ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-27.PDB
Scoring matrix: HSE1_1SEM-27_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 16.39
Foldx random average score for Saccharomyces cerevisiae: 17.847

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5099
 Total fragments: 1114675
Proteins after disorder filtering: 3271
 Total fragments: 102570
Proteins after pattern filtering: 1615
 Total fragments: 14373
Proteins after MINT filtering: 20
 Total fragments: 503


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

16.39

-1.97

0.00

Best peptides

RHRHRWRRK

0.00

-3.89

-1.92

         
Interactors      
Q07660

PSAFKPIGP

14.49

-1.35

0.62

Q06604

KGPRMPSRG

11.75

-8.36

-6.39

FEKGPRMPS

12.62

-6.29

-4.32

KPAPPVSRS

12.77

-5.80

-3.83

Q06108

RTPCKSPYS

11.83

-4.30

-2.33

PCKSPYSPY

12.58

-4.46

-2.49

IRTPCKSPY

12.98

-2.67

-0.70

P40073

FDGYPQQQP

13.11

-2.09

-0.12

YPQQQPSHT

16.06

-2.48

-0.51

DGYPQQQPS

17.79

-1.37

0.60

P25604

KSPHLKPPL

12.26

-4.95

-2.98

LKPPLPPPP

13.79

-5.20

-3.23

PKSPHLKPP

13.90

-3.95

-1.98

P40325

PWTYPPRFY

11.23

-1.50

0.47

RPPPRPQQN

11.46

-3.83

-1.86

PTSSQPRPP

12.01

-4.35

-2.38

O13527

FYGHPSMIP

10.53

-6.46

-4.49

YGHPSMIPY

10.95

-4.19

-2.22

FPQYPSSVG

11.50

-1.27

0.70

P48524

KRKPLLRPQ

11.74

-4.80

-2.83

SGFPPKRKP

12.47

-2.05

-0.08

FPPKRKPLL

14.19

-2.30

-0.33

Q06412

RRPPPPPPL

9.47

-7.81

-5.84

RPPPPPPLL

11.67

-5.19

-3.22

VKERRPPPP

12.27

-7.05

-5.08

Q66RC5

SNPSPLIPD

11.08

-4.28

-2.31

IPDNPGRLL

12.73

-4.43

-2.46

LIPDNPGRL

13.76

-4.40

-2.43

P36037

GKPPLKLPI

17.02

-4.46

-2.49

DGKPPLKLP

17.05

-4.26

-2.29

PPLKLPINV

17.71

-2.07

-0.10

P36041

FPMHPNFPN

11.40

-6.43

-4.46

QPPYPNMML

11.52

-3.10

-1.13

LPQGFPIPP

11.84

-5.92

-3.95

Q04439

KKPAPPPPG

10.81

-6.90

-4.93

QSNARPSPP

11.17

-4.68

-2.71

RHSKKPAPP

12.17

-5.65

-3.68

P53901

YNQPPLPPI

12.34

-4.03

-2.06

RPIPPLPTE

12.53

-3.73

-1.76

SPNSHPHPS

13.05

-3.70

-1.73

Q12446

RGPAPPPPP

8.50

-6.73

-4.76

RLPAPPPPP

9.12

-6.86

-4.89

KHKAPPPPP

10.06

-6.29

-4.32

P40453

RKRPPPPPP

9.42

-6.86

-4.89

RLRKRPPPP

11.10

-3.99

-2.02

RPPPPPPVS

11.93

-4.41

-2.44

P40343

LAPSDPPYP

12.96

-3.68

-1.71

VELAPSDPP

14.59

-4.64

-2.67

SPQPQPIHS

14.99

-2.38

-0.41

Q03497

FIPSRPAPK

10.71

-4.37

-2.40

SRPAPKPPS

11.16

-5.59

-3.62

NGKFIPSRP

11.79

-2.30

-0.33

P53238

KPAGRPIPP

10.84

-4.94

-2.97

IPPAPTHYN

12.78

-3.75

-1.78

RPIPPAPTH

12.96

-4.19

-2.22

P40041

IPLSPPSSS

12.69

-3.23

-1.26

PLSPPSSSN

16.73

-2.28

-0.31

 


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