ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-15.PDB
Scoring matrix: HSE1_1SEM-15_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 21.96
Foldx random average score for Saccharomyces cerevisiae: 16.386

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 826185
Proteins after disorder filtering: 2848
 Total fragments: 32160
Proteins after pattern filtering: 1191
 Total fragments: 3779
Proteins after MINT filtering: 17
 Total fragments: 149


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

21.96

-0.36

0.00

Best peptides

YPFIIHRKR

0.00

-8.44

-8.08

         
Interactors      
Q06604

GPRMPSRGR

11.75

-7.49

-7.13

TPPSPPAKR

12.35

-6.66

-6.30

SSPPPLPTR

13.63

-6.49

-6.13

Q06108

QPATPGSTR

12.53

-6.41

-6.05

TDPPPQPRR

13.92

-5.52

-5.16

PPPQPRRLS

14.47

-6.06

-5.70

P40073

YPQQQPSHT

14.96

-4.35

-3.99

P25604

KPKSPHLKP

11.72

-6.99

-6.63

LPPKPNTQL

14.50

-6.62

-6.26

P40325

RPHQRPSTM

10.93

-6.03

-5.67

HQSRPHQRP

11.07

-9.26

-8.90

QSQPPRPPR

12.06

-6.31

-5.95

O13527

MIPYTPYQM

12.21

-5.01

-4.65

VPENPHHAS

14.02

-5.81

-5.45

HPSMIPYTP

14.69

-6.54

-6.18

P48524

RKPLLRPQR

7.74

-7.87

-7.51

PPKRKPLLR

10.67

-8.70

-8.34

FPPKRKPLL

14.56

-7.53

-7.17

Q06412

PKLPPLNTR

13.54

-5.64

-5.28

PPPPLSTSR

14.49

-6.03

-5.67

SPNSPKSPR

15.17

-4.22

-3.86

Q66RC5

PLIPDNPGR

13.26

-6.15

-5.79

P36037

KPPLKLPIN

12.80

-7.32

-6.96

PPLKLPINV

15.99

-4.96

-4.60

P36041

PPNFPQRMM

10.29

-6.85

-6.49

HPNFPNGPM

11.33

-3.71

-3.35

GFPIPPNGM

12.35

-6.35

-5.99

Q04439

NIPTPPQNR

11.24

-6.06

-5.70

KPAPPPPGM

13.97

-5.58

-5.22

PSSKPKEPM

14.60

-6.31

-5.95

P53901

PPIPTRDDM

12.34

-8.33

-7.97

PPLPPIPTR

13.30

-5.75

-5.39

PNSHPHPSG

14.09

-3.06

-2.70

Q12446

RPLPQLPNR

9.79

-8.16

-7.80

PPPPPRASR

10.58

-6.96

-6.60

LPPASPEVR

11.71

-6.63

-6.27

P40453

PPDLPIRLR

11.78

-8.38

-8.02

WKPPDLPIR

12.27

-6.88

-6.52

PPPPPPVSM

14.75

-7.19

-6.83

Q03497

FPSKNPLKN

12.94

-5.43

-5.07

HKPKVKPSK

13.25

-4.43

-4.07

LPPIPPTKS

13.86

-7.35

-6.99

P53238

PPAPTHYNN

12.39

-4.59

-4.23

 


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