ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKB-17.PDB
Scoring matrix: LSB1_1CKB-17_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.19
Foldx random average score for Saccharomyces cerevisiae: 17.644

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207309
Proteins after random average filtering: 7178
 Total fragments: 1329985
Proteins after disorder filtering: 4481
 Total fragments: 60905
Proteins after pattern filtering: 1920
 Total fragments: 6547
Proteins after MINT filtering: 27
 Total fragments: 204


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.19

-3.34

0.00

Best peptides

RRYIWGWSL

0.00

-8.64

-5.31

         
Interactors      
Q06604

GPRMPSRGR

13.91

-5.41

-2.08

YSNIPSSKP

14.96

-8.29

-4.95

PAPPVSRST

15.23

-6.11

-2.78

P53120

RSYEPECPV

15.02

-4.14

-0.80

Q04322

GNATPSKSP

16.54

-5.52

-2.18

P19812

NSPEASPSL

14.78

-4.04

-0.71

HSPIFRPGN

15.33

-4.80

-1.46

PRPRRIPPT

17.63

-7.61

-4.28

P53169

SPAQPSASL

15.09

-6.12

-2.79

NSVPIMPTL

15.52

-6.42

-3.09

VPIMPTLPP

15.87

-7.48

-4.15

Q12344

PPLPPRQNV

16.15

-7.45

-4.12

PKLPPRGKQ

16.32

-6.27

-2.93

P00812

PHCPESLKW

15.83

-7.11

-3.78

VPHCPESLK

16.48

-6.00

-2.67

NKDVPHCPE

16.89

-4.24

-0.91

P53238

RPIPPAPTH

11.07

-10.99

-7.66

IPPAPTHYN

16.62

-6.79

-3.46

PPAPTHYNN

16.91

-7.74

-4.41

P08417

PENEPGSSI

14.04

-5.79

-2.46

P39521

TPHVPDRPP

15.37

-8.04

-4.70

P04050

PPPPVRPSI

12.50

-9.15

-5.82

PPVRPSISF

13.15

-7.79

-4.46

SPTSPGYSP

14.64

-6.55

-3.21

P40453

VPEPPSWKP

15.22

-8.27

-4.93

PDLPIRLRK

15.60

-5.50

-2.17

PPPVSMPTT

16.00

-6.37

-3.04

Q12168

VPNRPGGTT

14.20

-5.90

-2.57

QHPVPKPNI

14.21

-6.67

-3.34

RGPPPLPPR

14.53

-9.20

-5.86

Q03780

PPPPMDMKS

15.13

-7.79

-4.46

PPPPPMDMK

16.39

-8.04

-4.70

PPRSPNRNA

17.63

-7.96

-4.63

P48582

RNTPPQPSL

9.39

-9.60

-6.26

PPLPPLDSK

15.00

-6.98

-3.65

SDLPQGPGI

15.62

-5.96

-2.63

P53933

PPPIPSTQK

14.96

-5.77

-2.43

PPPPPIPST

15.60

-7.74

-4.41

PPPLPNRQL

17.00

-9.20

-5.86

Q08229

RPLPSTPNE

12.25

-8.49

-5.16

TPVQPGGHY

12.90

-8.10

-4.76

PVQPGGHYK

13.72

-5.62

-2.29

P33338

RTPARTPTP

14.38

-9.37

-6.03

RTPTPTPPV

14.84

-7.49

-4.16

P32893

NGTIPNSPL

16.71

-4.70

-1.37

Q12446

RPLPQLPNR

11.31

-11.17

-7.84

PPPPPHRHV

12.94

-8.13

-4.80

FPIPEIPST

13.47

-7.22

-3.88

P39940

WDDPRLPSS

14.90

-5.62

-2.29

P38266

PPKPFRRSQ

11.75

-9.33

-6.00

PRPPPSRSS

13.57

-7.41

-4.08

RKRAPTPPA

13.94

-9.95

-6.61

P40483

PSVPPRNYF

16.32

-6.54

-3.21

P40563

NSQPQGPSD

14.05

-6.17

-2.84

RAPPPVPKK

14.22

-9.43

-6.09

PSERPKRRA

16.78

-5.35

-2.01

Q07533

PHFPYGTWK

12.57

-7.16

-3.83

IPPVPSRYS

13.45

-6.38

-3.04

PPVPSRYSD

14.63

-7.72

-4.38

Q04195

RGNEPIQFP

14.26

-8.61

-5.27

NEPIQFPFP

14.93

-6.95

-3.62

PQNVPIRTN

14.95

-6.56

-3.22

P43582

WPRPKGPPP

14.62

-10.44

-7.10

 


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