ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-14.PDB
Scoring matrix: HSE1_1SEM-14_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.6
Foldx random average score for Saccharomyces cerevisiae: 16.751

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2188715
Proteins after random average filtering: 5100
 Total fragments: 919878
Proteins after disorder filtering: 2971
 Total fragments: 36826
Proteins after pattern filtering: 1221
 Total fragments: 4285
Proteins after MINT filtering: 19
 Total fragments: 158


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.60

-1.72

0.00

Best peptides

WWFRIHKKR

0.00

-5.54

-3.82

         
Interactors      
Q06604

GPRMPSRGR

10.06

-7.16

-5.44

EKGPRMPSR

10.77

-6.16

-4.44

TPPSPPAKR

11.02

-4.97

-3.25

Q06108

TDPPPQPRR

12.38

-2.90

-1.18

QPATPGSTR

13.35

-5.51

-3.79

TDPRSPYYI

14.02

-3.79

-2.07

P40073

YPQQQPSHT

14.52

-4.06

-2.34

P25604

LPPKPNTQL

14.51

-5.78

-4.06

PKPKSPHLK

15.07

-5.03

-3.31

TPPLPPKPK

15.45

-6.70

-4.98

P40325

SLPWTYPPR

10.78

-4.60

-2.88

RPHQRPSTM

13.19

-7.42

-5.70

QSQPPRPPR

13.38

-6.36

-4.64

O13527

MIPYTPYQM

12.86

-5.44

-3.72

VPLNPKGKK

13.90

-4.58

-2.86

IHPRGIPGY

14.16

-4.82

-3.10

P48524

PPKRKPLLR

6.57

-9.31

-7.59

RKPLLRPQR

7.53

-10.31

-8.59

KPLLRPQRS

13.95

-6.71

-4.99

Q06412

PPPPLSTSR

11.35

-7.18

-5.46

PKLPPLNTR

12.43

-5.87

-4.15

SPNSPKSPR

12.70

-3.42

-1.70

Q66RC5

PLIPDNPGR

11.66

-6.31

-4.59

P36037

KPPLKLPIN

12.54

-7.04

-5.32

PPLKLPINV

15.77

-4.98

-3.26

P36041

TDLRPVIPR

8.90

-6.57

-4.85

GVPPNFPQR

10.71

-6.22

-4.50

HPNFPNGPM

12.53

-6.29

-4.57

Q04439

NIPTPPQNR

12.37

-4.30

-2.58

PSSKPKEPM

14.34

-5.82

-4.10

PSPPTAATR

14.84

-4.18

-2.46

P53901

NDPIILPPT

12.40

-3.93

-2.21

PPLPPIPTR

12.85

-5.34

-3.62

PPIPTRDDM

15.44

-8.39

-6.67

Q12446

RPLPQLPNR

10.70

-4.81

-3.09

PPPPPRASR

11.10

-9.80

-8.08

LPPASPEVR

12.83

-5.23

-3.51

P40453

PPDLPIRLR

8.35

-8.28

-6.56

WKPPDLPIR

10.78

-6.72

-5.00

PDLPIRLRK

14.14

-4.95

-3.23

P40343

PQPQPIHSV

15.55

-2.73

-1.01

Q03497

HKPKVKPSK

13.94

-4.12

-2.40

SFPSKNPLK

14.19

-2.87

-1.15

PIPPTKSKT

14.73

-4.70

-2.98

P53238

PAGRPIPPA

15.17

-6.78

-5.06

PPAPTHYNN

15.96

-4.80

-3.08

P40041

KIPLSPPSS

15.74

-4.82

-3.10

 


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