ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-8.PDB
Scoring matrix: HSE1_1OEB-8_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.47
Foldx random average score for Saccharomyces cerevisiae: 10.553

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 1064632
Proteins after disorder filtering: 3256
 Total fragments: 69822
Proteins after pattern filtering: 1607
 Total fragments: 12634
Proteins after MINT filtering: 19
 Total fragments: 496


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.47

-0.31

0.00

Best peptides

DWPPRQHR

0.00

0.51

0.82

         
Interactors      
Q06604

SPPPLPTR

2.23

-8.03

-7.72

EKPLLPTR

3.40

-6.11

-5.80

KGPRMPSR

3.79

-7.35

-7.04

Q06108

DPPPQPRR

2.84

-7.43

-7.12

TDPPPQPR

5.30

-4.23

-3.92

KTDPRSPY

6.38

-2.51

-2.20

P40073

YPQQQPSH

8.27

-5.03

-4.72

GYPQQQPS

9.26

-2.90

-2.59

DGYPQQQP

10.22

-4.35

-4.04

P25604

QAPSLPPK

4.98

-6.96

-6.65

NTPPLPPK

5.13

-4.64

-4.33

LKPPLPPP

5.33

-7.35

-7.04

P40325

SQPPRPPR

1.30

-8.74

-8.43

RPPPRPQQ

4.05

-7.31

-7.00

SQPRPPPR

4.25

-4.72

-4.41

O13527

PLPDLPPE

6.41

-4.52

-4.21

FPPGPQSQ

6.89

-3.99

-3.68

LNVPLNPK

6.92

-6.52

-6.21

P48524

KPLLRPQR

3.12

-8.02

-7.71

FPPKRKPL

3.86

-6.00

-5.69

RKPLLRPQ

5.93

-6.13

-5.82

Q06412

RPPPPPPL

5.19

-6.53

-6.22

PPPPPPLL

5.68

-6.20

-5.89

RRPPPPPP

6.36

-5.60

-5.29

Q66RC5

LIPDNPGR

6.16

-3.64

-3.33

PSPLIPDN

7.57

-3.68

-3.37

PLIPDNPG

8.71

-3.07

-2.76

P36037

KPPLKLPI

6.69

-5.92

-5.61

GKPPLKLP

6.72

-6.36

-6.05

PPLKLPIN

7.09

-6.38

-6.07

P36041

VPPNFPQR

4.43

-6.03

-5.72

PPPPPPGF

4.89

-6.87

-6.56

MPPLPQGF

5.16

-5.11

-4.80

Q04439

IPTPPQNR

5.05

-6.09

-5.78

SKPKEPMF

5.57

-4.43

-4.12

IPPPPPPP

6.41

-6.44

-6.13

P53901

PLPPIPTR

3.35

-5.41

-5.10

NQPPLPPI

4.75

-5.82

-5.51

NSPKLPPL

4.81

-4.05

-3.74

Q12446

PPPPRASR

2.25

-7.64

-7.33

APPPPPHR

3.27

-8.40

-8.09

PLPQLPNR

3.37

-5.89

-5.58

P40453

KPPDLPIR

2.52

-7.75

-7.44

IPPPLPPK

3.32

-8.36

-8.05

PDLPIRLR

6.27

-6.43

-6.12

P40343

LAPSDPPY

5.84

-4.42

-4.11

QQPSPQPQ

6.97

-2.56

-2.25

PSPQPQPI

7.22

-2.43

-2.12

Q03497

HAPTTPNR

4.42

-5.92

-5.61

EEQPLPPI

5.64

-7.46

-7.15

KPKVKPSK

6.21

-7.56

-7.25

P53238

KPAGRPIP

7.03

-6.97

-6.66

IPPAPTHY

7.12

-4.14

-3.83

GRPIPPAP

7.13

-3.23

-2.92

P40041

GRTLPPVP

8.82

-5.47

-5.16

IPLSPPSS

9.27

-4.69

-4.38

 


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