ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-12.PDB
Scoring matrix: HSE1_1SEM-12_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.87
Foldx random average score for Saccharomyces cerevisiae: 9.980

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5099
 Total fragments: 969071
Proteins after disorder filtering: 3194
 Total fragments: 58862
Proteins after pattern filtering: 1523
 Total fragments: 8556
Proteins after MINT filtering: 20
 Total fragments: 338


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.87

-2.17

0.00

Best peptides

YRVKRRWR

0.00

-4.08

-1.91

         
Interactors      
Q07660

SAFKPIGP

7.91

-4.65

-2.48

Q06604

FEKGPRMP

4.54

-8.36

-6.19

PRMPSRGR

5.89

-7.41

-5.24

NIPSSKPA

6.93

-5.62

-3.45

Q06108

PPPQPRRL

5.20

-8.85

-6.68

TDPRSPYY

7.88

-4.89

-2.72

PPQPRRLS

8.10

-6.42

-4.25

P40073

GYPQQQPS

8.09

-5.29

-3.12

P25604

KPKSPHLK

6.00

-5.75

-3.58

HLKPPLPP

7.43

-6.12

-3.95

QAPSLPPK

7.67

-4.10

-1.93

P40325

SRPHQRPS

4.65

-7.76

-5.59

PRPPPRPQ

4.89

-7.23

-5.06

TSSQPRPP

5.11

-4.99

-2.82

O13527

GHPSMIPY

7.29

-5.14

-2.97

IHPRGIPG

7.44

-6.17

-4.00

LNVPLNPK

8.01

-4.69

-2.52

P48524

PKRKPLLR

5.38

-6.43

-4.26

RKPLLRPQ

5.43

-7.29

-5.12

GFPPKRKP

6.17

-7.17

-5.00

Q06412

SPKSPRDS

6.07

-6.93

-4.76

NSPKSPRD

6.61

-5.11

-2.94

FFTKPPPP

6.75

-3.60

-1.43

Q66RC5

SNPSPLIP

6.75

-5.71

-3.54

PDNPGRLL

8.54

-6.46

-4.29

P36037

PLKLPINV

7.85

-5.49

-3.32

KPPLKLPI

8.37

-5.63

-3.46

GKPPLKLP

8.80

-5.04

-2.87

P36041

QRMMPPPP

6.18

-6.80

-4.63

PNFPQRMM

6.54

-8.28

-6.11

RPVIPRGP

6.94

-6.82

-4.65

Q04439

GSPSELPL

6.82

-5.52

-3.35

HSKKPAPP

7.41

-5.47

-3.30

ARPSPPTA

7.52

-4.04

-1.87

P53901

MAMRPIPP

6.10

-5.79

-3.62

SSPNSHPH

7.16

-5.61

-3.44

NSPKLPPL

7.19

-4.29

-2.12

Q12446

PPPPPRRG

6.38

-7.51

-5.34

NRPLPQLP

7.07

-6.12

-3.95

PFPFPIPE

7.42

-5.67

-3.50

P40453

LRKRPPPP

5.88

-5.32

-3.15

PDLPIRLR

7.25

-7.52

-5.35

EIPPPLPP

7.76

-5.80

-3.63

P40343

QQPSPQPQ

7.11

-4.72

-2.55

PSPQPQPI

7.52

-5.04

-2.87

LAPSDPPY

7.96

-3.62

-1.45

Q03497

SRPAPKPP

6.29

-4.82

-2.65

SFPSKNPL

6.79

-6.44

-4.27

HKPKVKPS

6.98

-5.95

-3.78

P53238

QKPAGRPI

5.15

-7.86

-5.69

GRPIPPAP

8.43

-4.82

-2.65

PAGRPIPP

8.66

-3.07

-0.90

P40041

GRTLPPVP

8.45

-4.10

-1.93

KIPLSPPS

8.56

-4.19

-2.02

 


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