ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-12.PDB
Scoring matrix: LSB3_2A08-12_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.76
Foldx random average score for Saccharomyces cerevisiae: 13.531

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181395
Proteins after random average filtering: 5078
 Total fragments: 894432
Proteins after disorder filtering: 3086
 Total fragments: 50707
Proteins after pattern filtering: 1514
 Total fragments: 9522
Proteins after MINT filtering: 51
 Total fragments: 677


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.76

-1.44

0.00
Best peptides

RRFRRRRK

0.00

-8.35

-6.91
         
Interactors      
Q06604

PRMPSRGR

6.07

-8.95

-7.51

PSPPAKRI

6.36

-5.48

-4.04

FEKGPRMP

7.01

-8.08

-6.64
P09119

SAQVPLTP

12.26

-3.39

-1.95

MSAIPITP

12.38

-3.73

-2.29

PTTSPVKK

13.01

-2.45

-1.01
P25604

KSPHLKPP

8.54

-3.16

-1.72

LPPKPKSP

8.81

-3.74

-2.30

HLKPPLPP

9.98

-4.35

-2.91
P40325

PRPPPRPQ

4.70

-8.10

-6.66

QSQPPRPP

6.46

-6.91

-5.47

PPRPPRPA

6.52

-8.58

-7.14
Q12532

PFKPYING

11.66

-4.26

-2.82
Q04322

QAPLDRPQ

7.00

-5.61

-4.17

PTLPPRRI

8.76

-7.83

-6.39

NATPSKSP

9.45

-3.47

-2.03
P38266

PPKPFRRS

6.48

-8.91

-7.47

FLPPPKPF

6.73

-4.70

-3.26

FQPPPKPF

6.76

-4.99

-3.55
P15891

PPPPPRRA

6.36

-7.12

-5.68

ATPEKKPK

7.09

-4.61

-3.17

RATPEKKP

7.64

-3.79

-2.35
P53169

PTLPPRPY

9.38

-7.95

-6.51

PIMPTLPP

11.51

-5.31

-3.87

NSVPIMPT

11.75

-3.58

-2.14
Q12344

PKLPPRGK

8.97

-8.19

-6.75

TSTSPKLP

9.67

-4.03

-2.59

SSPPLPPR

10.91

-2.87

-1.43
P40494

KSRPPRPP

5.29

-8.47

-7.03

PRPPPKPL

5.40

-4.69

-3.25

RPPRPPPK

9.29

-2.40

-0.96
P53238

QKPAGRPI

6.32

-5.46

-4.02

GRPIPPAP

10.86

-2.42

-0.98

PAGRPIPP

11.37

-2.93

-1.49
P32660

PTDPNRPK

7.98

-6.49

-5.05

DPNRPKVT

8.74

-4.69

-3.25

TDPNRPKV

11.28

-2.90

-1.46
P38739

PFHDPILP

12.30

-3.93

-2.49

FHDPILPR

12.41

-3.21

-1.77

SPPNDPST

13.28

-1.50

-0.06
Q04749

PVFNPRKP

4.69

-8.67

-7.23

VFNPRKPT

7.96

-5.77

-4.33

LPVLPRRI

8.32

-6.50

-5.06
P38090

CSPNDPDL

12.61

-0.91

0.53
P47129

TLPNRKPN

6.79

-4.54

-3.10

RKPNPPPN

9.15

-2.19

-0.75

NTLPNRKP

9.72

-7.60

-6.16
P40453

LRKRPPPP

8.29

-5.51

-4.07

RKRPPPPP

8.51

-4.55

-3.11

EPPSWKPP

8.97

-3.92

-2.48
P40095

VLPPPRSP

6.87

-6.61

-5.17

PRSPNRPT

7.33

-5.52

-4.08

RSPNRPTL

10.69

-2.35

-0.91
Q12168

QHPVPKPN

7.38

-4.40

-2.96

PPVPNRPG

9.21

-5.94

-4.50

RGPPPLPP

9.32

-3.20

-1.76
P32793

HGPTHPSN

12.84

-1.21

0.23

PTHPSNMS

13.49

-3.40

-1.96

GHGPTHPS

13.49

-2.24

-0.80
P36123

PKTPPRPK

6.08

-5.33

-3.89

TPPRPKTI

7.37

-3.78

-2.34

LYTTPKTP

9.63

