ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-4.PDB
Scoring matrix: HSE1_1SEM-4_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 13.95
Foldx random average score for Saccharomyces cerevisiae: 17.633

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5099
 Total fragments: 1162429
Proteins after disorder filtering: 3157
 Total fragments: 96327
Proteins after pattern filtering: 1622
 Total fragments: 18373
Proteins after MINT filtering: 19
 Total fragments: 604


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

13.95

10.17

0.00

Best peptides

ARPRPPRDPR

0.00

1.22

-8.95

         
Interactors      
Q06604

PTPPSPPAKR

7.01

-2.98

-13.15

RVKPAPPVSR

7.65

-5.05

-15.22

EKPLLPTRPN

8.44

-0.12

-10.29

Q06108

INMPIPKKLP

6.63

-3.66

-13.83

YTIRTPCKSP

7.70

-5.33

-15.50

PRSPYYINMP

9.52

-4.07

-14.24

P40073

QFDGYPQQQP

14.84

-0.40

-10.57

DGYPQQQPSH

16.61

0.69

-9.48

GYPQQQPSHT

17.51

-0.58

-10.75

P25604

PLPPKPKSPH

5.52

-3.37

-13.54

PLPPPPPPQP

6.49

-5.07

-15.24

PHLKPPLPPP

6.84

-6.07

-16.24

P40325

PTSSQPRPPP

6.51

-4.00

-14.17

PLYVQPGDPR

6.85

-3.06

-13.23

SQPRPPPRPQ

8.53

-1.83

-12.00

O13527

PLPDLPPESP

7.60

-3.42

-13.59

PLNPKGKKLR

8.00

-5.66

-15.83

NVPLNPKGKK

8.88

-4.60

-14.77

P48524

PPKRKPLLRP

10.19

-9.32

-19.49

PLLRPQRSDF

10.99

-2.43

-12.60

DSGFPPKRKP

11.10

-1.00

-11.17

Q06412

ERRPPPPPPL

4.71

-3.60

-13.77

VKERRPPPPP

4.93

-6.25

-16.42

RRPPPPPPLL

6.26

-2.48

-12.65

Q66RC5

LIPDNPGRLL

11.16

-2.08

-12.25

ISNPSPLIPD

11.24

-1.41

-11.58

SISNPSPLIP

11.90

-2.19

-12.36

P36037

EDGKPPLKLP

11.43

1.75

-8.42

PPLKLPINVS

12.80

-2.49

-12.66

P36041

ETSTPPPPPP

5.91

-1.76

-11.93

YMPPPPPPGF

8.13

-3.85

-14.02

LRPVIPRGPS

8.15

-3.26

-13.43

Q04439

ANIPPPPPPP

5.20

-4.09

-14.26

NIPPPPPPPP

6.34

-6.35

-16.52

IPPPPPPPPP

6.77

-5.67

-15.84

P53901

AMRPIPPLPT

7.68

-4.00

-14.17

PIILPPTFSA

8.97

-1.40

-11.57

HNYNQPPLPP

8.98

-5.01

-15.18

Q12446

VRLPAPPPPP

4.25

-6.63

-16.80

RLPAPPPPPR

4.76

-1.64

-11.81

RRGPAPPPPP

5.65

-6.09

-16.26

P40453

RLRKRPPPPP

5.09

-6.21

-16.38

LRKRPPPPPP

5.19

-8.44

-18.61

IRLRKRPPPP

5.84

-7.04

-17.21

P40343

HVELAPSDPP

8.34

-3.59

-13.76

LAPSDPPYPK

9.42

-4.17

-14.34

PQQPSPQPQP

10.45

-1.94

-12.11

Q03497

FIPSRPAPKP

6.93

-2.03

-12.20

IPSRPAPKPP

8.80

-5.40

-15.57

HKQHKPKVKP

8.82

-1.51

-11.68

P53238

AGRPIPPAPT

8.70

-2.31

-12.48

GRPIPPAPTH

8.98

0.15

-10.02

PIPPAPTHYN

11.28

-0.88

-11.05

P40041

IPLSPPSSSN

12.00

-2.13

-12.30

PLSPPSSSNM

12.52

-1.40

-11.57

KIPLSPPSSS

12.87

-2.28

-12.45

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER