ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-2.PDB
Scoring matrix: HSE1_1SEM-2_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.03
Foldx random average score for Saccharomyces cerevisiae: 24.784

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5099
 Total fragments: 1252281
Proteins after disorder filtering: 3178
 Total fragments: 116361
Proteins after pattern filtering: 1632
 Total fragments: 19502
Proteins after MINT filtering: 20
 Total fragments: 660


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.03

10.06

0.00

Best peptides

IRRHPPRDPR

0.00

0.44

-9.62

         
Interactors      
Q07660

TPSAFKPIGP

18.55

-3.54

-13.60

Q06604

IPSSKPAGEA

11.38

-1.14

-11.20

TMKNKPKPTP

11.60

-5.69

-15.75

KPKPTPPSPP

11.90

-5.54

-15.60

Q06108

KSTDPPPQPR

11.73

-3.47

-13.53

INMPIPKKLP

12.78

-2.37

-12.43

TPCKSPYSPY

13.01

-5.78

-15.84

P40073

QFDGYPQQQP

18.67

-1.11

-11.17

P25604

PPLPPPPPPQ

10.83

-6.49

-16.55

KPPLPPPPPP

10.96

-3.96

-14.02

SPHLKPPLPP

11.73

-4.73

-14.79

P40325

PTSSQPRPPP

10.14

-4.48

-14.54

PRPPRPAANL

12.07

-2.56

-12.62

QPPRPPRPAA

12.08

-2.83

-12.89

O13527

PLPDLPPESP

12.37

-3.61

-13.67

PRGIPGYALH

12.78

-3.36

-13.42

TPLSTPSPES

12.82

-1.84

-11.90

P48524

PPKRKPLLRP

9.48

-5.99

-16.05

KPLLRPQRSD

14.37

-1.41

-11.47

DSGFPPKRKP

15.58

-0.91

-10.97

Q06412

VKERRPPPPP

9.13

-9.31

-19.37

ERRPPPPPPL

11.53

-3.00

-13.06

KERRPPPPPP

12.87

-4.95

-15.01

Q66RC5

IPDNPGRLLS

10.64

-3.42

-13.48

ISNPSPLIPD

15.75

-1.98

-12.04

PSPLIPDNPG

16.56

-2.49

-12.55

P36037

PPLKLPINVS

13.03

-4.64

-14.70

EDGKPPLKLP

22.17

2.87

-7.19

GKPPLKLPIN

22.67

0.59

-9.47

P36041

VPPNFPQRMM

9.65

-4.05

-14.11

LRPVIPRGPS

10.14

-3.51

-13.57

QRMMPPPPGL

12.65

-5.24

-15.30

Q04439

PPSSKPKEPM

8.75

-6.77

-16.83

IPPPPPPPPP

9.00

-5.58

-15.64

ARPSPPTAAT

10.35

-1.16

-11.22

P53901

HNYNQPPLPP

11.74

-1.05

-11.11

QPPLPPIPTR

13.89

-2.89

-12.95

SGLNSPKLPP

13.92

-1.68

-11.74

Q12446

VRLPAPPPPP

6.78

-5.46

-15.52

NRNNRPVPPP

7.86

-7.74

-17.80

PPRRGPAPPP

8.95

-5.51

-15.57

P40453

LRKRPPPPPP

6.75

-8.71

-18.77

TPEIPPPLPP

10.64

-3.68

-13.74

KRPPPPPPVS

10.73

-7.54

-17.60

P40343

APSDPPYPKE

12.67

-2.34

-12.40

HVELAPSDPP

13.90

-2.35

-12.41

LAPSDPPYPK

14.65

-4.22

-14.28

Q03497

IPSRPAPKPP

10.63

-5.46

-15.52

HKQHKPKVKP

11.81

-1.47

-11.53

VKKSFPSKNP

12.62

-3.01

-13.07

P53238

GRPIPPAPTH

12.48

-0.47

-10.53

KPAGRPIPPA

13.12

-1.92

-11.98

AGRPIPPAPT

16.86

-2.90

-12.96

P40041

IPLSPPSSSN

10.68

-1.66

-11.72

KIPLSPPSSS

16.20

-2.62

-12.68

PLSPPSSSNM

20.03

-1.05

-11.11

 


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