ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-8.PDB
Scoring matrix: LSB3_2A08-8_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.33
Foldx random average score for Saccharomyces cerevisiae: 14.069

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181395
Proteins after random average filtering: 5078
 Total fragments: 1535903
Proteins after disorder filtering: 3350
 Total fragments: 125627
Proteins after pattern filtering: 1634
 Total fragments: 15306
Proteins after MINT filtering: 50
 Total fragments: 913


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.33

-1.25

0.00
Best peptides

ERRYRDPF

0.00

0.14

1.39
         
Interactors      
Q06604

PRMPSRGR

5.72

-3.24

-1.99

KNKPKPTP

7.38

-5.53

-4.28

SPPPLPTR

7.64

-7.90

-6.65
P09119

QVPLTPTT

9.86

-4.01

-2.76

TPTTSPVK

10.85

-2.90

-1.65

LTPTTSPV

12.13

-2.34

-1.09
P25604

QAPSLPPK

7.98

-5.68

-4.43

NTPPLPPK

8.16

-5.18

-3.93

LKPPLPPP

8.31

-5.21

-3.96
P40325

PRPPRPAA

5.14

-5.70

-4.45

PRPPPRPQ

5.94

-0.59

0.66

SQPPRPPR

6.13

-6.87

-5.62
Q04322

TPPTLPPR

7.44

-8.76

-7.51

APLDRPQL

7.79

-6.04

-4.79

TSPPLPPR

8.13

-7.36

-6.11
P38266

MPPPKPFR

6.42

-7.65

-6.40

QPPPKPFR

6.42

-8.29

-7.04

LPPPKPFR

6.45

-8.33

-7.08
P15891

AQPPLPSR

7.69

-6.21

-4.96

APPPPPRR

7.98

-6.92

-5.67

PPPPRRAT

8.12

-4.30

-3.05
P53169

SVPIMPTL

7.74

-5.98

-4.73

IMPTLPPR

8.21

-7.43

-6.18

PTLPPRPY

9.24

-4.38

-3.13
Q12344

SSPPLPPR

8.11

-6.32

-5.07

TSPKLPPR

8.45

-8.15

-6.90

PKLPPRGK

8.63

-4.49

-3.24
P40494

SRPPRPPP

4.45

-5.36

-4.11

PRPPPKPL

6.12

-3.44

-2.19

RPPPKPLH

7.50

-6.22

-4.97
P53238

GRPIPPAP

7.14

-4.52

-3.27

AGRPIPPA

8.62

-4.80

-3.55

QKPAGRPI

9.89

-2.02

-0.77
P32660

PNRPKVTK

6.82

-6.51

-5.26

GYDPTDPN

7.47

-1.06

0.19

PTDPNRPK

9.16

-2.72

-1.47
P38739

ASPFHDPI

8.57

2.88

4.13

GSPPNDPS

9.36

0.16

1.41

SPPNDPST

10.25

-4.67

-3.42
Q04749

FNPRKPTL

6.95

-4.85

-3.60

TNPVFNPR

7.74

-3.02

-1.77

PLPVLPRR

8.24

-7.12

-5.87
P38090

CSPNDPDL

10.31

-2.74

-1.49

VCSPNDPD

10.33

-0.63

0.62

SPNDPDLT

10.69

1.74

2.99
P47129

NRKPNPPP

5.88

-5.63

-4.38

GPPLLPPR

7.27

-8.29

-7.04

PNRKPNPP

8.51

-3.79

-2.54
P40453

KRPPPPPP

6.30

-4.41

-3.16

LRKRPPPP

6.77

-4.36

-3.11

IPPPLPPK

6.83

-8.26

-7.01
P40095

PRSPNRPT

7.31

-2.36

-1.11

RSPNRPTL

8.94

-6.13

-4.88

PPPRSPNR

9.02

-7.58

-6.33
Q12168

GPPPLPPR

6.74

-8.62

-7.37

IPPPVPNR

7.61

-7.39

-6.14

DDPYFPQF

8.05

-4.37

-3.12
P32793

HGPTHPSN

11.43

-3.35

-2.10

GPTHPSNM

13.01

-1.94

-0.69

PTHPSNMS

13.76

-0.83

0.42
P36123

ARPGNPLY

5.53

-2.63

-1.38

TTPKTPPR

8.08

-5.74

-4.49

RSQPSDPK

8.32

-1.96

-0.71
Q08412

KWQPLPPE

7.13

-6.13

-4.88

PQLPTRTK

8.20

-2.80

-1.55

VPPQLPTR

8.24

-7.85

