ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-20.PDB
Scoring matrix: HSE1_1SEM-20_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 22.8
Foldx random average score for Saccharomyces cerevisiae: 22.013

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1043158
Proteins after disorder filtering: 3210
 Total fragments: 58526
Proteins after pattern filtering: 1417
 Total fragments: 5220
Proteins after MINT filtering: 19
 Total fragments: 178


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

22.80

-0.10

0.00

Best peptides

YRFRFGRRR

0.00

-5.61

-5.51

         
Interactors      
Q06604

PPPLPTRRD

13.11

-7.08

-6.98

GPRMPSRGR

13.78

-4.89

-4.79

KPLLPTRPN

15.44

-6.06

-5.96

Q06108

TDPPPQPRR

14.31

-9.56

-9.46

QPATPGSTR

14.84

-5.56

-5.46

PRSPYYINM

16.72

-8.43

-8.33

P40073

GYPQQQPSH

21.31

-2.90

-2.80

P25604

LPPKPNTQL

19.06

-7.68

-7.58

PPKPNTQLQ

19.54

-6.21

-6.11

LPPKPKSPH

20.37

-5.86

-5.76

P40325

PRPPPRPQQ

15.47

-7.42

-7.32

RPPRPAANL

16.29

-7.47

-7.37

YVQPGDPRL

17.44

-10.49

-10.39

O13527

KIHPRGIPG

18.20

-6.90

-6.80

PRGIPGYAL

18.26

-4.69

-4.59

PLNPKGKKL

19.11

-7.61

-7.51

P48524

RKPLLRPQR

13.24

-7.49

-7.39

PLLRPQRSD

13.43

-5.56

-5.46

KRKPLLRPQ

13.49

-6.74

-6.64

Q06412

PPPPLSTSR

15.19

-6.43

-6.33

PNSPKSPRD

18.82

-6.35

-6.25

PKLPPLNTR

19.11

-7.38

-7.28

Q66RC5

IPDNPGRLL

15.85

-7.08

-6.98

PLIPDNPGR

20.59

-4.70

-4.60

P36037

KPPLKLPIN

19.55

-7.95

-7.85

GKPPLKLPI

21.87

-6.47

-6.37

P36041

PPNFPQRMM

15.74

-8.48

-8.38

MPPPPGLVQ

16.21

-7.76

-7.66

NSPMPIPSI

17.69

-7.65

-7.55

Q04439

APPPPGMQN

16.83

-5.02

-4.92

IPTPPQNRD

16.89

-8.51

-8.41

PSSKPKEPM

19.86

-5.90

-5.80

P53901

LPPLPTTSN

15.19

-6.61

-6.51

IPPLPTESE

17.08

-3.79

-3.69

RPIPPLPTE

18.28

-7.50

-7.40

Q12446

PPPPPRASR

14.92

-8.74

-8.64

LPQLPNRNN

15.44

-6.86

-6.76

NRPLPQLPN

15.83

-3.92

-3.82

P40453

PPDLPIRLR

14.95

-6.75

-6.65

PDLPIRLRK

16.89

-8.40

-8.30

DCPRCGPTA

18.59

-3.67

-3.57

P40343

PSDPPYPKE

20.89

-5.03

-4.93

PQPQPIHSV

21.38

-6.01

-5.91

Q03497

TTGLPGSPQ

16.98

-4.04

-3.94

HKPKVKPSK

18.88

-6.94

-6.84

PPIPPTKSK

19.48

-7.56

-7.46

P53238

IPPAPTHYN

19.53

-5.49

-5.39

RPIPPAPTH

20.03

-8.18

-8.08

PPAPTHYNN

20.91

-4.81

-4.71

P40041

PLSPPSSSN

18.43

-4.44

-4.34

 


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