ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKA-7.PDB
Scoring matrix: LSB1_1CKA-7_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.02
Foldx random average score for Saccharomyces cerevisiae: 8.832

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214487
Proteins after random average filtering: 7178
 Total fragments: 1289748
Proteins after disorder filtering: 4337
 Total fragments: 57359
Proteins after pattern filtering: 2168
 Total fragments: 13012
Proteins after MINT filtering: 26
 Total fragments: 472


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.02

-3.19

0.00

Best peptides

VMPMPPMM

0.00

-2.49

0.70

         
Interactors      
Q06604

PPPLPTRR

3.79

-7.77

-4.58

PPSPPAKR

4.29

-6.87

-3.68

VKPAPPVS

4.69

-6.96

-3.77

P53120

RSYEPECP

8.24

-5.06

-1.87

YEPECPVA

8.71

-2.88

0.31

Q04322

PPTLPPRR

3.77

-7.84

-4.65

SPPLPPRA

4.77

-6.43

-3.24

PTLPPRRI

5.85

-7.69

-4.50

P19812

PQNPPPIL

5.86

-6.79

-3.60

EPRPRRIP

6.32

-6.43

-3.24

RPRRIPPT

6.87

-7.42

-4.23

P53169

VPIMPTLP

4.60

-7.84

-4.65

MPTLPPRP

4.95

-8.56

-5.37

IMPTLPPR

5.82

-6.71

-3.52

Q12344

SPPLPPRQ

4.69

-6.89

-3.70

SPKLPPRG

4.96

-6.33

-3.14

PPLPPRQN

5.66

-7.41

-4.22

Q07533

IPPVPSRY

4.41

-7.12

-3.93

PKAYPKLP

5.82

-7.55

-4.36

VKSDPHFP

5.91

-7.66

-4.47

P53238

IPPAPTHY

4.53

-8.34

-5.15

RPIPPAPT

6.01

-5.85

-2.66

KPAGRPIP

6.90

-6.11

-2.92

P39521

PKPKPAQD

5.11

-7.19

-4.00

VPDRPPSQ

5.27

-5.78

-2.59

PDRPPSQL

5.91

-6.95

-3.76

P04050

VPPPPVRP

4.29

-7.47

-4.28

PVPPPPVR

4.95

-6.61

-3.42

PPVRPSIS

5.95

-6.57

-3.38

P40453

VPEPPSWK

3.37

-7.02

-3.83

PPPLPPKI

4.51

-7.23

-4.04

PPDLPIRL

4.88

-7.04

-3.85

Q12168

PPPLPPRA

4.33

-7.98

-4.79

DPYFPQFR

5.08

-6.09

-2.90

NRGPPPLP

5.76

-7.50

-4.31

Q03780

RPPPPPMD

3.23

-8.25

-5.06

SRPPPPPM

4.79

-6.98

-3.79

KRSRPPPP

5.71

-7.52

-4.33

P48582

APPLPPLD

4.56

-6.79

-3.60

APPVPPKQ

5.69

-6.80

-3.61

VGGPPLLP

5.82

-6.93

-3.74

Q04659

VQKDPTVP

8.32

-5.16

-1.97

P53933

RRPPPPPI

4.42

-7.53

-4.34

RPPPPPIP

4.51

-6.97

-3.78

PPPLPNRQ

4.86

-7.01

-3.82

Q08229

TRPLPSTP

6.13

-6.47

-3.28

NPTIPPRS

7.45

-7.03

-3.84

PTIPPRSK

7.69

-5.65

-2.46

P33338

TPTPPVVA

6.01

-5.03

-1.84

VTPARTPA

6.99

-4.98

-1.79

PARTPART

7.31

-6.43

-3.24

P43582

PKGPPPGV

6.93

-6.01

-2.82

RPKGPPPG

6.98

-5.45

-2.26

KSNPPQVP

7.16

-6.81

-3.62

P39940

WDDPRLPS

6.69

-4.72

-1.53

DPRLPSSL

7.45

-4.38

-1.19

PRLPSSLD

7.67

-5.23

-2.04

P38266

VPILPPRN

3.35

-7.42

-4.23

MPPPKPFR

3.41

-7.17

-3.98

IMPPPKPF

3.75

-6.60

-3.41

P40483

KPSVPPRN

4.67

-8.15

-4.96

PSVPPRNY

7.37

-6.21

-3.02

PASKPSVP

7.99

-5.78

-2.59

P40563

PSERPKRR

4.81

-7.74

-4.55

RRAPPPVP

5.39

-7.48

-4.29

RAPPPVPK

5.73

-5.85

-2.66

P00812

VDPLYIPA

7.17

-4.59

-1.40

VPHCPESL

7.32

-5.02

-1.83

KDVPHCPE

7.33

-4.73

-1.54

Q04195

VPNPPNTA

5.55

-5.56

-2.37

TPVLPTLP

6.05

-5.44

-2.25

VLPTLPQN

6.15

-7.16

-3.97

Q12446

VPPPPPMR

1.55

-8.92

-5.73

APPPPPRR

3.23

-7.29

-4.10

APPPPPHR

3.49

-8.53

-5.34

 


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