ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-15.PDB
Scoring matrix: MYO3_1YP5-15_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.82
Foldx random average score for Saccharomyces cerevisiae: 10.742

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206277
Proteins after random average filtering: 7178
 Total fragments: 1453167
Proteins after disorder filtering: 4170
 Total fragments: 41912
Proteins after pattern filtering: 1801
 Total fragments: 5902
Proteins after MINT filtering: 23
 Total fragments: 182


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.82

4.85

0.00

Best peptides

RPFVIWKTR

0.00

-4.57

-9.42

         
Interactors      
P39113

HRGPRRPQK

7.38

0.26

-4.59

GPRRPQKNR

7.67

-2.09

-6.94

PPPPHKDHL

9.66

-1.94

-6.79

P25604

LPPKPNTQL

7.20

-3.60

-8.45

PKPKSPHLK

9.08

-0.52

-5.37

SLPPKPNTQ

9.78

0.06

-4.79

P38822

APEVPPPRR

6.64

-2.74

-7.59

P40341

NDPSNPVSK

9.85

2.59

-2.26

P17555

RPKKPSTLK

7.18

-1.53

-6.38

PRPKKPSTL

9.21

-1.22

-6.07

PPPAPPASV

10.50

0.13

-4.72

Q08912

TPSWGPSPM

9.28

-1.64

-6.49

PPPPDEKDR

9.68

-1.81

-6.66

PPPPPPDEK

10.61

-2.30

-7.15

P47068

PEPISPETK

8.61

-0.55

-5.40

MPFVDPSSN

8.76

-2.34

-7.19

APPVPPATF

8.93

-1.03

-5.88

P04050

PPPPVRPSI

7.80

-1.15

-6.00

LPVPPPPVR

7.99

-0.87

-5.72

CLPVPPPPV

9.39

-1.70

-6.55

P40450

APPLPNGLL

8.52

-3.67

-8.52

PPLPESLSM

8.92

-0.79

-5.64

PPPLPQSLL

9.13

-3.62

-8.47

P40453

WKPPDLPIR

7.40

-0.30

-5.15

PPDLPIRLR

7.88

-1.92

-6.77

IPPPLPPKI

8.41

-1.03

-5.88

P41832

VIPPAPPMM

9.23

-0.96

-5.81

PPPPPLPSV

9.23

-1.42

-6.27

PPPPVPAKL

9.54

-1.67

-6.52

P38237

IPSKPENTV

8.82

-1.40

-6.25

DPFVPPPNV

9.13

-1.23

-6.08

VPPPNVPKK

10.07

-1.22

-6.07

Q01389

RYPQTPSYY

7.88

0.92

-3.93

SPSYPSIFR

8.66

-0.92

-5.77

RTEPSTPSR

8.70

0.12

-4.73

P40021

HPPNHPHSQ

6.40

-0.53

-5.38

FLPSTPSQM

7.36

-1.00

-5.85

SPPLPPPAR

8.67

-2.08

-6.93

Q08989

PPPPDEKGR

9.83

-2.10

-6.95

PPPPPPDEK

10.61

-2.30

-7.15

Q04439

NIPTPPQNR

6.81

-1.51

-6.36

KPAPPPPGM

8.41

-2.98

-7.83

KPKEPMFEA

9.55

0.17

-4.68

Q12446

RPLPQLPNR

5.61

-1.45

-6.30

PPPPPRASR

6.97

-3.45

-8.30

LPPASPEVR

7.35

-1.90

-6.75

Q01560

EPQVPQESA

9.42

-0.61

-5.46

PPPPPGEHM

9.85

-2.66

-7.51

VPPPSNAPI

10.65

-1.58

-6.43

P00950

SFDVPPPPI

10.35

-1.13

-5.98

P33334

MPTRFPPAV

7.25

-1.85

-6.70

FFDPSLNPI

9.19

0.06

-4.79

DNPMVPSSV

9.66

1.05

-3.80

P40523

PGTVPNMQM

9.33

-1.24

-6.09

PPGTVPNMQ

9.60

-1.02

-5.87

APPGTVPNM

9.93

-0.86

-5.71

P53094

NVPLPPQTR

7.07

0.02

-4.83

CYPLKLPPL

8.74

-3.06

-7.91

LPPLPLTSD

8.76

-1.83

-6.68

P37370

KVPQNRPHM

5.54

-4.58

-9.43

RPSPISPSI

7.16

0.02

-4.83

NRPHMPSVR

7.23

0.22

-4.63

 


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