ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1SSH-7.PDB
Scoring matrix: LSB3_1SSH-7_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 14.55
Foldx random average score for Saccharomyces cerevisiae: 11.906

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181395
Proteins after random average filtering: 5078
 Total fragments: 985495
Proteins after disorder filtering: 3173
 Total fragments: 50632
Proteins after pattern filtering: 1525
 Total fragments: 9649
Proteins after MINT filtering: 50
 Total fragments: 677


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

14.55

-3.48

0.00
Best peptides

MMRRTPRR

0.00

-10.65

-7.17
         
Interactors      
Q06604

GPRMPSRG

6.46

-11.91

-8.43

PPLPTRRD

6.68

-10.82

-7.34

PPPLPTRR

7.26

-13.33

-9.85
P09119

MSAIPITP

9.85

-6.99

-3.51

PTTSPVKK

10.59

-6.02

-2.54

VPLTPTTS

11.40

-6.21

-2.73
P25604

KPKSPHLK

8.10

-7.23

-3.75

PHLKPPLP

8.96

-7.98

-4.50

PLPPKPKS

9.05

-6.42

-2.94
P40325

QPPRPPRP

4.25

-11.98

-8.50

QPRPPPRP

6.24

-12.76

-9.28

PWTYPPRF

6.29

-10.95

-7.47
Q04322

PPTLPPRR

7.21

-13.34

-9.86

PTLPPRRI

7.47

-11.38

-7.90

SPPLPPRA

7.60

-10.97

-7.49
P38266

PPPKPFRR

4.82

-13.77

-10.29

PPPKPFRH

5.03

-13.52

-10.04

PRPPPSRS

5.34

-11.84

-8.36
P15891

APPPPPRR

5.38

-12.78

-9.30

PPPPPRRA

6.20

-12.74

-9.26

QPPLPSRN

7.83

-11.88

-8.40
P53169

MPTLPPRP

7.01

-12.88

-9.40

VPIMPTLP

8.10

-9.45

-5.97

IMPTLPPR

8.37

-6.69

-3.21
Q12344

SPPLPPRQ

7.50

-11.76

-8.28

SPKLPPRG

7.82

-11.08

-7.60

TSPKLPPR

9.53

-5.70

-2.22
P40494

DKSRPPRP

5.31

-7.43

-3.95

RPPRPPPK

7.05

-7.28

-3.80

RPPPKPLH

8.10

-7.58

-4.10
P53238

PPAPTHYN

9.17

-6.43

-2.95

IPPAPTHY

9.82

-4.76

-1.28

PAGRPIPP

10.31

-6.56

-3.08
P32660

DPNRPKVT

8.64

-5.86

-2.38

TDPNRPKV

8.94

-5.41

-1.93

DPTDPNRP

9.26

-9.69

-6.21
P38739

SPFHDPIL

10.56

-3.47

0.01

PFHDPILP

11.16

-6.79

-3.31

FHDPILPR

11.63

-6.05

-2.57
Q04749

PLPVLPRR

4.90

-13.03

-9.55

NPVFNPRK

5.61

-11.05

-7.57

NPRKPTLS

8.04

-7.68

-4.20
P38090

SPNDPDLT

10.71

-5.51

-2.03
P47129

PNPPPNRS

7.39

-11.42

-7.94

PPLLPPRN

7.77

-13.99

-10.51

KPNPPPNR

8.71

-6.99

-3.51
P40453

PDLPIRLR

7.87

-8.83

-5.35

VPEPPSWK

8.14

-8.27

-4.79

PPDLPIRL

8.27

-13.07

-9.59
P40095

PVLPPPRS

7.08

-11.94

-8.46

SPNRPTLS

7.15

-6.57

-3.09

PPRSPNRP

7.87

-11.48

-8.00
Q12168

PPPVPNRP

6.62

-12.69

-9.21

PPPLPPRA

7.36

-12.73

-9.25

DPYFPQFR

7.88

-7.11

-3.63
P32793

PTHPSNMS

11.64

-5.59

-2.11

GPTHPSNM

11.67

-4.86

-1.38
P36123

PDHFPSRS

4.68

-12.92

-9.44

TPKTPPRP

6.96

-9.41

-5.93

