ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-7.PDB
Scoring matrix: HSE1_1OEB-7_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 17.29
Foldx random average score for Saccharomyces cerevisiae: 14.730

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2079
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5100
 Total fragments: 2193815
Proteins after random average filtering: 5100
 Total fragments: 842508
Proteins after disorder filtering: 3153
 Total fragments: 48009
Proteins after pattern filtering: 1484
 Total fragments: 8177
Proteins after MINT filtering: 19
 Total fragments: 366


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

17.29

-3.34

0.00

Best peptides

YHPRNTRW

0.00

-7.43

-4.09

         
Interactors      
Q06604

PPPLPTRR

8.36

-9.09

-5.75

KGPRMPSR

8.89

-8.19

-4.85

KPLLPTRP

9.50

-8.82

-5.48

Q06108

TDPRSPYY

10.00

-6.81

-3.47

DPPPQPRR

10.58

-6.55

-3.21

PPPQPRRL

10.97

-7.42

-4.08

P40073

YPQQQPSH

12.56

-5.12

-1.78

PQQQPSHT

14.21

-5.52

-2.18

P25604

PLPPKPKS

10.43

-5.30

-1.96

PHLKPPLP

11.30

-7.71

-4.37

TPPLPPKP

11.48

-6.32

-2.98

P40325

QPPRPPRP

6.66

-10.05

-6.71

PHQRPSTM

8.77

-7.42

-4.08

QPRPPPRP

10.05

-7.95

-4.61

O13527

PLNPKGKK

10.77

-5.23

-1.89

NVPLNPKG

10.88

-6.38

-3.04

QMSPMYFP

11.42

-4.95

-1.61

P48524

PPKRKPLL

8.10

-8.40

-5.06

PLLRPQRS

8.22

-9.35

-6.01

KPLLRPQR

10.79

-8.17

-4.83

Q06412

KERRPPPP

10.38

-8.33

-4.99

PPPPPPLL

11.58

-6.77

-3.43

PPPPPLLY

11.71

-6.60

-3.26

Q66RC5

IPDNPGRL

13.50

-3.53

-0.19

PDNPGRLL

14.72

-4.15

-0.81

P36037

KPPLKLPI

11.64

-6.05

-2.71

PPLKLPIN

12.49

-5.95

-2.61

PLKLPINV

13.74

-5.80

-2.46

P36041

YMPPPPPP

10.01

-6.90

-3.56

PMPIPSII

10.09

-6.80

-3.46

MPPPPGLV

10.57

-7.56

-4.22

Q04439

SNARPSPP

11.85

-6.49

-3.15

APPPPGMQ

12.30

-6.86

-3.52

PPSSKPKE

12.44

-4.39

-1.05

P53901

MRPIPPLP

10.28

-8.25

-4.91

LPPIPTRD

10.50

-8.17

-4.83

MAMRPIPP

10.72

-7.96

-4.62

Q12446

APPPPPRR

9.18

-8.64

-5.30

PPPRRGPA

10.05

-8.13

-4.79

PPPPPHRH

10.07

-8.47

-5.13

P40453

PPPLPPKI

10.75

-8.21

-4.87

PPDLPIRL

11.00

-9.78

-6.44

KPPDLPIR

11.96

-5.79

-2.45

P40343

SDPPYPKE

12.66

-3.89

-0.55

QPQQPSPQ

13.04

-5.07

-1.73

SPQPQPIH

13.79

-4.89

-1.55

Q03497

FPSKNPLK

9.59

-7.71

-4.37

QHKPKVKP

9.71

-5.80

-2.46

PPIPPTKS

11.30

-6.17

-2.83

P53238

PAGRPIPP

12.60

-7.21

-3.87

KPAGRPIP

13.60

-5.92

-2.58

RPIPPAPT

13.67

-4.93

-1.59

P40041

PLSPPSSS

13.84

-4.48

-1.14

KIPLSPPS

13.88

-5.52

-2.18

 


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