ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1VA7-12.PDB
Scoring matrix: MYO3_1VA7-12_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.82
Foldx random average score for Saccharomyces cerevisiae: 13.319

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213455
Proteins after random average filtering: 7178
 Total fragments: 1159592
Proteins after disorder filtering: 4423
 Total fragments: 56474
Proteins after pattern filtering: 2128
 Total fragments: 11004
Proteins after MINT filtering: 26
 Total fragments: 666


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.82

-1.09

0.00

Best peptides

RKIPRRWR

0.00

-4.17

-3.08

         
Interactors      
P39113

SHRGPRRP

7.25

-3.28

-2.19

HRGPRRPQ

8.31

-1.96

-0.87

PRRPQKNR

11.29

-3.02

-1.93

P36150

IVVNPSSP

13.15

-2.17

-1.08

P38822

PEVPPPRR

10.30

-3.84

-2.75

RGPAPEVP

12.97

-1.34

-0.25

P40341

RNIPPPPP

9.22

-3.28

-2.19

NIPPPPPP

11.18

-3.52

-2.43

PPPPPKPP

11.73

-4.40

-3.31

Q08912

KGPPPPPP

10.93

-3.45

-2.36

CYTPSWGP

11.40

-2.95

-1.86

GPPPPPPP

12.28

-3.46

-2.37

P17555

SGPPPRPK

6.20

-3.62

-2.53

PKKPSTLK

11.43

-2.29

-1.20

PAPPPPPP

11.50

-3.77

-2.68

P25604

HLKPPLPP

10.17

-3.65

-2.56

LKPPLPPP

10.66

-3.43

-2.34

PKPKSPHL

10.82

-2.65

-1.56

P47068

APPLPRAP

8.24

-3.14

-2.05

DKVPPHPV

10.22

-3.95

-2.86

YVPPGIPT

10.31

-2.29

-1.20

P04050

PPPPVRPS

7.77

-3.27

-2.18

PVRPSISF

11.10

-2.56

-1.47

VSSPGFSP

11.32

-3.09

-2.00

P40450

PKLFPRLS

8.44

-3.18

-2.09

SSPKLFPR

8.78

-4.12

-3.03

PAPPPLPD

10.65

-4.01

-2.92

P40453

PDLPIRLR

8.73

-3.19

-2.10

PEPPSWKP

8.84

-4.70

-3.61

RKRPPPPP

9.15

-3.67

-2.58

P41832

PAPPMMPA

9.76

-4.44

-3.35

PPPPPMAL

10.08

-4.72

-3.63

PPAPPMMP

10.73

-4.56

-3.47

Q12342

KAPPPPPP

10.92

-3.49

-2.40

KAKAPPPP

11.53

-3.04

-1.95

AKAPPPPP

11.79

-2.65

-1.56

P38237

FQIPSKPE

9.61

-3.17

-2.08

PFVPPPNV

11.61

-4.06

-2.97

FVPPPNVP

12.58

-2.36

-1.27

P53094

PQSPIRAY

9.32

-1.88

-0.79

KLPPLPLT

11.22

-2.74

-1.65

LKLPPLPL

11.45

-4.47

-3.38

Q01389

PSTPSRPV

8.28

-2.58

-1.49

RSKPLPPQ

10.44

-3.19

-2.10

SSPPPIPK

10.67

-2.36

-1.27

P40021

LPPPLFPS

9.73

-4.56

-3.47

PLPPPLFP

10.99

-5.02

-3.93

YVISPNLP

11.25

-2.54

-1.45

Q04439

ANIPPPPP

10.25

-3.34

-2.25

PKEPMFEA

10.39

-3.34

-2.25

KKPAPPPP

10.48

-3.03

-1.94

Q12446

PPPPPRRG

6.49

-4.22

-3.13

PPPPHRHV

6.85

-4.01

-2.92

PPPPRRGP

7.13

-3.83

-2.74

Q01560

YYPPPPPG

10.65

-3.68

-2.59

PYYPPPPP

11.57

-3.88

-2.79

YPPPPPGE

11.71

-2.97

-1.88

P00950

FDVPPPPI

11.25

-3.55

-2.46

DVPPPPID

11.27

-3.15

-2.06

VPPPPIDA

12.41

-2.95

-1.86

P33334

SKMPTRFP

5.76

-4.58

-3.49

KMPTRFPP

9.80

-3.91

-2.82

PPPPGFEE

10.37

-5.05

-3.96

P40523

MHNSPRNP

9.67

-2.53

-1.44

VGVPPLAP

10.47

-4.42

-3.33

LAPPPHGP

11.55

-2.68

-1.59

Q08989

KGPPPPPP

10.93

-3.45

-2.36

PPPPPPPP

12.24

-3.75

-2.66

GPPPPPPP

12.28

-3.46

-2.37

P37370

QMPKPRPF

6.67

-3.47

-2.38

KVPQNRPH

7.45

-2.63

-1.54

HMPSVRPA

8.01

-3.04

-1.95

P39743

ATIPEDNP

11.92

-1.99

-0.90

 


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