ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-11.PDB
Scoring matrix: HSE1_1SEM-11_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 17.11
Foldx random average score for Saccharomyces cerevisiae: 14.579

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2198915
Proteins after random average filtering: 5100
 Total fragments: 888545
Proteins after disorder filtering: 3314
 Total fragments: 68566
Proteins after pattern filtering: 1630
 Total fragments: 10446
Proteins after MINT filtering: 19
 Total fragments: 412


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

17.11

1.69

0.00

Best peptides

YEPRPPR

0.00

-6.23

-7.92

         
Interactors      
Q06604

KPLLPTR

5.41

-5.71

-7.40

PPPLPTR

6.08

-7.46

-9.15

GPRMPSR

7.05

-5.59

-7.28

Q06108

PPPQPRR

6.50

-9.31

-11.00

DPPPQPR

9.79

-4.40

-6.09

TDPRSPY

10.04

-2.99

-4.68

P40073

YPQQQPS

11.35

-4.95

-6.64

PQQQPSH

12.56

-4.66

-6.35

P25604

KPPLPPP

7.98

-7.14

-8.83

TPPLPPK

8.31

-6.22

-7.91

APSLPPK

8.61

-5.71

-7.40

P40325

QPPRPPR

3.87

-8.61

-10.30

QPRPPPR

7.26

-6.14

-7.83

RPPRPAA

7.44

-7.61

-9.30

O13527

FPQYPSS

10.15

-4.45

-6.14

IHPRGIP

10.58

-3.81

-5.50

FPPGPQS

10.76

-4.87

-6.56

P48524

PLLRPQR

5.96

-7.45

-9.14

FPPKRKP

9.52

-6.26

-7.95

PPKRKPL

9.78

-6.92

-8.61

Q06412

NSPKSPR

8.82

-1.92

-3.61

RPPPPPP

9.22

-7.25

-8.94

RRPPPPP

9.48

-6.48

-8.17

Q66RC5

IPDNPGR

7.21

-4.33

-6.02

SPLIPDN

10.48

-4.01

-5.70

PDNPGRL

12.78

-3.26

-4.95

P36037

PLKLPIN

10.87

-4.81

-6.50

KPPLKLP

11.38

-5.58

-7.27

PPLKLPI

14.44

-4.35

-6.04

P36041

PPNFPQR

8.01

-5.26

-6.95

FFPMHPN

8.16

-5.29

-6.98

YMPPPPP

8.36

-6.98

-8.67

Q04439

KPAPPPP

9.76

-5.34

-7.03

IPPPPPP

9.78

-5.52

-7.21

KKPAPPP

10.19

-5.28

-6.97

P53901

LPPIPTR

5.88

-6.09

-7.78

MRPIPPL

7.78

-5.04

-6.73

SPKLPPL

9.41

-4.42

-6.11

Q12446

LPQLPNR

6.54

-5.78

-7.47

APPPPPR

6.88

-6.81

-8.50

PPPPPRR

6.91

-7.21

-8.90

P40453

PPDLPIR

6.42

-6.68

-8.37

PPPLPPK

8.01

-7.40

-9.09

RPPPPPP

9.22

-7.25

-8.94

P40343

QPQQPSP

11.35

-4.76

-6.45

PSPQPQP

11.57

-3.86

-5.55

PSDPPYP

11.82

-3.44

-5.13

Q03497

IPSRPAP

7.61

-6.03

-7.72

APTTPNR

8.22

-4.52

-6.21

PKVKPSK

9.43

-4.39

-6.08

P53238

PAGRPIP

9.79

-5.13

-6.82

RPIPPAP

10.21

-6.11

-7.80

GRPIPPA

10.87

-4.95

-6.64

P40041

KIPLSPP

10.95

-4.08

-5.77

RTLPPVP

11.17

-4.06

-5.75

IPLSPPS

11.84

-2.91

-4.60

 


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