ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1RUW-18.PDB
Scoring matrix: MYO3_1RUW-18_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 17.63
Foldx random average score for Saccharomyces cerevisiae: 16.322

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199099
Proteins after random average filtering: 7178
 Total fragments: 1544412
Proteins after disorder filtering: 4513
 Total fragments: 78110
Proteins after pattern filtering: 2136
 Total fragments: 10261
Proteins after MINT filtering: 26
 Total fragments: 329


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

17.63

-0.14

0.00

Best peptides

RMPLHGVRWR

0.00

-4.02

-3.88

         
Interactors      
P39113

RGPRRPQKNR

11.06

-2.82

-2.68

PRRPQKNRYN

12.42

-3.01

-2.87

ASHRGPRRPQ

12.68

-1.14

-1.00

P36150

PIVVNPSSPS

15.67

-2.65

-2.51

P38822

VGDTPTTTPG

15.04

-1.48

-1.34

RGPAPEVPPP

15.17

-1.01

-0.87

APEVPPPRRS

15.66

-2.65

-2.51

P40341

SRNIPPPPPP

14.66

-3.26

-3.12

RNIPPPPPPP

15.60

-1.49

-1.35

Q08912

YTPSWGPSPM

13.30

-1.58

-1.44

VCYTPSWGPS

14.58

-1.47

-1.33

THGDHPKGPP

14.61

0.26

0.40

P17555

SKSGPPPRPK

12.73

-1.07

-0.93

RPKKPSTLKT

14.14

-3.51

-3.37

KSGPPPRPKK

16.05

-1.88

-1.74

P25604

PKPKSPHLKP

13.43

0.17

0.31

EQNTPPLPPK

13.87

-1.62

-1.48

QAPSLPPKPN

14.20

-1.47

-1.33

P47068

VDPSSNPFFR

11.86

-1.77

-1.63

SRTLPPHVPS

11.97

-3.37

-3.23

YHPMPNTAPP

12.01

-3.55

-3.41

P04050

PVPPPPVRPS

13.83

-2.10

-1.96

CLPVPPPPVR

14.16

-1.65

-1.51

FSPTSPTYSP

14.24

1.05

1.19

P40450

VSSSPKLFPR

12.84

0.10

0.24

KLPQLPPPPP

14.47

-3.89

-3.75

VSCIAAPAPP

15.00

-1.82

-1.68

P40453

RLRKRPPPPP

12.65

-4.29

-4.15

WKPPDLPIRL

12.80

-1.65

-1.51

PDLPIRLRKR

13.11

-1.15

-1.01

P41832

KGETPPPPPL

14.71

-3.00

-2.86

DGVIPPAPPM

14.97

-3.05

-2.91

LSSQPPPPPP

15.52

-3.06

-2.92

Q12342

RKAKAPPPPP

12.59

-3.09

-2.95

P38237

PFVPPPNVPK

14.19

-1.78

-1.64

FVPPPNVPKK

14.48

-3.06

-2.92

DLNDPFVPPP

14.67

-1.94

-1.80

P53094

AFPQSPIRAY

11.39

-2.09

-1.95

REPNEPPPPC

13.23

-3.37

-3.23

NVPLPPQTRE

13.45

-3.25

-3.11

Q01389

RYPQTPSYYY

9.43

-2.92

-2.78

RRYPQTPSYY

12.19

-2.61

-2.47

ASPSYPSIFR

12.93

-1.94

-1.80

P40021

NYVISPNLPT

11.52

-2.20

-2.06

FLPSTPSQMN

12.66

-3.12

-2.98

LDFLPSTPSQ

13.80

-3.05

-2.91

Q04439

RHSKKPAPPP

14.07

-1.73

-1.59

PSSKPKEPMF

14.21

-2.00

-1.86

RQANIPPPPP

14.23

-2.28

-2.14

Q12446

NRPLPQLPNR

11.21

-3.66

-3.52

RLPAPPPPPR

11.30

-3.31

-3.17

SAPIPPTLPS

12.06

-2.57

-2.43

Q01560

HHQPPEPQPY

14.79

-0.99

-0.85

HQPPEPQPYY

14.89

-1.88

-1.74

QAPDAPQEPQ

14.96

-1.74

-1.60

P00950

RSFDVPPPPI

13.76

-2.05

-1.91

RRSFDVPPPP

14.82

-1.79

-1.65

P33334

LFFDPSLNPI

11.49

-2.64

-2.50

NNAIPGGPKF

12.01

0.43

0.57

NAIPGGPKFE

12.61

-1.62

-1.48

P40523

GGPLASPTHY

12.91

-3.61

-3.47

YMHNSPRNPD

13.26

-3.31

-3.17

LGAPPGTVPN

13.60

-1.39

-1.25

Q08989

TNGDHPKGPP

14.90

-1.33

-1.19

DHPKGPPPPP

16.28

-0.73

-0.59

P37370

VSQMPKPRPF

10.87

-3.08

-2.94

RPHMPSVRPA

11.91

-3.14

-3.00

QMPKPRPFQN

12.81

-2.26

-2.12

P39743

AYSNPLTSPV

13.53

-1.82

-1.68

 


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