ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-5.PDB
Scoring matrix: HSE1_1SEM-5_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.48
Foldx random average score for Saccharomyces cerevisiae: 25.824

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5099
 Total fragments: 1188650
Proteins after disorder filtering: 3190
 Total fragments: 106265
Proteins after pattern filtering: 1627
 Total fragments: 16421
Proteins after MINT filtering: 19
 Total fragments: 537


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.48

5.11

0.00

Best peptides

WFYWPAYPHI

0.00

3.64

-1.47

         
Interactors      
Q06604

PKPTPPSPPA

13.31

-3.50

-8.61

SFEKGPRMPS

13.49

-2.49

-7.60

YSNIPSSKPA

16.34

3.77

-1.34

Q06108

ISKQPATPGS

14.32

-0.71

-5.82

PLMNLPGVSP

15.61

-3.46

-8.57

INMPIPKKLP

16.36

-2.54

-7.65

P40073

QFDGYPQQQP

15.23

-3.66

-8.77

P25604

PHLKPPLPPP

12.69

-6.59

-11.70

PLPPPPPPQP

13.76

-4.64

-9.75

PKPKSPHLKP

14.29

-4.04

-9.15

P40325

PSTMPATSSS

13.43

-0.68

-5.79

QNPSLPWTYP

13.96

-4.00

-9.11

QPPRPPRPAA

14.14

-6.51

-11.62

O13527

NSKIHPRGIP

12.54

-3.82

-8.93

QFPQYPSSVG

12.56

-2.66

-7.77

GKKLRAPGQP

13.44

-3.54

-8.65

P48524

DSGFPPKRKP

16.82

-1.95

-7.06

PPKRKPLLRP

18.94

-7.99

-13.10

RKPLLRPQRS

19.94

-1.67

-6.78

Q06412

NSPKSPRDSS

12.44

-3.29

-8.40

FFTKPPPPLS

13.37

-0.78

-5.89

VKERRPPPPP

15.06

-5.86

-10.97

Q66RC5

PSPLIPDNPG

13.74

-4.09

-9.20

ISNPSPLIPD

18.38

-1.77

-6.88

SISNPSPLIP

19.19

-0.84

-5.95

P36037

PPLKLPINVS

18.04

-2.80

-7.91

GKPPLKLPIN

21.04

-2.02

-7.13

EDGKPPLKLP

21.56

0.18

-4.93

P36041

QQYMPPPPPP

12.93

-4.96

-10.07

PQRMMPPPPG

13.07

-6.18

-11.29

SNSPMPIPSI

13.93

-3.69

-8.80

Q04439

QANIPPPPPP

13.97

-3.78

-8.89

SKPKEPMFEA

14.44

-4.69

-9.80

SNARPSPPTA

14.75

-5.05

-10.16

P53901

PIILPPTFSA

14.53

-3.75

-8.86

NSPKLPPLPT

16.26

-3.62

-8.73

NYNQPPLPPI

16.41

-4.70

-9.81

Q12446

PRRGPAPPPP

12.99

-7.90

-13.01

QSNPFPFPIP

13.76

-2.82

-7.93

QSATNPFPFP

14.22

-2.86

-7.97

P40453

PSWKPPDLPI

11.34

-4.07

-9.18

RLRKRPPPPP

14.69

-5.69

-10.80

PPSWKPPDLP

15.58

-6.18

-11.29

P40343

PSDPPYPKEE

17.37

-2.37

-7.48

PQQPSPQPQP

17.69

-1.37

-6.48

QQPSPQPQPI

17.94

-2.63

-7.74

Q03497

PKVKPSKPEA

13.60

-2.61

-7.72

PSKPEAKSKP

14.73

-3.62

-8.73

PAPKPPSSAS

14.78

-2.24

-7.35

P53238

PIPPAPTHYN

18.36

-3.18

-8.29

QKPAGRPIPP

19.13

-2.71

-7.82

GRPIPPAPTH

20.48

-3.22

-8.33

P40041

KIPLSPPSSS

17.23

-1.15

-6.26

IPLSPPSSSN

18.50

-1.87

-6.98

PNGRTLPPVP

21.00

-3.58

-8.69

 


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