ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-11.PDB
Scoring matrix: MYO3_1YP5-11_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.83
Foldx random average score for Saccharomyces cerevisiae: 9.817

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3220633
Proteins after random average filtering: 7178
 Total fragments: 1192766
Proteins after disorder filtering: 4566
 Total fragments: 73750
Proteins after pattern filtering: 2257
 Total fragments: 12498
Proteins after MINT filtering: 25
 Total fragments: 744


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.83

-0.50

0.00

Best peptides

YMPIPPR

0.00

-6.49

-6.00

         
Interactors      
P39113

RGPRRPQ

6.10

-5.19

-4.70

APPPPPH

6.40

-5.28

-4.79

GPRRPQK

6.77

-4.98

-4.49

P25604

KPPLPPP

6.69

-7.37

-6.88

LPPPPPP

6.88

-6.13

-5.63

LPPKPKS

6.99

-6.23

-5.74

P38822

PEVPPPR

6.65

-3.92

-3.42

APEVPPP

6.83

-5.54

-5.04

P40341

PPPKPPL

6.04

-6.69

-6.20

IPPPPPP

6.40

-5.02

-4.52

RNIPPPP

6.87

-6.74

-6.25

Q08912

PPPPPPP

7.19

-6.07

-5.58

YTPSWGP

7.75

-3.06

-2.56

GPPPPPP

7.97

-5.00

-4.50

P17555

RPKKPST

5.24

-7.64

-7.14

PPPRPKK

5.91

-6.34

-5.84

APPPPPP

7.06

-5.48

-4.99

Q12342

APPPPPP

7.06

-5.48

-4.99

PPPPPPP

7.19

-6.07

-5.58

AKAPPPP

7.90

-4.23

-3.74

P47068

APSIPPV

6.49

-4.93

-4.43

APSPPPH

6.82

-4.48

-3.99

IPPVPPT

6.82

-5.07

-4.58

P04050

VPPPPVR

5.29

-3.98

-3.48

SPAYSPK

6.96

-3.03

-2.53

APTSPGF

7.27

-4.09

-3.59

P40450

SPKLFPR

6.13

-5.02

-4.52

LPPPPPP

6.88

-6.13

-5.63

VPPPPPP

7.07

-4.66

-4.17

P40453

RPPPPPP

4.92

-8.26

-7.76

TPEIPPP

5.59

-4.39

-3.89

RKRPPPP

5.62

-7.57

-7.08

P41832

IPPAPPM

6.73

-5.12

-4.63

APPMMPA

6.81

-4.94

-4.45

PPPVPAK

6.91

-5.80

-5.30

P38237

DPFVPPP

6.17

-5.03

-4.54

PPNVPKK

7.49

-5.74

-5.25

IPSKPEN

7.83

-5.00

-4.50

P53094

YPLKLPP

4.47

-7.46

-6.96

FPQSPIR

6.56

-3.84

-3.34

EPPPPCP

7.40

-4.78

-4.29

Q01389

YPQTPSY

4.08

-6.45

-5.96

EPSTPSR

5.15

-5.80

-5.30

PPPIPKT

6.56

-5.03

-4.54

P40021

PLPPPAR

6.23

-4.90

-4.41

HPPNHPH

6.37

-3.99

-3.50

LPSTPSQ

7.06

-5.66

-5.17

Q04439

KPKEPMF

6.06

-5.49

-5.00

IPPPPPP

6.40

-5.02

-4.52

RPSPPTA

6.81

-6.35

-5.85

Q12446

APPPPPR

4.66

-5.64

-5.14

PPPPPRR

5.07

-5.69

-5.20

PPPPPHR

5.20

-6.14

-5.64

Q01560

YPPPPPG

5.15

-7.42

-6.92

YYPPPPP

5.47

-6.12

-5.63

QPYYPPP

5.90

-5.84

-5.34

P00950

VPPPPID

8.94

-3.51

-3.01

DVPPPPI

9.03

-3.95

-3.46

FDVPPPP

9.16

-3.72

-3.23

P33334

MPTRFPP

5.74

-5.60

-5.10

PPPPPGY

6.19

-5.33

-4.84

PPPPPGF

6.35

-5.81

-5.31

P40523

APPPHGP

7.47

-4.30

-3.80

PPPHGPF

7.53

-4.26

-3.76

PLAPPPH

7.83

-5.00

-4.50

Q08989

PPPPPPP

7.19

-6.07

-5.58

GPPPPPP

7.97

-5.00

-4.50

PKGPPPP

8.21

-4.40

-3.91

P37370

RPHMPSV

4.77

-6.38

-5.88

APPIPGM

5.22

-5.52

-5.02

IPDIPSS

5.77

-4.33

-3.84

P39743

NPLTSPV

9.38

-2.06

-1.56

 


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