ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1R6S-13.PDB
Scoring matrix: MYO3_1R6S-13_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.34
Foldx random average score for Saccharomyces cerevisiae: 12.211

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213455
Proteins after random average filtering: 7178
 Total fragments: 1292535
Proteins after disorder filtering: 4374
 Total fragments: 49047
Proteins after pattern filtering: 1787
 Total fragments: 6464
Proteins after MINT filtering: 21
 Total fragments: 217


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.34

-1.14

0.00

Best peptides

WWPRFPWH

0.00

-4.41

-3.27

         
Interactors      
Q12446

RNNRPVPP

9.57

-5.17

-4.03

KHSLPPLP

9.63

-5.88

-4.74

RLPAPPPP

9.69

-6.18

-5.04

P47068

PSSNPFFR

10.39

-4.26

-3.12

YYVPPGIP

10.43

-6.25

-5.11

TAPPLPRA

11.06

-4.90

-3.76

P39113

RGPRRPQK

7.86

-4.90

-3.76

GPRRPQKN

10.49

-4.20

-3.06

LFTHPEGP

11.48

-3.93

-2.79

Q01389

YPQTPSYY

9.75

-3.40

-2.26

RYPQTPSY

9.84

-4.31

-3.17

SKPLPPQL

10.09

-5.90

-4.76

P04050

PPVRPSIS

10.84

-4.11

-2.97

CLPVPPPP

11.84

-5.52

-4.38

SPTSPSYS

12.07

-2.63

-1.49

P40523

PLASPTHY

10.54

-4.79

-3.65

PLAPPPHG

10.89

-6.06

-4.92

PGTVPNMQ

11.00

-4.24

-3.10

P38237

NFQIPSKP

10.31

-5.44

-4.30

IPSKPENT

11.81

-2.28

-1.14

TFPEPEVP

12.15

-4.53

-3.39

P40450

PKLFPRLS

7.52

-6.39

-5.25

KLPQLPPP

10.31

-5.31

-4.17

SPKLFPRL

10.86

-4.18

-3.04

P40453

LRKRPPPP

9.21

-5.97

-4.83

RKRPPPPP

9.25

-6.41

-5.27

SWKPPDLP

10.38

-4.00

-2.86

P38822

PEVPPPRR

9.99

-5.09

-3.95

RGPAPEVP

10.90

-5.09

-3.95

P41832

IPPAPPMM

10.48

-4.83

-3.69

KGETPPPP

11.43

-4.17

-3.03

LSSQPPPP

11.72

-4.64

-3.50

P53094

KLPPLPLT

7.72

-6.09

-4.95

PLKLPPLP

9.46

-6.88

-5.74

AFPQSPIR

10.36

-3.80

-2.66

Q04439

SKPKEPMF

8.83

-5.68

-4.54

NIPTPPQN

10.38

-5.35

-4.21

KPKEPMFE

10.86

-3.67

-2.53

P37370

PKPRPFQN

8.29

-5.12

-3.98

RPHMPSVR

8.73

-5.84

-4.70

MPKPRPFQ

9.10

-4.29

-3.15

P40021

PLPPPARS

9.44

-4.99

-3.85

PLPPPLFP

9.75

-5.52

-4.38

HPPNHPHS

9.79

-5.09

-3.95

P40341

PPPKPPLN

10.35

-4.92

-3.78

RNIPPPPP

11.23

-5.31

-4.17

Q01560

PEPQPYYP

10.57

-4.14

-3.00

YYPPPPPG

10.73

-6.44

-5.30

HHQPPEPQ

11.37

-4.09

-2.95

Q08912

HGDHPKGP

11.77

-3.74

-2.60

YTPSWGPS

11.81

-1.80

-0.66

P17555

KSGPPPRP

10.77

-4.77

-3.63

RPKKPSTL

11.38

-4.61

-3.47

PPPRPKKP

11.47

-3.49

-2.35

P33334

MPTRFPPA

9.91

-4.19

-3.05

SKMPTRFP

11.17

-3.29

-2.15

FLPPPPPP

11.25

-5.64

-4.50

P25604

PLPPKPKS

10.21

-5.30

-4.16

HLKPPLPP

10.36

-5.59

-4.45

EQNTPPLP

10.37

-4.02

-2.88

 


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