TPPRPKTI

7.81

-5.74

-2.26
Q08412

LPTQPVRK

7.86

-12.16

-8.68

VPPQLPTR

8.02

-7.22

-3.74

PLPPEPLD

8.12

-6.24

-2.76
P32855

APTLPKRK

7.77

-11.95

-8.47

NAPTLPKR

9.85

-5.99

-2.51

TNNAPTLP

11.06

-5.95

-2.47
Q06409

KPRKTPRP

4.21

-10.94

-7.46

KTPRPPFP

6.77

-6.78

-3.30

PRNPDPYG

9.75

-4.99

-1.51
P32634

VPTEPTRY

7.05

-11.21

-7.73

PLPPVPKA

8.62

-8.81

-5.33

YPLNLPIV

8.96

-6.25

-2.77
P53118

VENPHDLP

10.76

-5.14

-1.66
Q12199

APATPPRH

6.65

-11.46

-7.98

PNNPQCLH

10.65

-6.13

-2.65

AAPATPPR

10.98

-5.41

-1.93
P19158

MTPVSPLG

9.34

-5.36

-1.88

PVSPLGLD

10.08

-5.88

-2.40

SMTPVSPL

10.50

-6.62

-3.14
P43638

GRPIPPHP

9.47

-6.21

-2.73

KGRPIPPH

9.48

-7.37

-3.89

PTNIPPPR

9.89

-7.20

-3.72
P53933

TRRRPPPP

7.15

-5.97

-2.49

PPPLPNRQ

7.85

-13.02

-9.54

RRPPPPPI

8.76

-6.32

-2.84
P50101

PGSPIDKS

10.42

-6.77

-3.29
P33400

ILPPLPVG

8.96

-4.76

-1.28

SPQILPPL

10.22

-4.99

-1.51

PPNAPSYQ

10.24

-7.06

-3.58
P38238

SPTNPPYK

9.64

-5.15

-1.67

VQSPTNPP

11.47

-5.23

-1.75

DPVQSPTN

11.82

-3.12

0.36
Q06116

SEPVEPFS

8.80

-5.76

-2.28

SPELVPRS

8.90

-11.62

-8.14

KPFYPVTS

9.31

-6.22

-2.74
Q08229

NPTIPPRS

6.11

-11.75

-8.27

YNPTIPPR

9.48

-7.86

-4.38

TPVQPGGH

10.40

-5.20

-1.72
P38930

FPDMVPKH

8.22

-10.79

-7.31

PDMVPKHP

10.23

-8.21

-4.73

DMVPKHPT

11.36

-5.33

-1.85
Q12446

APPPPPRR

5.38

-12.78

-9.30

PPPPPHRH

5.77

-13.30

-9.82

APPPPPRA

6.09

-11.70

-8.22
P32790

PPIKPPRP

6.02

-12.62

-9.14

PPAMPARP

6.11

-13.43

-9.95

KPPRPTST

8.17

-6.52

-3.04
P33336

TCDPEDYP

11.39

-2.81

0.67
P40041

PLSPPSSS

11.09

-6.24

-2.76

IPLSPPSS

11.56

-3.35

0.13
P50942

PPPPTSRH

5.40

-11.67

-8.19

RPCPPIRR

6.10

-11.81

-8.33

PCPPIRRK

6.40

-11.58

-8.10
P47030

FPPEPSMS

9.25

-9.17

-5.69

DEAFPPEP

9.94

-6.04

-2.56

ANNPLDKP

11.43

-5.77

-2.29
P40563

PSERPKRR

4.39

-12.34

-8.86

TPKVPERP

6.70

-10.79

-7.31

APPPVPKK

8.55

-8.35

-4.87
P40528

PLPYPIAQ

9.87

-5.14

-1.66

DIPITPSH

9.98

-5.33

-1.85

IPITPSHD

10.64

-3.62

-0.14
Q12134

QPVPSPMN

10.47

-6.32

-2.84

HQPVPSPM

11.66

-6.02

-2.54
P53901

MRPIPPLP

5.11

-8.84

-5.36

LPPIPTRD

8.84

-12.15

-8.67

MAMRPIPP

8.86

-7.32

-3.84
P39743

YSNPLTSP

11.72

-4.93

-1.45
P31374

SPERPSFR

6.72

-6.87

-3.39

TPVFPNLD

7.65

-6.72

-3.24

PERPSFRQ

8.12

-10.66

-7.18
P38870

TPERPKRK

3.70

-10.25

-6.77

TPTTPERP

7.95

-9.62

-6.14

TTPERPKR

9.40

-4.70

-1.22
P53955

QRNPIPYP

8.92

-4.86

-1.38

RNPIPYPI

10.39

-6.24

-2.76

PIPYPIDA

11.30

-5.40

-1.92

 


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