ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-1.PDB
Scoring matrix: HSE1_1SEM-1_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.25
Foldx random average score for Saccharomyces cerevisiae: 18.590

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2183615
Proteins after random average filtering: 5100
 Total fragments: 1211523
Proteins after disorder filtering: 3191
 Total fragments: 80233
Proteins after pattern filtering: 1599
 Total fragments: 14290
Proteins after MINT filtering: 20
 Total fragments: 517


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.25

-3.81

0.00

Best peptides

LHRIKHRRPY

0.00

-6.15

-2.34

         
Interactors      
Q07660

TPSAFKPIGP

17.13

-6.90

-3.09

Q06604

MKNKPKPTPP

9.60

-11.38

-7.57

TMKNKPKPTP

10.50

-7.81

-4.00

LLPTRPNKAE

12.64

-7.56

-3.75

Q06108

KSTDPPPQPR

11.14

-7.53

-3.72

LKSTDPPPQP

11.53

-8.20

-4.39

LMNLPGVSPS

12.15

-5.57

-1.76

P40073

FDGYPQQQPS

17.70

-4.13

-0.32

P25604

PHLKPPLPPP

10.22

-10.08

-6.27

LKPPLPPPPP

10.53

-10.67

-6.86

HLKPPLPPPP

11.53

-8.29

-4.48

P40325

TSSQPRPPPR

10.68

-8.24

-4.43

HQSRPHQRPS

11.55

-10.41

-6.60

QSRPHQRPST

11.73

-6.95

-3.14

O13527

NSKIHPRGIP

9.55

-11.21

-7.40

MSPMYFPPGP

11.21

-9.70

-5.89

ESPTEFPDPF

11.58

-7.72

-3.91

P48524

KRKPLLRPQR

7.77

-8.48

-4.67

PLLRPQRSDF

11.97

-8.92

-5.11

PKRKPLLRPQ

12.33

-10.12

-6.31

Q06412

FSPNSPKSPR

9.53

-7.72

-3.91

ERRPPPPPPL

10.78

-7.41

-3.60

VKERRPPPPP

11.61

-10.10

-6.29

Q66RC5

ISNPSPLIPD

14.44

-9.61

-5.80

PSPLIPDNPG

14.98

-6.26

-2.45

PLIPDNPGRL

16.55

-5.69

-1.88

P36037

GKPPLKLPIN

16.86

-6.13

-2.32

KPPLKLPINV

17.08

-6.20

-2.39

DGKPPLKLPI

17.53

-5.64

-1.83

P36041

LRPVIPRGPS

8.02

-10.29

-6.48

MHPNFPNGPM

8.92

-7.73

-3.92

QQQYMPPPPP

11.29

-7.95

-4.14

Q04439

RHSKKPAPPP

9.09

-6.64

-2.83

SRHSKKPAPP

10.38

-8.53

-4.72

QANIPPPPPP

10.69

-9.60

-5.79

P53901

MRPIPPLPTE

10.47

-8.94

-5.13

HNYNQPPLPP

11.68

-8.40

-4.59

AMRPIPPLPT

12.15

-8.36

-4.55

Q12446

KHKAPPPPPP

8.83

-8.48

-4.67

NRNNRPVPPP

9.56

-9.86

-6.05

NRPVPPPPPM

9.64

-8.65

-4.84

P40453

LRKRPPPPPP

7.21

-14.99

-11.18

IRLRKRPPPP

7.77

-15.70

-11.89

RLRKRPPPPP

9.75

-11.60

-7.79

P40343

LAPSDPPYPK

11.21

-9.11

-5.30

QQPSPQPQPI

13.69

-6.16

-2.35

PSDPPYPKEE

14.07

-6.03

-2.22

Q03497

QHKPKVKPSK

10.75

-5.30

-1.49

HKPKVKPSKP

12.05

-6.82

-3.01

SRPAPKPPSS

12.39

-7.29

-3.48

P53238

GRPIPPAPTH

12.22

-6.99

-3.18

QKPAGRPIPP

13.47

-7.19

-3.38

AGRPIPPAPT

16.63

-5.65

-1.84

P40041

PNGRTLPPVP

13.57

-8.89

-5.08

KIPLSPPSSS

16.81

-6.97

-3.16

PLSPPSSSNM

17.64

-5.16

-1.35

 


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