912

KGPPPPPPP

3.60

-6.37

-2.62

GPPPPPPPD

4.95

-5.69

-1.94

HPKGPPPPP

5.60

-5.32

-1.57

P17555

KSGPPPRPK

4.69

-5.31

-1.56

AAPAPPPPP

4.73

-5.94

-2.19

APAPPPPPP

4.93

-5.44

-1.69

P25604

LKPPLPPPP

3.72

-6.12

-2.37

LPPKPKSPH

4.19

-5.05

-1.30

LPPPPPPQP

4.73

-5.67

-1.92

P47068

LSAPSIPPV

4.35

-3.88

-0.13

LSAPSVPPV

4.49

-3.87

-0.12

LPEPISPET

5.10

-4.22

-0.47

P04050

LPVPPPPVR

5.09

-4.71

-0.96

VPPPPVRPS

5.78

-5.08

-1.33

GSPAYSPKQ

6.61

-4.01

-0.26

P40450

LPPPPPPPP

2.94

-6.59

-2.84

LVTPPAPPL

4.12

-5.54

-1.79

VPPPPPPPP

4.57

-5.65

-1.90

P40453

LRKRPPPPP

2.21

-6.82

-3.07

RKRPPPPPP

2.52

-6.36

-2.61

WKPPDLPIR

2.99

-5.78

-2.03

P41832

LSSQPPPPP

3.95

-6.44

-2.69

APPPPPPPP

4.54

-5.78

-2.03

QPPPPPPPP

4.77

-5.81

-2.06

Q12342

RKAKAPPPP

3.94

-4.46

-0.71

KAKAPPPPP

4.28

-6.48

-2.73

KAPPPPPPP

4.29

-6.18

-2.43

P38237

LNDPFVPPP

4.01

-4.52

-0.77

FQIPSKPEN

5.58

-3.19

0.56

FVPPPNVPK

6.12

-5.53

-1.78

P53094

LKLPPLPLT

4.54

-5.56

-1.81

REPNEPPPP

5.62

-4.59

-0.84

EPNEPPPPC

5.68

-4.55

-0.80

Q01389

KREAPKPPA

3.67

-6.66

-2.91

KRSKPLPPQ

4.09

-6.09

-2.34

RSKPLPPQL

5.63

-3.59

0.16

P40021

LNSPPLPPP

3.18

-5.72

-1.97

KNTGPPPPL

5.06

-5.58

-1.83

GPPPPLPPP

5.10

-5.43

-1.68

Q04439

IPPPPPPPP

3.37

-6.58

-2.83

KKPAPPPPG

3.61

-7.21

-3.46

RHSKKPAPP

3.93

-3.88

-0.13

Q12446

RGPAPPPPP

2.16

-6.60

-2.85

RLPAPPPPP

2.84

-6.58

-2.83

RNNRPVPPP

3.01

-5.39

-1.64

Q01560

APQEPPAPQ

5.81

-3.80

-0.05

APDAPQEPQ

6.43

-5.17

-1.42

QHHQPPEPQ

6.47

-4.98

-1.23

P00950

FDVPPPPID

3.50

-5.37

-1.62

RSFDVPPPP

5.61

-4.96

-1.21

VPPPPIDAS

8.59

-3.21

0.54

P33334

LPPPPPPPP

2.94

-6.59

-2.84

LPPPPPPPS

3.07

-6.70

-2.95

LPPPPPPPG

3.09

-6.78

-3.03

P40523

MHNSPRNPD

4.85

-5.19

-1.44

LAPPPHGPF

4.92

-4.66

-0.91

VGVPPLAPP

5.51

-4.70

-0.95

Q08989

KGPPPPPPP

3.60

-6.37

-2.62

GPPPPPPPP

4.88

-5.72

-1.97

HPKGPPPPP

5.60

-5.32

-1.57

P37370

MPAPPPPPP

3.14

-6.74

-2.99

IPLAPLPPP

3.67

-6.38

-2.63

LEKPPSPPV

4.14

-5.40

-1.65

P39743

YSNPLTSPV

9.01

-3.32

0.43

AYSNPLTSP

10.03

-2.34

1.41

 


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