ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKB-12.PDB
Scoring matrix: LSB1_1CKB-12_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.47
Foldx random average score for Saccharomyces cerevisiae: 9.958

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214487
Proteins after random average filtering: 7178
 Total fragments: 1300186
Proteins after disorder filtering: 4538
 Total fragments: 76073
Proteins after pattern filtering: 2230
 Total fragments: 13227
Proteins after MINT filtering: 26
 Total fragments: 497


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.47

-0.87

0.00

Best peptides

RRFRPFWR

0.00

-3.42

-2.55

         
Interactors      
Q06604

PSPPAKRI

4.55

-4.65

-3.78

FEKGPRMP

5.53

-3.29

-2.42

SSPPPLPT

5.75

-5.26

-4.39

P53120

YEPECPVA

9.61

-1.92

-1.05

RSYEPECP

9.64

-1.52

-0.65

Q04322

QAPLDRPQ

6.43

-3.72

-2.85

STPPTLPP

6.48

-5.00

-4.13

TSPPLPPR

7.29

-3.58

-2.71

P19812

HSPIFRPG

5.34

-3.82

-2.95

PRPRRIPP

5.43

-4.76

-3.89

DHSPIFRP

6.26

-3.95

-3.08

P53169

PIMPTLPP

7.44

-5.78

-4.91

IMPTLPPR

7.92

-1.82

-0.95

SVPIMPTL

8.78

-2.36

-1.49

Q12344

PLPPRQNV

6.44

-4.26

-3.39

TSPKLPPR

7.16

-3.55

-2.68

SSPPLPPR

7.31

-3.60

-2.73

Q07533

SSPKSPKA

6.82

-3.34

-2.47

KSPKAYPK

6.91

-3.80

-2.93

KSDPHFPY

7.10

-3.42

-2.55

P53238

QKPAGRPI

5.83

-4.27

-3.40

GRPIPPAP

7.25

-3.43

-2.56

PIPPAPTH

8.64

-3.25

-2.38

P39521

AQPKPKPA

5.41

-5.15

-4.28

PKPKPAQD

8.02

-1.60

-0.73

DAQPKPKP

8.12

-3.09

-2.22

P04050

PAYSPKQD

6.39

-3.63

-2.76

PPPPVRPS

6.87

-5.13

-4.26

VPPPPVRP

7.55

-3.28

-2.41

P40453

PEPPSWKP

4.96

-5.29

-4.42

WKPPDLPI

5.37

-5.24

-4.37

EIPPPLPP

5.62

-5.17

-4.30

Q12168

PYFPQFRS

2.83

-5.54

-4.67

RGPPPLPP

5.93

-4.55

-3.68

QHPVPKPN

6.76

-2.86

-1.99

Q03780

SRPPPPPM

6.54

-3.82

-2.95

PRSPNRNA

7.38

-2.69

-1.82

RSRPPPPP

7.87

-3.23

-2.36

P48582

GGPPLLPQ

6.55

-5.04

-4.17

PVPPKQSQ

7.08

-4.37

-3.50

PAPPLPPL

8.15

-3.47

-2.60

Q04659

KDPTVPNG

9.82

-1.92

-1.05

P53933

DLPMELPH

5.96

-5.64

-4.77

VAPPPLPN

6.04

-5.23

-4.36

RRPPPPPI

6.45

-4.06

-3.19

Q08229

YNPTIPPR

8.68

-2.28

-1.41

TRPLPSTP

8.96

-2.16

-1.29

DYNPTIPP

9.01

-3.01

-2.14

P33338

ARTPARTP

8.21

-3.14

-2.27

SWSGPLTP

8.58

-2.44

-1.57

RTPTPTPP

8.89

-2.32

-1.45

P43582

TWPRPKGP

4.87

-4.47

-3.60

PRPKGPPP

6.87

-3.24

-2.37

KSNPPQVP

8.14

-2.50

-1.63

P39940

DDPRLPSS

8.37

-2.17

-1.30

TWDDPRLP

8.50

-3.07

-2.20

WDDPRLPS

8.53

-1.87

-1.00

P38266

PPPKPFRR

3.88

-5.39

-4.52

PPPKPFRH

4.26

-5.07

-4.20

IMPPPKPF

4.80

-4.48

-3.61

P40483

DAPASKPS

6.97

-2.46

-1.59

SKPSVPPR

7.61

-2.77

-1.90

PSVPPRNY

8.74

-5.03

-4.16

P40563

PSERPKRR

4.05

-4.56

-3.69

PPPVPKKP

6.87

-2.71

-1.84

VNPGQLPP

7.00

-4.24

-3.37

P00812

VDPLYIPA

8.58

-2.63

-1.76

PLYIPATG

8.79

-2.75

-1.88

NKDVPHCP

9.32

-3.12

-2.25

Q04195

NEPIQFPF

4.16

-5.35

-4.48

GNEPIQFP

8.00

-2.67

-1.80

RAPPPTNP

8.68

-2.80

-1.93

Q12446

PPPPPRRG

4.98

-4.98

-4.11

PPPPPHRH

5.18

-5.81

-4.94

PPPPPMRT

5.64

-5.85

-4.98

 


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