ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1VA7-21.PDB
Scoring matrix: MYO3_1VA7-21_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.64
Foldx random average score for Saccharomyces cerevisiae: 15.886

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199099
Proteins after random average filtering: 7178
 Total fragments: 1788978
Proteins after disorder filtering: 4432
 Total fragments: 68586
Proteins after pattern filtering: 1584
 Total fragments: 3596
Proteins after MINT filtering: 22
 Total fragments: 122


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.64

-0.54

0.00

Best peptides

EERMGMPMMK

0.00

-5.31

-4.77

         
Interactors      
P39113

HRGPRRPQKN

10.92

-2.97

-2.43

PRRPQKNRYN

11.30

-2.50

-1.96

PEGPNCTNTN

12.52

-3.28

-2.74

P25604

PPKPKSPHLK

9.75

-4.55

-4.01

PPQPASNALD

13.92

-4.07

-3.53

PPKPNTQLQQ

15.36

-3.14

-2.60

Q08989

PPPPDEKGRG

14.76

-3.58

-3.04

P40341

LNDPSNPVSK

11.51

-2.75

-2.21

P17555

PKKPSTLKTK

10.89

-3.23

-2.69

PPRPKKPSTL

12.81

-1.94

-1.40

PRPKKPSTLK

13.03

-3.80

-3.26

Q08912

PPPPDEKDRG

15.58

-2.79

-2.25

Q12342

LETPSTPSDG

13.64

-2.46

-1.92

PSTPSDGGSS

15.54

-1.25

-0.71

P47068

PEPISPETKK

10.00

-5.07

-4.53

LPEPISPETK

11.51

-2.38

-1.84

DPSSNPFFRK

13.83

-2.19

-1.65

P04050

GEAPTSPGFG

11.75

-2.76

-2.22

GYSPGSPAYS

11.80

-2.78

-2.24

TYSPTSPAYS

13.16

-2.45

-1.91

P40450

PPLPDLFKTK

10.14

-3.25

-2.71

PPLPESLSMN

12.74

-4.36

-3.82

SSPKLFPRLS

13.13

-3.48

-2.94

P40453

PDLPIRLRKR

10.86

-3.33

-2.79

TKVPEPPSWK

13.80

-3.74

-3.20

WKPPDLPIRL

14.08

-2.88

-2.34

P41832

PPPPMALFGK

15.25

-2.71

-2.17

PPLPSVLSSS

15.79

-2.14

-1.60

P38237

FQIPSKPENT

12.79

-0.81

-0.27

VPPPNVPKKD

13.29

-3.88

-3.34

PSKPENTVNL

13.43

-2.03

-1.49

Q01389

RRYPQTPSYY

11.99

-2.34

-1.80

REAPKPPANT

12.00

-3.01

-2.47

RSKPLPPQLL

13.00

-3.08

-2.54

P40021

DFLPSTPSQM

13.43

-3.60

-3.06

PSTPSQMNYD

13.97

-2.28

-1.74

SHPPNHPHSQ

15.07

-1.85

-1.31

Q04439

SSKPKEPMFE

10.94

-3.77

-3.23

NNIPTPPQNR

12.02

-2.44

-1.90

PPPPGMQNKA

13.92

-3.98

-3.44

Q12446

RPLPQLPNRN

11.27

-3.25

-2.71

PEIPSTQSAT

12.46

-2.59

-2.05

LPPASPEVRK

13.08

-2.76

-2.22

Q01560

PQEPQVPQES

12.56

-0.61

-0.07

PPPPGEHMHG

14.35

-3.64

-3.10

PPAPQEQNDV

15.50

-1.90

-1.36

P33334

NAIPGGPKFE

10.90

-3.77

-3.23

MPTRFPPAVF

14.90

-2.58

-2.04

P40523

PHGPFSTSML

12.29

-3.10

-2.56

HNSPRNPDTG

14.45

-1.40

-0.86

APPGTVPNMQ

14.60

-3.30

-2.76

P53094

LNVPLPPQTR

12.23

-3.41

-2.87

SAFPQSPIRA

12.79

-3.29

-2.75

AFPQSPIRAY

15.28

-1.92

-1.38

P37370

QNRPHMPSVR

9.56

-3.27

-2.73

ASAPKVPQNR

10.24

-1.91

-1.37

MPKPRPFQNK

11.18

-2.17

-1.63

 


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