ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-21.PDB
Scoring matrix: HSE1_1SEM-21_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 24.0
Foldx random average score for Saccharomyces cerevisiae: 21.967

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1229654
Proteins after disorder filtering: 3047
 Total fragments: 51616
Proteins after pattern filtering: 1249
 Total fragments: 3682
Proteins after MINT filtering: 19
 Total fragments: 115


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

24.00

0.30

0.00

Best peptides

WWKRGRPHRR

0.00

-1.64

-1.94

         
Interactors      
Q06604

EKGPRMPSRG

13.53

-5.75

-6.05

PLLPTRPNKA

14.28

-3.72

-4.02

PTPPSPPAKR

17.05

-5.59

-5.89

Q06108

TDPRSPYYIN

17.77

-4.49

-4.79

KTDPRSPYYI

18.67

-3.32

-3.62

DPPPQPRRLS

18.76

-4.78

-5.08

P40073

GYPQQQPSHT

17.66

-3.16

-3.46

P25604

PPKPKSPHLK

14.90

-4.29

-4.59

SLPPKPNTQL

20.13

-2.37

-2.67

PPKPNTQLQQ

20.70

-3.37

-3.67

P40325

YVQPGDPRLG

17.34

-5.02

-5.32

SRPHQRPSTM

19.28

-4.10

-4.40

PRPPRPAANL

20.13

-3.87

-4.17

O13527

PLNPKGKKLR

13.26

-5.74

-6.04

IHPRGIPGYA

16.12

-4.78

-5.08

SMIPYTPYQM

17.26

-0.58

-0.88

P48524

RKPLLRPQRS

13.90

-7.28

-7.58

FPPKRKPLLR

15.54

-3.46

-3.76

Q06412

PPPPLSTSRN

15.98

-5.63

-5.93

PKSPRDSSKQ

17.71

-3.23

-3.53

PNSPKSPRDS

19.25

-2.33

-2.63

Q66RC5

PLIPDNPGRL

15.29

-6.21

-6.51

P36037

PPLKLPINVS

18.66

-1.56

-1.86

KPPLKLPINV

20.88

-1.83

-2.13

P36041

HQGPQFPVMG

17.44

-3.94

-4.24

GVPPNFPQRM

17.64

-5.59

-5.89

SPMPIPSIIN

19.49

-2.18

-2.48

Q04439

NNIPTPPQNR

17.11

-3.49

-3.79

PPPPGMQNKA

17.14

-3.69

-3.99

SSKPKEPMFE

17.59

-4.67

-4.97

P53901

PPIPTRDDMS

17.35

-1.30

-1.60

DPIILPPTFS

18.89

-5.44

-5.74

PPLPTTSNSN

19.33

-1.59

-1.89

Q12446

RPLPQLPNRN

11.96

-4.27

-4.57

ALPPASPEVR

17.81

-4.71

-5.01

PIPPTLPSTT

17.92

-2.94

-3.24

P40453

WKPPDLPIRL

14.38

-6.47

-6.77

PDLPIRLRKR

14.79

-6.04

-6.34

TKVPEPPSWK

16.92

-4.62

-4.92

P40343

SPQPQPIHSV

21.08

-1.22

-1.52

Q03497

THAPTTPNRT

13.60

-2.74

-3.04

PLPPIPPTKS

17.47

-3.81

-4.11

FPSKNPLKNS

17.88

-2.79

-3.09

P53238

PIPPAPTHYN

17.02

-3.33

-3.63

P40041

KIPLSPPSSS

19.51

-3.42

-3.72

 


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