ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1R6S-23.PDB
Scoring matrix: MYO3_1R6S-23_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.56
Foldx random average score for Saccharomyces cerevisiae: 8.848

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3220633
Proteins after random average filtering: 7178
 Total fragments: 1487532
Proteins after disorder filtering: 4558
 Total fragments: 55688
Proteins after pattern filtering: 1859
 Total fragments: 6171
Proteins after MINT filtering: 20
 Total fragments: 208


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.56

-0.55

0.00

Best peptides

YRLMPWH

0.00

-4.43

-3.88

         
Interactors      
Q12446

LPQLPNR

5.99

-4.03

-3.48

LPPLPNQ

6.00

-3.71

-3.16

PFPIPEI

6.54

-2.91

-2.36

P47068

LPPHVPS

7.35

-2.40

-1.85

PEPISPE

7.61

-3.22

-2.67

PPHVPSL

7.74

-2.62

-2.07

P39113

RGPRRPQ

6.56

-3.31

-2.76

GPRRPQK

6.89

-2.96

-2.41

MSPLGAP

7.58

-3.76

-3.21

Q01389

PPPIPKT

6.73

-3.85

-3.30

SKPLPPQ

7.50

-3.24

-2.69

SPSYPSI

7.83

-0.72

-0.17

P04050

SPAYSPK

7.24

-1.38

-0.83

PPVRPSI

8.01

-3.22

-2.67

CLPVPPP

8.07

-2.51

-1.96

P40523

PPLAPPP

7.33

-4.44

-3.89

PPPHGPF

7.74

-2.70

-2.15

PGTVPNM

7.92

-2.35

-1.80

P38237

PPNVPKK

6.53

-4.12

-3.57

IPSKPEN

7.49

-2.18

-1.63

PPPNVPK

7.74

-3.74

-3.19

P40450

PKLFPRL

6.37

-5.95

-5.40

LPQLPPP

6.82

-3.91

-3.36

PPPLPDL

7.01

-3.82

-3.27

P40453

PPPLPPK

6.10

-4.78

-4.23

PPDLPIR

6.62

-3.84

-3.29

TPEIPPP

6.84

-1.43

-0.88

P38822

APEVPPP

8.53

-0.48

0.07

P41832

PPMMPAS

6.74

-4.88

-4.33

PPPVPAK

6.96

-4.30

-3.75

PPPLPSV

7.87

-3.94

-3.39

P53094

YPLKLPP

4.75

-4.70

-4.15

PLKLPPL

6.67

-4.17

-3.62

LPPLPLT

6.73

-3.78

-3.23

Q04439

KPKEPMF

7.02

-2.96

-2.41

SKPKEPM

7.47

-1.86

-1.31

PSSKPKE

7.63

-2.20

-1.65

P37370

PSINPPK

6.15

-4.25

-3.70

RPHMPSV

6.30

-3.45

-2.90

PKPRPFQ

6.54

-3.47

-2.92

P40021

PPNHPHS

7.06

-2.87

-2.32

PPPLPPP

7.13

-4.62

-4.07

HPPNHPH

7.26

-2.23

-1.68

P40341

PPPKPPL

6.87

-3.37

-2.82

KPPLNDP

7.74

-4.46

-3.91

PPLNDPS

8.14

-4.00

-3.45

Q01560

QPYYPPP

6.70

-1.35

-0.80

PQPYYPP

7.75

-2.59

-2.04

QEPQVPQ

8.11

-1.54

-0.99

P17555

PPPRPKK

5.77

-4.30

-3.75

RPKKPST

6.63

-2.75

-2.20

PRPKKPS

8.35

-2.66

-2.11

P33334

PSLNPIP

6.77

-3.98

-3.43

MPTRFPP

7.80

-4.17

-3.62

NPMVPSS

8.14

-3.37

-2.82

P25604

PHLKPPL

5.57

-3.74

-3.19

TPPLPPK

5.99

-3.34

-2.79

PKPKSPH

6.25

-2.85

-2.30

 


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