ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-17.PDB
Scoring matrix: MYO3_1YP5-17_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.52
Foldx random average score for Saccharomyces cerevisiae: 15.273

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206277
Proteins after random average filtering: 7178
 Total fragments: 1418525
Proteins after disorder filtering: 4449
 Total fragments: 61420
Proteins after pattern filtering: 1980
 Total fragments: 7033
Proteins after MINT filtering: 21
 Total fragments: 222


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.52

-2.98

0.00

Best peptides

RMFMRRRRY

0.00

-8.46

-5.48

         
Interactors      
P47068

NTAPPLPRA

11.89

-1.73

1.25

PSSNPFFRK

12.80

-1.11

1.87

PHVPSLTNR

13.04

-2.71

0.27

P39113

GPRRPQKNR

10.83

-5.33

-2.35

PRRPQKNRY

10.94

-5.45

-2.47

HRGPRRPQK

11.21

-3.99

-1.01

Q01389

RPVPPDSSY

9.70

-8.83

-5.85

RRYPQTPSY

10.26

-5.89

-2.91

YPQTPSYYY

10.86

-6.28

-3.30

P04050

PPPPVRPSI

11.02

-6.04

-3.06

PPVRPSISF

12.08

-4.81

-1.83

SYSPTSPNY

12.52

-4.02

-1.04

P40523

LGAPPGTVP

12.17

-5.17

-2.19

APPPHGPFS

12.26

-2.77

0.21

LAPPPHGPF

14.01

-5.35

-2.37

P38237

VPPPNVPKK

12.86

-4.93

-1.95

FQIPSKPEN

13.67

-1.98

1.00

IPSKPENTV

14.47

-6.26

-3.28

P40450

PPLPNGLLS

13.16

-3.06

-0.08

SSPKLFPRL

13.41

-3.45

-0.47

PPLPDLFKT

13.76

-2.61

0.37

P40453

PDLPIRLRK

9.76

-3.56

-0.58

WKPPDLPIR

10.82

-5.22

-2.24

VPEPPSWKP

12.70

-5.41

-2.43

Q08989

PPPPDEKGR

12.97

-4.40

-1.42

PPPPPDEKG

14.29

-3.20

-0.22

P41832

PPPPPMALF

12.40

-6.00

-3.02

PPPPPVPAK

13.80

-4.84

-1.86

PPPPPLPSV

13.88

-4.65

-1.67

P53094

FPQSPIRAY

10.52

-5.46

-2.48

SAFPQSPIR

12.29

-2.74

0.24

VPLPPQTRE

12.62

-4.24

-1.26

Q04439

APPPPGMQN

10.60

-4.51

-1.53

IPTPPQNRD

12.28

-4.91

-1.93

RPSPPTAAT

12.86

-6.00

-3.02

P37370

RPHMPSVRP

7.76

-9.04

-6.06

KVPQNRPHM

8.63

-5.14

-2.16

RPSPISPSI

10.04

-7.42

-4.44

P40021

LPSTPSQMN

11.89

-3.85

-0.87

PSTPSQMNY

13.37

-4.37

-1.39

PLPPPARSQ

13.58

-3.89

-0.91

Q12446

RPLPQLPNR

8.23

-7.65

-4.67

PPPPPHRHV

9.16

-6.27

-3.29

PPPPPRASR

10.15

-5.05

-2.07

Q01560

PPPPPGEHM

8.73

-7.24

-4.26

QPPEPQPYY

11.17

-6.30

-3.32

PPPPGEHMH

13.92

-5.82

-2.84

P39743

NATIPEDNP

13.94

-3.16

-0.18

Q08912

PPPPPDEKD

13.36

-2.56

0.42

YTPSWGPSP

13.37

-2.77

0.21

PPPPDEKDR

13.50

-3.69

-0.71

P17555

RPKKPSTLK

10.07

-6.90

-3.92

SGPPPRPKK

11.08

-4.80

-1.82

PPAPPASVF

12.95

-5.46

-2.48

P33334

NAIPGGPKF

9.62

-3.85

-0.87

PPPPPGYEI

10.66

-4.92

-1.94

NNAIPGGPK

12.05

-2.63

0.35

P25604

PPKPKSPHL

10.39

-4.61

-1.63

KPKSPHLKP

12.72

-5.00

-2.02

LPPKPNTQL

12.97

-7.03

-4.05

 


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