-6.60
P32855

NAPTLPKR

8.72

-4.87

-3.62

APTLPKRK

10.46

-2.16

-0.91

SNPSSSPN

10.90

-1.52

-0.27
Q06409

PRPPFPFF

4.27

-4.97

-3.72

RKTPRPPF

6.35

-5.76

-4.51

PRKTPRPP

6.87

-1.68

-0.43
P32634

LNIPLPPQ

8.03

-5.76

-4.51

TVPTEPTR

8.46

-6.23

-4.98

LNLPIVPN

8.55

-3.96

-2.71
P53118

VENPHDLP

9.62

-0.27

0.98

NPHDLPSH

10.04

-5.02

-3.77

PHDLPSHL

13.12

-1.84

-0.59
Q12199

AAPATPPR

7.73

-4.93

-3.68

PNNPQCLH

8.18

-3.82

-2.57

CNNPNNPQ

8.51

-1.60

-0.35
P19158

SLPDTPTM

9.17

-5.53

-4.28

DPSLPDTP

10.69

-1.80

-0.55

YDPSLPDT

11.23

-3.99

-2.74
P43638

GRPIPPHP

6.92

-4.60

-3.35

KGRPIPPH

7.57

-5.29

-4.04

HIPPTDAP

8.56

-0.09

1.16
P53933

RRRPPPPP

5.63

-5.82

-4.57

RRPPPPPI

5.85

-4.16

-2.91

TRRRPPPP

6.23

-4.96

-3.71
P50101

PGSPIDKS

10.41

-1.48

-0.23

VFPGSPID

12.61

-3.28

-2.03

TVFPGSPI

12.87

-1.46

-0.21
P33400

SPQILPPL

7.79

-6.26

-5.01

QPPNAPSY

9.33

-5.76

-4.51

VQPPNAPS

9.92

-1.88

-0.63
P38238

QSPTNPPY

8.84

-3.80

-2.55

SPTNPPYK

10.45

-3.97

-2.72

VQSPTNPP

10.54

-3.88

-2.63
Q06116

HSEPVEPF

8.90

-4.37

-3.12

SEPVEPFS

9.64

-3.23

-1.98

VKPFYPVT

9.90

-3.18

-1.93
Q08229

YNPTIPPR

5.69

-4.46

-3.21

TRPLPSTP

9.80

-0.36

0.89

PVQPGGHY

10.11

-3.43

-2.18
P38930

AFPDMVPK

8.31

-3.85

-2.60

FPDMVPKH

9.40

-5.50

-4.25

PDMVPKHP

11.69

-2.15

-0.90
Q12446

PPPPRASR

6.70

-7.99

-6.74

NNRPVPPP

6.92

-5.12

-3.87

PRRGPAPP

6.98

-4.32

-3.07
P32790

LPPIKPPR

6.55

-8.25

-7.00

APAPLDPF

6.78

-3.24

-1.99

PPPAMPAR

6.94

-7.94

-6.69
P33336

DRNLPSHP

9.83

-2.37

-1.12

TCDPEDYP

10.23

-1.98

-0.73

NLPSHPSS

11.77

-4.62

-3.37
P40041

GRTLPPVP

9.07

-2.06

-0.81

IPLSPPSS

11.15

-3.61

-2.36

KIPLSPPS

11.28

-3.80

-2.55
P50942

PRPCPPIR

6.23

-4.89

-3.64

PCPPIRRK

7.10

-4.51

-3.26

VPRPCPPI

8.16

-5.49

-4.24
P47030

ANNPLDKP

7.61

-2.34

-1.09

AFPPEPSM

8.77

-3.71

-2.46

DEAFPPEP

10.24

-2.50

-1.25
P40563

APPPVPKK

7.28

-7.54

-6.29

RRAPPPVP

8.49

-3.99

-2.74

VTPKVPER

8.90

-6.45

-5.20
P40528

DIPITPSH

8.78

-4.26

-3.01

PLPYPIAQ

12.38

-3.60

-2.35

LNDIPITP

13.49

-2.32

-1.07
Q12134

THQPVPSP

9.71

-4.54

-3.29

HQPVPSPM

11.05

-4.08

-2.83

QPVPSPMN

11.73

-3.78

-2.53
P53901

AMRPIPPL

7.14

-7.05

-5.80

MRPIPPLP

7.19

-4.62

-3.37

PLPPIPTR

7.69

-8.37

-7.12
P39743

SNPLTSPV

10.05

-0.83

0.42

ATIPEDNP

10.72

0.78

2.03

NPLTSPVA

11.83

-2.93

-1.68
P31374

ISPERPSF

7.33

-5.52

-4.27

KKPGTPVF

7.57

-5.06

-3.81

PPPPLDFE

8.27

-0.15

1.10
P38870

TTPERPKR

7.65

-5.51

-4.26

PERPKRKS

7.92

-3.60

-2.35

STPTTPER

8.95

-5.48

-4.23
P53955

QRNPIPYP

6.44

-4.31

-3.06

QNDPRSPL

8.49

-4.15

-2.90

NQNDPRSP

11.55

-1.00

0.25

 


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