ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-20.PDB
Scoring matrix: MYO3_1YP5-20_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.4
Foldx random average score for Saccharomyces cerevisiae: 17.256

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206277
Proteins after random average filtering: 7178
 Total fragments: 1420192
Proteins after disorder filtering: 4465
 Total fragments: 63423
Proteins after pattern filtering: 2007
 Total fragments: 7731
Proteins after MINT filtering: 22
 Total fragments: 247


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.40

-1.80

0.00

Best peptides

MMFLHGRHY

0.00

-7.35

-5.55

         
Interactors      
P39113

PPPPHKDHL

9.54

-6.97

-5.17

HRGPRRPQK

11.80

-5.26

-3.46

PRRPQKNRY

13.04

-5.61

-3.81

P25604

PPKPKSPHL

8.60

-7.36

-5.56

LPPKPNTQL

13.12

-7.07

-5.27

KPKSPHLKP

14.47

-6.53

-4.73

P53094

CYPLKLPPL

14.61

-6.38

-4.58

LPPLPLTSD

14.62

-5.80

-4.00

DEDPVSPKP

15.11

-3.80

-2.00

P40341

KPPLNDPSN

14.36

-6.51

-4.71

PPPPPKPPL

16.91

-6.94

-5.14

PPKPPLNDP

17.06

-6.00

-4.20

P17555

RPKKPSTLK

12.93

-8.01

-6.21

SGPPPRPKK

13.52

-5.18

-3.38

PPAPPASVF

15.90

-6.61

-4.81

Q08912

GDHPKGPPP

15.22

-5.96

-4.16

PPPPPDEKD

15.30

-3.42

-1.62

YTPSWGPSP

16.13

-3.63

-1.83

P47068

APPLPRAPP

12.78

-7.26

-5.46

YHPMPNTAP

13.65

-6.14

-4.34

DKVPPHPVP

15.04

-6.74

-4.94

P04050

PPPPVRPSI

13.73

-5.94

-4.14

SYSPTSPNY

13.95

-3.19

-1.39

NYSPTSPSY

14.46

-3.68

-1.88

P40450

PPPLPDLFK

12.13

-7.43

-5.63

SSPKLFPRL

12.82

-4.46

-2.66

APPLPNGLL

14.03

-7.09

-5.29

P40453

PDLPIRLRK

13.10

-3.24

-1.44

VPEPPSWKP

13.36

-6.58

-4.78

PPDLPIRLR

13.75

-6.57

-4.77

P41832

PPPPPMALF

15.41

-6.83

-5.03

PPPPMALFG

15.71

-4.46

-2.66

PPPLPSVLS

16.70

-5.17

-3.37

P38237

IPSKPENTV

15.06

-5.14

-3.34

VPPPNVPKK

16.04

-5.64

-3.84

Q01389

RRYPQTPSY

13.87

-5.26

-3.46

RPVPPDSSY

14.16

-7.09

-5.29

EEAPTKPNP

15.36

-4.79

-2.99

P40021

SHPPNHPHS

11.79

-3.75

-1.95

PSTPSQMNY

15.54

-3.35

-1.55

PLPPPARSQ

16.47

-4.22

-2.42

Q04439

PPPPPSSKP

13.64

-6.85

-5.05

APPPPGMQN

14.07

-4.96

-3.16

HSKKPAPPP

14.83

-6.49

-4.69

Q12446

PPPPPHRHV

8.09

-8.78

-6.98

LPQLPNRNN

10.97

-7.99

-6.19

PPPRRGPAP

11.55

-8.50

-6.70

Q01560

PPPPPGEHM

7.65

-8.54

-6.74

HHQPPEPQP

14.78

-4.58

-2.78

QPPEPQPYY

15.64

-5.87

-4.07

P33334

NAIPGGPKF

11.01

-5.23

-3.43

PSLNPIPHF

12.09

-4.23

-2.43

LFFDPSLNP

13.56

-3.16

-1.36

P40523

APPPHGPFS

12.04

-3.69

-1.89

LGAPPGTVP

14.05

-6.43

-4.63

VPVPVGVPP

14.52

-5.68

-3.88

Q08989

GDHPKGPPP

15.22

-5.96

-4.16

PPPPPDEKG

16.41

-4.60

-2.80

PPPPDEKGR

16.83

-4.72

-2.92

P37370

KVPQNRPHM

7.42

-7.15

-5.35

QMPKPRPFQ

9.71

-5.97

-4.17

RPHMPSVRP

10.29

-8.43

-6.63

P39743

NATIPEDNP

14.21

-5.36

-3.56

SNPLTSPVA

17.10

-3.33

-1.53

 


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