-3.36

-1.92
Q08412

PTQPVRKN

7.20

-7.28

-5.84

DVPPQLPT

10.62

-3.38

-1.94

NSRPQQPE

10.69

-4.07

-2.63
P32855

APTLPKRK

8.48

-5.02

-3.58

NAPTLPKR

11.68

-2.22

-0.78

NNAPTLPK

11.78

-2.90

-1.46
Q06409

PRKTPRPP

5.00

-7.81

-6.37

TGKPRKTP

7.40

-6.07

-4.63

GKPRKTPR

9.58

-2.89

-1.45
P32634

PTEPTRYN

7.89

-7.52

-6.08

LPPVPKAP

8.82

-4.07

-2.63

QEKIPLEP

10.99

-3.83

-2.39
P53118

ENPHDLPS

12.60

-2.47

-1.03
Q12199

PATPPRHI

7.77

-6.88

-5.44

TTPSVQPT

12.41

-1.84

-0.40

AAPATPPR

12.45

-2.19

-0.75
P19158

SSPSSPPS

12.31

-1.83

-0.39

MTPVSPLG

12.37

-1.59

-0.15

EYDPSLPD

12.47

-2.23

-0.79
P43638

GRPIPPHP

9.99

-2.73

-1.29

AKGRPIPP

10.21

-2.71

-1.27

HPDAPKLP

11.08

-3.47

-2.03
P53933

TRRRPPPP

8.00

-4.38

-2.94

RRRPPPPP

8.14

-4.99

-3.55

RRPPPPPI

8.78

-3.17

-1.73
P50101

TVFPGSPI

11.76

-2.85

-1.41

VFPGSPID

13.39

-1.88

-0.44
P33400

TSPQILPP

10.68

-2.42

-0.98

ILPPLPVG

12.56

-2.21

-0.77

VQPPNAPS

13.12

-1.65

-0.21
P38238

QSPTNPPY

12.18

-1.61

-0.17
Q06116

PELVPRSS

10.37

-7.71

-6.27

GVKPFYPV

11.18

-3.83

-2.39

NSPELVPR

11.96

-1.58

-0.14
Q08229

YNPTIPPR

11.97

-1.64

-0.20

DYNPTIPP

12.28

-3.82

-2.38

TRPLPSTP

12.30

-0.77

0.67
P38930

PDMVPKHP

8.08

-6.87

-5.43

QAFPDMVP

10.02

-4.46

-3.02

DMVPKHPT

12.11

-2.99

-1.55
Q12446

PPPPPRRG

6.39

-7.11

-5.67

PPPPHRHV

6.92

-6.93

-5.49

PPPPRRGP

7.75

-6.11

-4.67
P32790

PIKPPRPT

5.77

-7.43

-5.99

PAMPARPT

7.33

-7.20

-5.76

PLDPFKTG

10.27

-3.49

-2.05
P33336

DRNLPSHP

12.77

-1.70

-0.26

CDPEDYPT

12.80

-2.62

-1.18

NLPSHPSS

13.09

-2.45

-1.01
P40041

KIPLSPPS

11.84

-2.56

-1.12

GRTLPPVP

12.62

-1.63

-0.19
P50942

PCPPIRRK

5.40

-6.76

-5.32

STKPEKPP

6.71

-6.03

-4.59

RPCPPIRR

9.90

-4.72

-3.28
P47030

ETKPPRAP

6.36

-8.39

-6.95

EAFPPEPS

11.79

-2.67

-1.23

AFPPEPSM

12.31

-2.36

-0.92
P40563

PSERPKRR

4.83

-5.23

-3.79

PPPVPKKP

7.88

-4.51

-3.07

SEVTPKVP

9.30

-3.87

-2.43
P40528

PLPYPIAQ

12.03

-2.84

-1.40

DIPITPSH

12.80

-2.48

-1.04

PITPSHDN

13.50

-2.53

-1.09
Q12134

PVPSPMNS

11.84

-2.40

-0.96

HQPVPSPM

12.99

-1.55

-0.11

THQPVPSP

13.45

-2.55

-1.11
P53901

GLNSPKLP

9.81

-4.65

-3.21

MAMRPIPP

9.98

-5.08

-3.64

SSPNSHPH

10.39

-1.93

-0.49
P31374

DFEQPRLP

7.15

-7.26

-5.82

NISPERPS

8.47

-5.34

-3.90

PERPSFRQ

9.40

-4.30

-2.86
P38870

PERPKRKS

4.99

-7.76

-6.32

TPERPKRK

5.84

-5.36

-3.92

PTTPERPK

7.34

-5.84

-4.40
Q07660

SAFKPIGP

10.78

-4.00

-2.56
P53955

NQNDPRSP

9.53

-6.02

-4.58

RNPIPYPI

10.64

-2.42

-0.98

QRNPIPYP

12.26

-3.97

-2.53

 


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