ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKA-11.PDB
Scoring matrix: LSB1_1CKA-11_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.58
Foldx random average score for Saccharomyces cerevisiae: 9.267

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221665
Proteins after random average filtering: 7178
 Total fragments: 1369523
Proteins after disorder filtering: 4710
 Total fragments: 90814
Proteins after pattern filtering: 2305
 Total fragments: 14402
Proteins after MINT filtering: 28
 Total fragments: 549


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.58

-2.06

0.00

Best peptides

YPPIRRL

0.00

-4.23

-2.17

         
Interactors      
Q06604

LPTRPNK

4.99

-6.29

-4.23

GPRMPSR

5.04

-6.22

-4.16

PPPLPTR

5.58

-8.01

-5.95

P53120

EPECPVA

7.65

-5.50

-3.44

YEPECPV

7.71

-4.35

-2.29

Q04322

SPPLPPR

5.55

-7.04

-4.98

PPTLPPR

5.58

-8.11

-6.05

PLDRPQL

6.11

-5.76

-3.70

Q12168

PPPLPPR

4.92

-8.64

-6.58

PPPVPNR

5.55

-6.59

-4.53

VPNRPGG

6.12

-5.60

-3.54

P53169

VPIMPTL

4.17

-6.18

-4.12

MPTLPPR

4.51

-8.13

-6.07

TLPPRPY

7.08

-4.51

-2.45

Q12344

SPPLPPR

5.55

-7.04

-4.98

SPKLPPR

5.85

-6.93

-4.87

PPLPPRQ

6.01

-6.87

-4.81

Q07533

LPPLPPL

4.09

-8.15

-6.09

IPPVPSR

4.45

-5.55

-3.49

LPPLPDL

4.62

-7.75

-5.69

P53238

RPIPPAP

5.44

-7.92

-5.86

KPAGRPI

5.89

-6.61

-4.55

GRPIPPA

6.03

-4.88

-2.82

P08417

MLPENEP

8.47

-5.30

-3.24

LPENEPG

8.64

-4.33

-2.27

PENEPGS

9.11

-3.69

-1.63

P39521

VPDRPPS

5.58

-5.36

-3.30

PKPKPAQ

6.33

-4.84

-2.78

PDRPPSQ

6.38

-4.71

-2.65

P04050

VPPPPVR

5.17

-6.63

-4.57

PPVRPSI

5.25

-7.76

-5.70

LPVPPPP

5.62

-7.46

-5.40

P40453

RPPPPPP

4.46

-8.68

-6.62

PPPLPPK

4.92

-8.12

-6.06

TPEIPPP

5.12

-6.44

-4.38

P19812

PRRIPPT

5.06

-6.02

-3.96

PRPRRIP

5.13

-5.60

-3.54

RPRRIPP

5.32

-8.18

-6.12

Q03780

RPPPPPM

3.88

-8.59

-6.53

APDIPPR

4.18

-6.40

-4.34

RSRPPPP

5.96

-6.11

-4.05

P48582

APPLPPL

4.44

-7.92

-5.86

TPPQPSL

4.75

-4.86

-2.80

GPGIPPR

4.90

-5.65

-3.59

P53933

RPPPPPI

4.33

-8.77

-6.71

PPPIPST

4.67

-6.59

-4.53

RRPPPPP

4.88

-6.66

-4.60

Q08229

NPTIPPR

4.17

-6.31

-4.25

YNPTIPP

6.32

-5.47

-3.41

LPSTPNE

7.22

-5.34

-3.28

P33338

GPLTPPT

7.16

-4.93

-2.87

TPTPPVV

7.23

-4.55

-2.49

RTPARTP

7.37

-5.93

-3.87

P32893

TIPNSPL

8.10

-2.79

-0.73

Q12446

PPPRRGP

4.25

-7.59

-5.53

IPEIPST

4.37

-4.70

-2.64

VPPPPPM

4.58

-6.57

-4.51

P40483

KPSVPPR

5.10

-7.57

-5.51

APASKPS

7.26

-4.37

-2.31

PASKPSV

7.46

-5.46

-3.40

P39940

WDDPRLP

6.46

-4.68

-2.62

PRLPSSL

7.32

-4.54

-2.48

DPRLPSS

7.51

-5.01

-2.95

P38266

YPIEPSL

3.08

-7.49

-5.43

FPPPPLK

3.29

-8.51

-6.45

PPPKPFR

4.62

-7.81

-5.75

Q04659

PTVPNGL

7.95

-6.11

-4.05

DPTVPNG

8.62

-5.19

-3.13

KDPTVPN

9.00

-2.85

-0.79

P40563

PPPVPKK

5.25

-7.78

-5.72

PPVPKKP

6.01

-6.95

-4.89

PSERPKR

6.08

-5.98

-3.92

P00812

KDVPHCP

5.78

-5.48

-3.42

PLYIPAT

6.65

-6.98

-4.92

VPHCPES

7.67

-4.32

-2.26

Q04195

TPVLPTL

5.90

-5.71

-3.65

VPNPPNT

6.62

-4.98

-2.92

HPSEPII

6.76

-6.52

-4.46

P43582

RPKGPPP

6.04

-7.49

-5.43

WPRPKGP

6.07

-6.21

-4.15

PKGPPPG

7.26

-6.18

-4.12

 


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