ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-9.PDB
Scoring matrix: HSE1_1OEB-9_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.02
Foldx random average score for Saccharomyces cerevisiae: 11.857

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 980756
Proteins after disorder filtering: 3140
 Total fragments: 48699
Proteins after pattern filtering: 1564
 Total fragments: 9115
Proteins after MINT filtering: 20
 Total fragments: 370


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.02

-2.37

0.00

Best peptides

YPWRNFRF

0.00

-10.54

-8.17

         
Interactors      
Q07660

SAFKPIGP

11.78

-6.07

-3.70

Q06604

KPLLPTRP

5.30

-9.88

-7.51

LPTRPNKA

5.52

-9.36

-6.99

PPPLPTRR

7.68

-10.68

-8.31

Q06108

TDPRSPYY

6.83

-7.46

-5.09

PPPQPRRL

7.00

-10.19

-7.82

KSPYSPYT

9.26

-3.97

-1.60

P40073

YPQQQPSH

10.30

-7.72

-5.35

P25604

KPPLPPPP

6.37

-10.45

-8.08

KPKSPHLK

6.56

-9.29

-6.92

LPPKPKSP

7.68

-6.35

-3.98

P40325

QPPRPPRP

3.85

-12.80

-10.43

RPPRPAAN

6.19

-8.67

-6.30

PPPRPQQN

7.88

-10.18

-7.81

O13527

IPYTPYQM

7.88

-7.84

-5.47

PRGIPGYA

8.20

-8.58

-6.21

KIHPRGIP

8.86

-7.48

-5.11

P48524

PPKRKPLL

6.43

-10.31

-7.94

KRKPLLRP

6.62

-6.75

-4.38

KPLLRPQR

6.69

-7.96

-5.59

Q06412

KERRPPPP

6.66

-7.88

-5.51

RPPPPPPL

8.27

-9.18

-6.81

KPPPPLST

8.48

-7.56

-5.19

Q66RC5

IPDNPGRL

7.47

-8.96

-6.59

SPLIPDNP

9.42

-7.95

-5.58

LIPDNPGR

9.93

-4.78

-2.41

P36037

KPPLKLPI

7.50

-8.33

-5.96

PPLKLPIN

9.69

-9.09

-6.72

PLKLPINV

11.10

-6.57

-4.20

P36041

RPVIPRGP

6.82

-9.76

-7.39

FFPMHPNF

7.06

-8.45

-6.08

FPMHPNFP

7.15

-6.15

-3.78

Q04439

KPKEPMFE

6.36

-8.80

-6.43

KKPAPPPP

8.60

-7.67

-5.30

KPAPPPPG

8.60

-8.04

-5.67

P53901

LPPIPTRD

5.82

-8.11

-5.74

MRPIPPLP

5.96

-10.55

-8.18

QPPLPPIP

7.71

-8.45

-6.08

Q12446

LPPLPNQF

6.67

-7.50

-5.13

RNNRPVPP

7.03

-7.68

-5.31

KHSLPPLP

7.32

-8.58

-6.21

P40453

LRKRPPPP

5.41

-8.97

-6.60

KPPDLPIR

7.04

-5.36

-2.99

PPDLPIRL

7.54

-9.69

-7.32

P40343

APSDPPYP

8.35

-8.41

-6.04

QPQQPSPQ

11.50

-4.44

-2.07

PQPQPIHS

11.53

-6.52

-4.15

Q03497

FPSKNPLK

5.67

-7.65

-5.28

IPSRPAPK

6.30

-8.14

-5.77

LPPIPPTK

6.48

-9.74

-7.37

P53238

KPAGRPIP

8.10

-6.47

-4.10

GRPIPPAP

9.07

-8.01

-5.64

RPIPPAPT

9.16

-7.09

-4.72

P40041

KIPLSPPS

9.13

-7.29

-4.92

GRTLPPVP

9.60

-8.24

-5.87

IPLSPPSS

10.10

-6.52

-4.15

 


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