ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-26.PDB
Scoring matrix: HSE1_1SEM-26_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.27
Foldx random average score for Saccharomyces cerevisiae: 12.632

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 916698
Proteins after disorder filtering: 3074
 Total fragments: 56730
Proteins after pattern filtering: 1566
 Total fragments: 12480
Proteins after MINT filtering: 19
 Total fragments: 506


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.27

-1.01

0.00

Best peptides

EDRPKRRPH

0.00

-7.89

-6.88

         
Interactors      
Q06604

PPLPTRRDH

4.71

-10.25

-9.23

EKGPRMPSR

5.22

-7.81

-6.79

SSPPPLPTR

5.56

-9.88

-8.87

Q06108

TDPPPQPRR

4.48

-10.25

-9.23

DPPPQPRRL

7.78

-7.67

-6.66

PPPQPRRLS

8.45

-7.72

-6.71

P40073

GYPQQQPSH

7.67

-6.41

-5.40

DGYPQQQPS

11.51

-7.06

-6.04

P25604

LPPKPKSPH

5.22

-6.86

-5.85

KSPHLKPPL

6.81

-6.01

-5.00

TPPLPPKPK

8.58

-4.16

-3.15

P40325

QSQPPRPPR

2.96

-11.62

-10.60

SSQPRPPPR

5.17

-6.90

-5.89

PRPPPRPQQ

5.98

-9.38

-8.37

O13527

SAVPENPHH

6.46

-4.15

-3.14

IHPRGIPGY

7.73

-5.64

-4.63

YGHPSMIPY

8.08

-5.68

-4.67

P48524

RKPLLRPQR

3.68

-8.93

-7.92

GFPPKRKPL

5.29

-9.77

-8.75

FPPKRKPLL

7.13

-6.47

-5.46

Q06412

RRPPPPPPL

6.88

-8.28

-7.26

ERRPPPPPP

7.51

-7.00

-5.99

RPPPPPPLL

7.79

-7.22

-6.21

Q66RC5

PLIPDNPGR

7.38

-5.21

-4.20

NPSPLIPDN

7.86

-6.07

-5.06

PDNPGRLLS

10.93

-6.13

-5.12

P36037

KPPLKLPIN

7.61

-6.93

-5.92

GKPPLKLPI

9.23

-6.39

-5.38

DGKPPLKLP

11.15

-6.68

-5.67

P36041

PGFFPMHPN

7.11

-6.33

-5.32

GVPPNFPQR

7.33

-6.24

-5.23

MPPPPPPGF

7.36

-7.83

-6.82

Q04439

SSKPKEPMF

7.64

-5.78

-4.77

NNIPTPPQN

7.64

-5.02

-4.00

PPPPGMQNK

8.55

-7.73

-6.72

P53901

PPLPPIPTR

6.40

-7.48

-6.47

MAMRPIPPL

7.90

-6.68

-5.67

SSSPNSHPH

8.20

-5.10

-4.09

Q12446

PPPPPRASR

4.54

-9.28

-8.26

PAPPPPPRR

5.50

-9.30

-8.29

PAPPPPPHR

5.74

-9.20

-8.18

P40453

WKPPDLPIR

7.23

-9.05

-8.04

EIPPPLPPK

7.34

-8.72

-7.71

PPDLPIRLR

7.43

-6.89

-5.88

P40343

PSPQPQPIH

7.51

-6.09

-5.08

ELAPSDPPY

7.99

-5.50

-4.49

SDPPYPKEE

10.34

-3.66

-2.65

Q03497

KFIPSRPAP

6.32

-7.38

-6.37

HKPKVKPSK

6.84

-6.16

-5.15

THAPTTPNR

7.75

-9.95

-8.93

P53238

RPIPPAPTH

5.90

-7.47

-6.46

QKPAGRPIP

9.22

-7.90

-6.89

AGRPIPPAP

9.56

-6.27

-5.25

P40041

KIPLSPPSS

10.61

-5.33

-4.32

PLSPPSSSN

10.64

-3.14

-2.13

NGRTLPPVP

10.66

-4.85

-3.84

 


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