ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-21.PDB
Scoring matrix: MYO3_1YP5-21_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 16.35
Foldx random average score for Saccharomyces cerevisiae: 14.993

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199099
Proteins after random average filtering: 7178
 Total fragments: 1915561
Proteins after disorder filtering: 4469
 Total fragments: 76965
Proteins after pattern filtering: 1650
 Total fragments: 4010
Proteins after MINT filtering: 19
 Total fragments: 126


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

16.35

1.44

0.00

Best peptides

EEKMGRPTMT

0.00

-2.47

-3.91

         
Interactors      
Q12446

RPLPQLPNRN

9.60

-3.31

-4.75

PEIPSTQSAT

12.04

-1.10

-2.54

FPIPEIPSTQ

12.43

-0.36

-1.80

P47068

PEPISPETKK

8.44

-3.52

-4.96

YVPPGIPTND

12.86

-0.73

-2.17

LPEPISPETK

13.39

-1.02

-2.46

P39113

HRGPRRPQKN

9.42

-0.68

-2.12

PEGPNCTNTN

10.91

-2.82

-4.26

PRRPQKNRYN

11.88

-0.27

-1.71

Q01389

RSKPLPPQLL

8.62

-2.51

-3.95

REAPKPPANT

10.97

-1.61

-3.05

RRYPQTPSYY

11.63

0.02

-1.42

P04050

GFSPTSPTYS

11.09

-1.21

-2.65

GEAPTSPGFG

11.82

-0.61

-2.05

SYSPTSPNYS

12.14

-1.88

-3.32

P40523

PHGPFSTSML

12.00

-1.07

-2.51

GGPLASPTHY

13.27

-3.23

-4.67

APPGTVPNMQ

13.63

-3.66

-5.10

P38237

FQIPSKPENT

12.57

-0.16

-1.60

PSKPENTVNL

12.74

-0.33

-1.77

VPPPNVPKKD

12.76

-3.02

-4.46

P40450

PPLPDLFKTK

11.98

-1.33

-2.77

SSPKLFPRLS

12.07

-1.96

-3.40

PPLPESLSMN

12.96

-2.73

-4.17

P40453

PDLPIRLRKR

10.30

-2.15

-3.59

WKPPDLPIRL

11.94

-0.42

-1.86

TKVPEPPSWK

12.27

-1.96

-3.40

P53094

LNVPLPPQTR

12.00

-1.43

-2.87

SAFPQSPIRA

12.39

-2.17

-3.61

AKAPNTPSTS

13.05

-1.03

-2.47

P40021

VISPNLPTTI

12.27

-1.53

-2.97

ISPNLPTTIT

12.62

-0.89

-2.33

PSTPSQMNYD

12.64

-1.11

-2.55

Q04439

SSKPKEPMFE

9.65

-1.57

-3.01

PPPPGMQNKA

12.53

-3.71

-5.15

NNIPTPPQNR

13.01

-2.04

-3.48

P37370

QNRPHMPSVR

11.42

-1.59

-3.03

KATPVPPTLA

11.91

-2.20

-3.64

SPSINPPKQS

11.93

-3.54

-4.98

P40341

LNDPSNPVSK

13.40

-1.26

-2.70

Q01560

PQEPQVPQES

12.19

0.19

-1.25

PPAPQEQNDV

14.20

-1.70

-3.14

PPPPGEHMHG

14.45

-2.98

-4.42

P17555

PKKPSTLKTK

9.59

-2.45

-3.89

PRPKKPSTLK

11.76

-1.29

-2.73

PPRPKKPSTL

12.55

-1.24

-2.68

P25604

PPKPKSPHLK

10.03

-2.63

-4.07

PPQPASNALD

13.54

-2.91

-4.35

PPKPNTQLQQ

14.84

-0.51

-1.95

P33334

NAIPGGPKFE

10.45

-1.94

-3.38

MPTRFPPAVF

13.47

-1.98

-3.42

PMVPSSVNED

13.77

-0.51

-1.95

Q12342

LETPSTPSDG

13.05

-0.98

-2.42

 


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