ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-13.PDB
Scoring matrix: MYO3_1YP5-13_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.17
Foldx random average score for Saccharomyces cerevisiae: 11.442

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213455
Proteins after random average filtering: 7178
 Total fragments: 1365095
Proteins after disorder filtering: 4307
 Total fragments: 50019
Proteins after pattern filtering: 1986
 Total fragments: 8775
Proteins after MINT filtering: 21
 Total fragments: 390


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.17

-0.66

0.00

Best peptides

RPPFPYWR

0.00

-7.98

-7.32

         
Interactors      
Q12446

LPQLPNRN

6.41

-7.07

-6.41

LPPLPNQF

6.64

-6.70

-6.04

APPPPPRR

7.07

-6.41

-5.75

P47068

PPHVPSLT

8.13

-4.71

-4.05

DPSSNPFF

8.65

-4.84

-4.18

PSSNPFFR

8.88

-3.73

-3.07

P39113

RGPRRPQK

8.20

-4.90

-4.24

GPRRPQKN

9.60

-6.04

-5.38

APPPPPHK

9.63

-5.67

-5.01

Q01389

SPSYPSIF

7.58

-5.94

-5.28

SKPLPPQL

7.80

-5.29

-4.63

YPQTPSYY

7.96

-6.24

-5.58

P04050

PPVRPSIS

7.99

-6.35

-5.69

SPTSPSYS

8.78

-4.65

-3.99

SPTSPTYS

8.82

-4.24

-3.58

P40523

PPPHGPFS

8.82

-4.73

-4.07

PVGVPPLA

9.76

-3.78

-3.12

PLAPPPHG

10.85

-4.66

-4.00

P38237

IPSKPENT

8.35

-5.48

-4.82

NFQIPSKP

10.13

-5.28

-4.62

DPFVPPPN

10.65

-4.85

-4.19

P40450

PKLFPRLS

6.53

-5.50

-4.84

SPKLFPRL

6.70

-6.09

-5.43

PPPLPDLF

6.98

-6.01

-5.35

P40453

KPPDLPIR

7.21

-5.74

-5.08

PPDLPIRL

8.02

-6.14

-5.48

VPEPPSWK

8.36

-6.43

-5.77

P38822

PEVPPPRR

8.67

-5.11

-4.45

APEVPPPR

9.34

-5.78

-5.12

P41832

IPPAPPMM

7.51

-7.05

-6.39

PPPPMALF

8.96

-4.01

-3.35

APPMMPAS

9.05

-5.21

-4.55

P53094

KLPPLPLT

7.32

-5.14

-4.48

PLKLPPLP

8.00

-6.70

-6.04

LPPLPLTS

8.33

-6.16

-5.50

Q04439

SKPKEPMF

7.18

-5.83

-5.17

KPKEPMFE

7.88

-6.61

-5.95

APPPPGMQ

9.26

-6.16

-5.50

P37370

RPHMPSVR

4.93

-7.49

-6.83

MPKPRPFQ

6.17

-6.83

-6.17

APPLPTFS

6.84

-7.13

-6.47

P40021

PPLPPPLF

8.27

-5.31

-4.65

HPPNHPHS

8.84

-5.63

-4.97

YVISPNLP

8.95

-5.04

-4.38

P40341

PPPKPPLN

6.36

-6.71

-6.05

SRNIPPPP

9.95

-6.07

-5.41

KPPLNDPS

10.15

-4.47

-3.81

Q01560

PEPQPYYP

9.31

-3.35

-2.69

QPYYPPPP

9.82

-6.48

-5.82

YPPPPPGE

9.89

-6.10

-5.44

P17555

RPKKPSTL

7.53

-5.41

-4.75

PPPRPKKP

9.27

-6.59

-5.93

PRPKKPST

10.15

-3.87

-3.21

P00950

DVPPPPID

11.19

-4.05

-3.39

P33334

GPKFEPLY

7.02

-4.79

-4.13

MPTRFPPA

8.00

-6.62

-5.96

IPGGPKFE

8.77

-6.14

-5.48

P25604

KPKSPHLK

7.96

-4.83

-4.17

LPPKPNTQ

8.19

-5.91

-5.25

KPPLPPPP

9.56

-7.65

-6.99

 


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