ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1RUW-23.PDB
Scoring matrix: MYO3_1RUW-23_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.86
Foldx random average score for Saccharomyces cerevisiae: 10.369

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3220633
Proteins after random average filtering: 7178
 Total fragments: 1487917
Proteins after disorder filtering: 4618
 Total fragments: 64311
Proteins after pattern filtering: 1953
 Total fragments: 8106
Proteins after MINT filtering: 25
 Total fragments: 412


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.86

-0.84

0.00

Best peptides

RPLYPWH

0.00

-4.10

-3.26

         
Interactors      
P39113

RGPRRPQ

7.80

-3.45

-2.61

APPPPPH

7.93

-1.74

-0.90

PPPPPHK

8.43

-2.62

-1.78

P25604

PHLKPPL

7.20

-3.45

-2.61

TPPLPPK

7.27

-3.34

-2.50

PPLPPKP

7.87

-3.58

-2.74

P38822

PEVPPPR

8.70

-3.33

-2.49

P40341

PPPPPPK

8.11

-2.22

-1.38

RNIPPPP

8.15

-3.74

-2.90

PSNPVSK

8.83

-2.44

-1.60

Q08912

PPPPPDE

8.42

-1.82

-0.98

PPPPDEK

8.45

-3.04

-2.20

PPPPPPD

9.45

-2.37

-1.53

P17555

PPPRPKK

7.40

-3.37

-2.53

RPKKPST

8.47

-3.37

-2.53

GPPPRPK

9.27

-1.45

-0.61

Q12342

PSTPSDG

10.13

-2.03

-1.19

P47068

APSPPPH

8.22

-1.08

-0.24

APPLPRA

8.67

-2.41

-1.57

PGIPTND

8.68

-2.77

-1.93

P04050

SPAYSPK

7.92

-1.29

-0.45

SPNYSPT

8.46

-1.87

-1.03

SPTYSPT

9.20

-1.09

-0.25

P40450

PKLFPRL

4.44

-4.02

-3.18

PPLPDLF

6.90

-3.38

-2.54

PPLPESL

6.96

-3.59

-2.75

P40453

PPLPPKI

5.73

-3.53

-2.69

PDLPIRL

6.24

-3.88

-3.04

PEIPPPL

7.10

-2.36

-1.52

P41832

PPLPSVL

7.62

-2.87

-2.03

PPAPPMM

7.92

-2.38

-1.54

PPMMPAS

7.97

-5.12

-4.28

P38237

PPNVPKK

7.00

-2.75

-1.91

IPSKPEN

9.53

-2.06

-1.22

PPPNVPK

9.75

-2.98

-2.14

P53094

VPLPPQT

7.58

-3.52

-2.68

LKLPPLP

8.29

-4.00

-3.16

LPPLPLT

8.36

-3.35

-2.51

Q01389

KPLPPQL

5.56

-4.66

-3.82

RPVPPDS

7.45

-2.42

-1.58

SPSYPSI

8.20

-1.81

-0.97

P40021

PPLFPSS

6.31

-3.67

-2.83

PPLPPPL

6.41

-3.77

-2.93

PPLPPPA

7.27

-3.73

-2.89

Q04439

PPPPGMQ

7.96

-2.75

-1.91

KPKEPMF

8.02

-3.27

-2.43

PPPPSSK

8.89

-2.64

-1.80

Q12446

LPQLPNR

6.34

-4.93

-4.09

PPPPHRH

6.92

-1.94

-1.10

PPPPPMR

7.14

-3.02

-2.18

Q01560

PPPPGEH

7.69

-2.92

-2.08

EPQVPQE

8.80

-1.69

-0.85

QEPPAPQ

8.86

-2.20

-1.36

P00950

PPPPIDA

9.12

-1.35

-0.51

VPPPPID

9.65

-1.58

-0.74

P33334

GPKFEPL

8.28

-2.51

-1.67

PTRFPPA

8.67

-3.71

-2.87

LALPPPP

8.80

-2.82

-1.98

P40523

TPLPTPV

7.67

-2.45

-1.61

PLAPPPH

8.27

-1.74

-0.90

TPQPPSA

8.80

-1.69

-0.85

Q08989

PPPPPDE

8.42

-1.82

-0.98

PPPPDEK

8.45

-3.04

-2.20

PPPPPPD

9.45

-2.37

-1.53

P37370

PPIPTSH

6.32

-2.59

-1.75

PPLPAAM

7.13

-3.64

-2.80

PPLPTFS

7.37

-3.53

-2.69

P39743

NPLTSPV

9.97

-1.87

-1.03

 


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