ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1VA7-4.PDB
Scoring matrix: MYO3_1VA7-4_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.08
Foldx random average score for Saccharomyces cerevisiae: 23.341

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199099
Proteins after random average filtering: 7178
 Total fragments: 1649642
Proteins after disorder filtering: 4517
 Total fragments: 100733
Proteins after pattern filtering: 2265
 Total fragments: 20052
Proteins after MINT filtering: 25
 Total fragments: 1002


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.08

1.75

0.00

Best peptides

FRPRRFMPPF

0.00

-6.47

-8.22

         
Interactors      
P39113

HRGPRRPQKN

10.28

-5.64

-7.39

PLGAPPPPPH

13.00

-6.33

-8.08

GPRRPQKNRY

14.58

-2.37

-4.12

P36150

PIVVNPSSPS

16.91

-4.17

-5.92

NPIVVNPSSP

22.55

-1.59

-3.34

P38822

DRGPAPEVPP

15.99

-3.59

-5.34

PAPEVPPPRR

16.78

-5.16

-6.91

APEVPPPRRS

17.10

-3.79

-5.54

P40341

PPPPPPPPPK

12.51

-6.54

-8.29

PPPPPPKPPL

13.00

-5.66

-7.41

SRNIPPPPPP

14.27

-4.03

-5.78

Q08912

PKGPPPPPPP

12.89

-5.50

-7.25

PPPPPPPDEK

14.89

-5.09

-6.84

KGPPPPPPPD

15.36

-3.33

-5.08

P17555

SKSGPPPRPK

10.02

-4.84

-6.59

PRPKKPSTLK

12.48

-3.79

-5.54

APAPPPPPPA

14.30

-5.59

-7.34

P25604

LKPPLPPPPP

11.80

-5.16

-6.91

PLPPKPKSPH

12.35

-4.88

-6.63

PKSPHLKPPL

13.52

-2.16

-3.91

P47068

DKVPPHPVPS

12.48

-3.86

-5.61

MPNTAPPLPR

15.03

-6.57

-8.32

PLPRAPPVPP

15.09

-6.02

-7.77

P04050

PVPPPPVRPS

15.97

-3.76

-5.51

TCLPVPPPPV

16.48

-3.46

-5.21

SPGYSPGSPA

16.51

-2.94

-4.69

P40450

PPPPPPPPPL

12.86

-6.43

-8.18

PPPPPPPLPQ

14.42

-6.49

-8.24

PPPPPPPLPE

14.74

-6.41

-8.16

P40453

LRKRPPPPPP

9.01

-8.88

-10.63

RKRPPPPPPV

10.32

-4.65

-6.40

KRPPPPPPVS

13.09

-3.34

-5.09

P41832

PPPPPPPPPM

12.44

-6.45

-8.20

PKGETPPPPP

13.63

-5.04

-6.79

PPPPPPPPPV

14.25

-6.19

-7.94

Q12342

AKAPPPPPPP

12.67

-5.25

-7.00

RKAKAPPPPP

13.02

-4.80

-6.55

APPPPPPPPP

16.70

-6.01

-7.76

P38237

FVPPPNVPKK

16.46

-2.91

-4.66

PFVPPPNVPK

18.72

-2.78

-4.53

DLNDPFVPPP

18.77

-4.97

-6.72

P53094

YPLKLPPLPL

13.08

-6.36

-8.11

FKSSAFPQSP

13.93

-3.88

-5.63

TREPNEPPPP

14.96

-4.39

-6.14

Q01389

PKREAPKPPA

10.74

-4.18

-5.93

KREAPKPPAN

11.91

-4.60

-6.35

KRSKPLPPQL

14.30

-4.04

-5.79

P40021

TKNTGPPPPL

11.15

-4.03

-5.78

PPPPLPPPLF

15.25

-5.02

-6.77

NSPPLPPPAR

15.66

-3.00

-4.75

Q04439

KKPAPPPPGM

8.52

-4.51

-6.26

PKEPMFEAAY

10.73

-2.72

-4.47

SKKPAPPPPG

11.69

-3.98

-5.73

Q12446

NRPVPPPPPM

7.20

-5.93

-7.68

HKAPPPPPPT

8.41

-5.15

-6.90

PKHSLPPLPN

10.56

-5.20

-6.95

Q01560

QPYYPPPPPG

12.36

-5.66

-7.41

PQPYYPPPPP

15.29

-4.91

-6.66

YYPPPPPGEH

15.80

-3.20

-4.95

P00950

RSFDVPPPPI

16.12

-3.42

-5.17

DVPPPPIDAS

17.30

-0.76

-2.51

FDVPPPPIDA

19.47

-1.55

-3.30

P33334

SKMPTRFPPA

12.25

-2.16

-3.91

FLPPPPPPPS

12.29

-6.58

-8.33

KMPTRFPPAV

12.94

-4.29

-6.04

P40523

GVPPLAPPPH

14.93

-3.90

-5.65

YMHNSPRNPD

16.88

-4.38

-6.13

PLAPPPHGPF

17.17

-4.39

-6.14

Q08989

PKGPPPPPPP

12.89

-5.50

-7.25

PPPPPPPDEK

14.89

-5.09

-6.84

GPPPPPPPPD

15.06

-5.52

-7.27

P37370

PKPRPFQNKT

9.68

-2.32

-4.07

EKPPSPPVAA

12.36

-2.94

-4.69

LPPSAPPPPI

13.22

-7.02

-8.77

 


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