ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-29.PDB
Scoring matrix: HSE1_1SEM-29_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.63
Foldx random average score for Saccharomyces cerevisiae: 15.971

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5099
 Total fragments: 1032783
Proteins after disorder filtering: 2934
 Total fragments: 42816
Proteins after pattern filtering: 1485
 Total fragments: 9679
Proteins after MINT filtering: 18
 Total fragments: 401


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.63

-1.66

0.00

Best peptides

HRFPRPKKMK

0.00

-8.41

-6.75

         
Interactors      
Q06604

EKPLLPTRPN

7.70

-14.98

-13.32

LLPTRPNKAE

7.90

-11.29

-9.63

SPPPLPTRRD

8.44

-12.35

-10.69

Q06108

DPPPQPRRLS

8.02

-12.66

-11.00

INMPIPKKLP

8.47

-11.32

-9.66

PRSPYYINMP

12.20

-9.07

-7.41

P40073

GYPQQQPSHT

14.52

-6.92

-5.26

P25604

NTPPLPPKPK

6.05

-10.90

-9.24

QAPSLPPKPN

7.62

-11.05

-9.39

PLPPKPKSPH

9.26

-10.62

-8.96

P40325

SQPPRPPRPA

5.05

-14.90

-13.24

SQPRPPPRPQ

8.72

-11.57

-9.91

PRPPRPAANL

9.74

-10.23

-8.57

O13527

PLNPKGKKLR

7.96

-9.41

-7.75

LNVPLNPKGK

11.93

-7.10

-5.44

PQSQFPQYPS

12.98

-9.34

-7.68

P48524

KRKPLLRPQR

9.35

-9.10

-7.44

FPPKRKPLLR

9.46

-14.62

-12.96

KPLLRPQRSD

9.79

-10.55

-8.89

Q06412

PNSPKSPRDS

9.78

-10.07

-8.41

EFFTKPPPPL

10.34

-10.13

-8.47

RRPPPPPPLL

10.58

-10.00

-8.34

Q66RC5

LIPDNPGRLL

9.89

-11.98

-10.32

PSPLIPDNPG

11.49

-9.90

-8.24

ISNPSPLIPD

14.92

-7.16

-5.50

P36037

KPPLKLPINV

12.13

-9.47

-7.81

GKPPLKLPIN

12.53

-11.35

-9.69

PPLKLPINVS

12.85

-10.47

-8.81

P36041

VPPNFPQRMM

8.92

-14.70

-13.04

LRPVIPRGPS

9.67

-10.37

-8.71

PQPPYPNMML

10.66

-11.14

-9.48

Q04439

PPPPPSSKPK

10.18

-9.33

-7.67

SRHSKKPAPP

11.59

-7.62

-5.96

QSNARPSPPT

11.95

-9.38

-7.72

P53901

PLPPIPTRDD

7.97

-12.52

-10.86

NQPPLPPIPT

8.67

-11.24

-9.58

NSPKLPPLPT

10.16

-11.56

-9.90

Q12446

PPPPRASRPT

8.62

-13.97

-12.31

PLPQLPNRNN

8.95

-12.47

-10.81

FPFPIPEIPS

9.44

-10.31

-8.65

P40453

KPPDLPIRLR

7.79

-14.24

-12.58

IRLRKRPPPP

9.75

-9.63

-7.97

PDLPIRLRKR

10.18

-9.83

-8.17

P40343

LAPSDPPYPK

12.28

-10.19

-8.53

PSDPPYPKEE

13.73

-4.98

-3.32

QQPSPQPQPI

14.31

-7.07

-5.41

Q03497

KPKVKPSKPE

7.44

-10.20

-8.54

NGKFIPSRPA

8.94

-12.42

-10.76

VKKSFPSKNP

10.01

-8.47

-6.81

P53238

GRPIPPAPTH

12.53

-7.88

-6.22

KPAGRPIPPA

13.32

-10.23

-8.57

QKPAGRPIPP

13.68

-10.02

-8.36

 


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