ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-23.PDB
Scoring matrix: HSE1_1SEM-23_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.39
Foldx random average score for Saccharomyces cerevisiae: 10.489

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2198915
Proteins after random average filtering: 5100
 Total fragments: 995309
Proteins after disorder filtering: 3258
 Total fragments: 47462
Proteins after pattern filtering: 1386
 Total fragments: 5095
Proteins after MINT filtering: 19
 Total fragments: 178


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.39

-0.71

0.00

Best peptides

RPLRPRY

0.00

-5.73

-5.02

         
Interactors      
Q06604

LPTRPNK

4.83

-6.31

-5.60

KGPRMPS

5.21

-4.35

-3.64

KPLLPTR

7.30

-6.40

-5.69

Q06108

TDPRSPY

5.31

-4.43

-3.72

TPCKSPY

6.26

-4.34

-3.63

KSPYSPY

6.50

-6.81

-6.10

P40073

YPQQQPS

9.17

-3.00

-2.29

PQQQPSH

9.83

-3.69

-2.98

P25604

PHLKPPL

6.11

-5.87

-5.16

LPPKPNT

6.80

-5.51

-4.80

LPPKPKS

6.86

-6.26

-5.55

P40325

QPPRPPR

3.64

-5.42

-4.71

RPPRPAA

3.86

-8.08

-7.37

PPPRPQQ

5.99

-4.66

-3.95

O13527

HPSMIPY

5.34

-6.27

-5.56

IHPRGIP

5.73

-5.64

-4.93

MSPMYFP

5.74

-6.51

-5.80

P48524

PPKRKPL

4.95

-6.06

-5.35

PLLRPQR

5.03

-6.25

-5.54

FPPKRKP

5.99

-5.44

-4.73

Q06412

NSPKSPR

7.41

-2.48

-1.77

FSPNSPK

8.89

-3.98

-3.27

SPKSPRD

9.91

-2.75

-2.04

Q66RC5

IPDNPGR

9.27

-3.26

-2.55

SPLIPDN

9.57

-4.63

-3.92

P36037

PPLKLPI

6.19

-4.55

-3.84

KPPLKLP

7.87

-5.35

-4.64

P36041

RPVIPRG

6.35

-6.39

-5.68

QQPQPPY

6.96

-2.96

-2.25

NGPMPPL

7.14

-5.27

-4.56

Q04439

KPKEPMF

5.22

-4.38

-3.67

SKPKEPM

6.71

-1.52

-0.81

KKPAPPP

7.03

-4.47

-3.76

P53901

MRPIPPL

6.75

-5.77

-5.06

LPPIPTR

7.79

-5.10

-4.39

NSPKLPP

8.00

-3.36

-2.65

Q12446

PPPRRGP

6.05

-5.30

-4.59

RLPAPPP

6.62

-5.29

-4.58

RGPAPPP

6.77

-5.49

-4.78

P40453

KPPDLPI

8.16

-2.42

-1.71

KVPEPPS

8.88

-1.36

-0.65

PSWKPPD

8.89

-4.79

-4.08

P40343

QPQQPSP

7.96

-3.57

-2.86

QQPSPQP

9.08

-2.49

-1.78

PQPQPIH

9.59

-3.14

-2.43

Q03497

IPSRPAP

5.73

-5.10

-4.39

KPSKPEA

6.25

-4.80

-4.09

HKPKVKP

6.28

-4.90

-4.19

P53238

PAGRPIP

6.94

-5.56

-4.85

KPAGRPI

8.00

-3.24

-2.53

QKPAGRP

8.03

-3.93

-3.22

P40041

KIPLSPP

8.91

-4.89

-4.18

IPLSPPS

9.40

-4.29

-3.58

 


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