ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKA-17.PDB
Scoring matrix: LSB1_1CKA-17_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.77
Foldx random average score for Saccharomyces cerevisiae: 16.205

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207309
Proteins after random average filtering: 7178
 Total fragments: 1477141
Proteins after disorder filtering: 4558
 Total fragments: 71321
Proteins after pattern filtering: 2127
 Total fragments: 9395
Proteins after MINT filtering: 28
 Total fragments: 275


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.77

-1.98

0.00

Best peptides

YRWINGRWL

0.00

-2.06

-0.08

         
Interactors      
Q06604

PPSPPAKRI

11.24

-8.16

-6.19

LPTRPNKAE

11.61

-7.23

-5.26

KPTPPSPPA

12.56

-7.85

-5.88

P53120

RSYEPECPV

13.85

-4.59

-2.61

Q04322

DQAPLDRPQ

15.15

-5.38

-3.40

STPPTLPPR

15.64

-4.84

-2.86

PSKSPTSAV

16.15

-4.13

-2.15

Q12168

QHPVPKPNI

9.69

-7.43

-5.46

RGPPPLPPR

12.26

-7.78

-5.80

PPLPPRANV

12.50

-8.67

-6.70

P53169

SPAQPSASL

13.31

-6.92

-4.95

NSVPIMPTL

14.37

-5.38

-3.40

ANSVPIMPT

14.56

-3.90

-1.92

Q12344

PKLPPRGKQ

12.48

-5.98

-4.01

PPLPPRQNV

12.70

-8.52

-6.54

TSSPPLPPR

14.70

-6.20

-4.22

Q07533

PHFPYGTWK

9.68

-6.27

-4.29

IPPVPSRYS

10.68

-6.63

-4.65

KSPKAYPKL

11.07

-6.41

-4.44

P53238

RPIPPAPTH

12.21

-8.12

-6.14

IPPAPTHYN

13.62

-8.61

-6.63

PPAPTHYNN

15.00

-6.04

-4.06

P08417

PENEPGSSI

12.52

-4.72

-2.74

MLPENEPGS

14.53

-4.75

-2.77

P39521

AQPKPKPAQ

13.46

-4.94

-2.97

TPHVPDRPP

14.72

-6.68

-4.71

PHVPDRPPS

15.87

-5.15

-3.18

P04050

PPPPVRPSI

11.83

-8.67

-6.70

PPVRPSISF

12.24

-6.70

-4.72

APTSPGFGV

13.13

-4.23

-2.26

P40453

SWKPPDLPI

12.29

-6.38

-4.40

PDLPIRLRK

12.51

-5.47

-3.49

EIPPPLPPK

14.18

-7.95

-5.97

P19812

PRPRRIPPT

13.91

-5.77

-3.79

HSPIFRPGN

14.34

-6.02

-4.04

NSPEASPSL

14.85

-3.95

-1.98

Q03780

PPPPMDMKS

12.34

-7.67

-5.70

PRSPNRNAH

12.37

-5.58

-3.61

PPPPPMDMK

12.69

-8.02

-6.04

P48582

SDLPQGPGI

11.28

-4.55

-2.57

RNTPPQPSL

11.38

-8.38

-6.41

SPAPPLPPL

12.24

-8.65

-6.68

P53933

PPPIPSTQK

12.29

-7.31

-5.33

VAPPPLPNR

13.86

-6.82

-4.85

NDLPMELPH

14.32

-3.48

-1.50

Q08229

TPVQPGGHY

10.88

-7.32

-5.35

RPLPSTPNE

11.65

-6.78

-4.80

PVQPGGHYK

11.79

-5.80

-3.82

P33338

RTPTPTPPV

12.31

-5.17

-3.19

VTPARTPAR

13.50

-5.01

-3.03

ARTPARTPT

15.08

-4.79

-2.81

P32893

NGTIPNSPL

13.47

-5.47

-3.49

Q12446

RPLPQLPNR

9.90

-7.83

-5.86

PPPPPHRHV

10.60

-9.22

-7.25

APTTPAPAL

11.55

-7.36

-5.38

P40483

PSVPPRNYF

12.21

-6.39

-4.41

KPSVPPRNY

14.62

-9.29

-7.31

KDAPASKPS

15.67

-3.41

-1.44

P39940

WDDPRLPSS

13.95

-4.55

-2.57

PRLPSSLDQ

14.52

-1.87

0.10

TWDDPRLPS

15.70

-3.02

-1.04

P38266

FQPPPKPFR

9.73

-9.00

-7.03

FLPPPKPFR

9.88

-8.41

-6.44

QPPVPVRMQ

11.27

-7.36

-5.38

Q04659

PTVPNGLDG

13.73

-2.27

-0.29

DPTVPNGLD

16.11

-5.41

-3.44

P40563

RAPPPVPKK

12.84

-7.74

-5.77

PSERPKRRA

13.19

-6.00

-4.03

PPPVPKKPS

13.74

-6.48

-4.51

P00812

PHCPESLKW

12.17

-3.90

-1.92

NKDVPHCPE

14.14

-3.99

-2.02

PLYIPATGT

15.32

-3.03

-1.05

Q04195

NEPIQFPFP

13.92

-6.33

-4.36

PSEPIIINL

14.16

-6.50

-4.53

PTLPQNVPI

14.44

-5.26

-3.28

P43582

WPRPKGPPP

12.22

-7.61

-5.63

 


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