ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-7.PDB
Scoring matrix: HSE1_1SEM-7_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 16.65
Foldx random average score for Saccharomyces cerevisiae: 13.621

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 997768
Proteins after disorder filtering: 3281
 Total fragments: 54491
Proteins after pattern filtering: 1497
 Total fragments: 8423
Proteins after MINT filtering: 19
 Total fragments: 353


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

16.65

-0.63

0.00

Best peptides

IDPRSPKY

0.00

-3.37

-2.74

         
Interactors      
Q06604

LPTRPNKA

6.28

-7.16

-6.53

PPPLPTRR

7.72

-9.87

-9.24

PPSPPAKR

8.96

-6.05

-5.42

Q06108

TDPRSPYY

4.66

-4.69

-4.06

DPPPQPRR

8.69

-6.10

-5.47

PPPQPRRL

9.31

-7.50

-6.87

P40073

YPQQQPSH

12.66

-3.82

-3.19

P25604

PKPKSPHL

9.06

-6.56

-5.93

TPPLPPKP

9.43

-6.41

-5.78

APSLPPKP

9.57

-6.83

-6.20

P40325

QPPRPPRP

7.59

-8.67

-8.04

RPPRPAAN

8.88

-6.36

-5.73

SQPRPPPR

9.65

-6.58

-5.95

O13527

IHPRGIPG

9.41

-4.28

-3.65

PLNPKGKK

9.69

-5.50

-4.87

IPYTPYQM

9.71

-6.07

-5.44

P48524

PLLRPQRS

7.76

-9.32

-8.69

PPKRKPLL

7.89

-7.20

-6.57

PKRKPLLR

9.78

-8.29

-7.66

Q06412

NSPKSPRD

9.19

-6.56

-5.93

FSPNSPKS

9.63

-3.20

-2.57

PPPPPLLY

9.74

-6.34

-5.71

Q66RC5

IPDNPGRL

7.58

-7.38

-6.75

PDNPGRLL

11.33

-5.22

-4.59

P36037

PLKLPINV

11.34

-6.17

-5.54

PPLKLPIN

11.42

-6.15

-5.52

KPPLKLPI

13.29

-6.45

-5.82

P36041

MPPPPGLV

8.73

-6.75

-6.12

MPPLPQGF

8.74

-6.70

-6.07

FFPMHPNF

9.21

-5.34

-4.71

Q04439

IPTPPQNR

9.56

-5.51

-4.88

PPPPSSKP

9.63

-3.86

-3.23

PTPPQNRD

9.68

-5.93

-5.30

P53901

LPPIPTRD

7.78

-8.17

-7.54

MRPIPPLP

8.52

-7.81

-7.18

MAMRPIPP

9.37

-8.25

-7.62

Q12446

LPQLPNRN

8.05

-8.76

-8.13

APPPPPRR

8.57

-8.15

-7.52

LPPLPNQF

8.86

-5.51

-4.88

P40453

PPPLPPKI

7.31

-7.53

-6.90

PPDLPIRL

8.37

-9.01

-8.38

IPPPLPPK

9.19

-4.39

-3.76

P40343

SDPPYPKE

10.09

-4.03

-3.40

SPQPQPIH

11.46

-3.95

-3.32

ELAPSDPP

12.67

-3.61

-2.98

Q03497

IPSRPAPK

6.57

-6.56

-5.93

LPPIPPTK

9.55

-5.87

-5.24

FPSKNPLK

10.28

-5.99

-5.36

P53238

IPPAPTHY

8.33

-5.66

-5.03

RPIPPAPT

12.02

-5.00

-4.37

PAGRPIPP

12.20

-6.14

-5.51

P40041

IPLSPPSS

12.15

-4.49

-3.86

KIPLSPPS

12.88

-5.83

-5.20

PLSPPSSS

13.61

-4.27

-3.64

 


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