ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-16.PDB
Scoring matrix: HSE1_1SEM-16_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.46
Foldx random average score for Saccharomyces cerevisiae: 18.756

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 1114223
Proteins after disorder filtering: 3278
 Total fragments: 91399
Proteins after pattern filtering: 1556
 Total fragments: 8838
Proteins after MINT filtering: 20
 Total fragments: 262


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

19.46

3.25

0.00

Best peptides

RMPIRSRRF

0.00

3.06

-0.19

         
Interactors      
Q07660

PSAFKPIGP

17.74

-0.89

-4.13

Q06604

KGPRMPSRG

9.10

-5.57

-8.82

PPPLPTRRD

10.29

-3.86

-7.11

YSNIPSSKP

11.44

-2.90

-6.14

Q06108

KTDPRSPYY

12.24

2.52

-0.73

PPPQPRRLS

12.57

-0.74

-3.99

LMNLPGVSP

12.86

-0.69

-3.94

P40073

FDGYPQQQP

16.39

0.36

-2.89

P25604

LPPKPKSPH

12.25

-2.15

-5.39

KPKSPHLKP

12.69

-2.12

-5.37

PPPQPASNA

14.93

-1.63

-4.88

P40325

HQSRPHQRP

10.64

-5.24

-8.48

LPWTYPPRF

11.21

-4.29

-7.54

PWTYPPRFY

11.64

0.11

-3.14

O13527

FPPGPQSQF

11.14

-2.20

-5.45

FPQYPSSVG

11.95

-0.73

-3.98

KIHPRGIPG

12.99

0.54

-2.71

P48524

KPLLRPQRS

9.59

-2.06

-5.30

PKRKPLLRP

12.65

-4.18

-7.42

PLLRPQRSD

14.56

-3.13

-6.38

Q06412

PMVSPSSQS

12.60

2.51

-0.74

PNSPKSPRD

13.23

-0.08

-3.33

KPPPPLSTS

14.11

-1.02

-4.27

Q66RC5

SPLIPDNPG

15.98

-0.55

-3.79

SNPSPLIPD

16.27

1.62

-1.63

PDNPGRLLS

17.12

1.77

-1.48

P36037

KPPLKLPIN

13.99

0.34

-2.91

PPLKLPINV

18.34

0.23

-3.02

P36041

PMPIPSIIN

9.87

-2.72

-5.96

VPPNFPQRM

12.92

-0.48

-3.73

PPNFPQRMM

13.59

-2.01

-5.25

Q04439

APPPPGMQN

14.20

0.30

-2.95

IPTPPQNRD

14.84

-1.69

-4.94

PPPPPSSKP

15.23

-2.98

-6.22

P53901

PNSHPHPSG

14.03

0.08

-3.17

DPIILPPTF

14.84

-3.58

-6.83

SSSPNSHPH

15.07

1.86

-1.39

Q12446

APPPPPRRG

10.49

-2.16

-5.41

LPQLPNRNN

11.56

-1.38

-4.63

APPPPPHRH

11.87

0.17

-3.08

P40453

PDLPIRLRK

14.92

2.39

-0.85

VPEPPSWKP

15.96

-2.16

-5.41

DCPRCGPTA

15.97

-3.05

-6.29

P40343

PSPQPQPIH

16.04

2.60

-0.65

QPQQPSPQP

16.36

-1.09

-4.34

VELAPSDPP

16.65

1.09

-2.16

Q03497

FPSKNPLKN

11.57

-1.64

-4.88

KQHKPKVKP

12.91

-1.92

-5.17

APTTPNRTS

13.16

-0.27

-3.52

P53238

IPPAPTHYN

12.98

-2.26

-5.50

RPIPPAPTH

15.54

-0.24

-3.49

KPAGRPIPP

17.89

-2.41

-5.66

P40041

PLSPPSSSN

14.84

1.78

-1.47

IPLSPPSSS

15.23

-0.15

-3.40

KIPLSPPSS

17.84

0.35

-2.90

 


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